Results 31 to 40 of about 4,456 (216)
The pandemic (H1N1) 2009 influenza virus is resistant to mannose-binding lectin
Virology Journal, 2011 Background Mannose-binding lectin (MBL) is an important component of innate immunity because it promotes bacterial clearance and neutralization of human influenza A viruses.
Ushirogawa Hiroshi +2 more
doaj +1 more source
Mannan‐Binding Lectin (MBL) and MBL‐Associated Serine Protease 2 (MASP‐2) Genotypes in Colorectal Cancer [PDF]
Scandinavian Journal of Immunology, 2011 AbstractMannan‐binding lectin (MBL) and MBL‐associated serine protease 2 (MASP‐2) are key factors of the lectin pathway of complement activation. Polymorphisms of the MBL2 and MASP‐2 genes affect serum levels of MBL and MASP‐2. In patients with colorectal cancer (CRC), the MBL and MASP‐2 serum levels are increased and high MASP‐2 levels are associated ...
Ytting, H +7 more
openaire +4 more sources
Mannan-binding lectin (MBL) in women with tumours of the reproductive system. [PDF]
Cancer Immunol Immunother, 2007 Mannan-binding lectin (MBL) is an important factor of innate immunity contributing to the clearance of microorganisms. Recently, an antitumourigenic role of MBL has been suggested. We investigated mbl2 genotypes, MBL concentrations, and MBL-MASP-2 complex activity in patients with ovarian cancer.
Swierzko AS +7 more
europepmc +4 more sources
Lack of the pattern recognition molecule mannose-binding lectin increases susceptibility to influenza A virus infection [PDF]
, 2010 BACKGROUND: Mannose-binding lectin (MBL), a pattern recognition innate immune molecule, inhibits influenza A virus infection in vitro. MBL deficiency due to gene polymorphism in humans has been associated with infection susceptibility.
Kazue Takahashi +6 more
core +5 more sources
Mannan-binding lectin gene polymorphisms in ulcerative colitis and Crohn's disease [PDF]
Gastroenterology, 2001 The inflammatory bowel diseases (IBD), Crohn's disease (CD), and ulcerative colitis (UC), are complex multifactorial traits involving both environmental and genetic factors. Mannan-binding lectin (MBL) plays an important role in non-specific immunity and complement activation.
A, Rector +8 more
openaire +2 more sources
Journal of Innate Immunity, 2022 Idiopathic pulmonary fibrosis (IPF) is a type of idiopathic interstitial pneumonia with a poor clinical prognosis. Increasing evidence has demonstrated that epithelial-mesenchymal transition (EMT) contributes to the production of pathogenic ...
Yunzhi Liu +10 more
doaj +1 more source
Mannan-binding lectin in cerebrospinal fluid: a leptomeningeal protein [PDF]
, 2012 BACKGROUND: Mannan-binding lectin (MBL), a protein of the innate immune response is attracting increasing clinical interest, in particularly in relation to its deficiency.
Alberto Dorta-Contreras +3 more
core +1 more source
Mediators of Inflammation, 2017 Increasing evidence links mannan-binding lectin (MBL) to late vascular complications of diabetes. MBL is a complement-activating pattern recognition molecule of the innate immune system that can mediate an inflammation response through activation of the ...
Esben Axelgaard +4 more
doaj +1 more source
Mannose binding lectin is required for alphavirus-induced arthritis/myositis [PDF]
, 2015 Mosquito-borne alphaviruses such as chikungunya virus and Ross River virus (RRV) are emerging pathogens capable of causing large-scale epidemics of virus-induced arthritis and myositis.
Blevins, Lance K. +10 more
core +1 more source
Changes in the mannan binding lectin (MBL) concentration in human milk during lactation [PDF]
Journal of Clinical Laboratory Analysis, 2002 AbstractThe mannan binding lectin (MBL) activates the complement system by the lectin pathway after the recognition of some structural motifs (saccharides) present on the surface of microorganisms. MBL has been mostly identified and quantified in human serum by ELISA or microparticle immunonephelometry assays.
Virginie, Trégoat +3 more
openaire +2 more sources