Results 51 to 60 of about 4,456 (216)

High MBL-expressing genotypes are associated with deterioration in renal function in type 2 diabetes

Frontiers in Immunology, 2022
IntroductionAccumulating evidence support that mannan-binding lectin (MBL) is a promising prognostic biomarker for risk-stratification of diabetic micro- and macrovascular complications.
G. H. Dørflinger, G. H. Dørflinger, P. H. Høyem, E. Laugesen, J. A. Østergaard, J. A. Østergaard, K. L. Funck, K. L. Funck, R. Steffensen, P. L. Poulsen, P. L. Poulsen, T. K. Hansen, M. Bjerre   +12 more
doaj   +1 more source

Role of mannose-binding lectin in the innate defense against Candida albicans: Enhancement of complement activation, but lack of opsonic function, in phagocytosis by human dendritic cells [PDF]

, 2004
Mannose-binding lectin (MBL) is a serum collectin believed to be of importance in innate immunity. We have investigated the role of MBL in the first-line defense against Candida albicans, an opportunistic fungal pathogen. MBL bound C.
Ip, WK, Lau, YL
core   +1 more source

Mannan-Binding Lectin Regulates Inflammatory Cytokine Production, Proliferation, and Cytotoxicity of Human Peripheral Natural Killer Cells

Mediators of Inflammation, 2019
Natural killer (NK) cells represent the founding members of innate lymphoid cells (ILC) and play critical roles in inflammation and the immune response. NK cell effector functions are regulated and fine-tuned by various immune modulators.
Jia Zhou, Mengyao Hu, Jie Li, Yan Liu, Jialiang Luo, Liyun Zhang, Xiao Lu, Daming Zuo, Zhengliang Chen   +8 more
doaj   +1 more source

Mannan-binding Lectin (MBL) Polymorphism and Gastric Cancer Risk in Japanese Population

Digestive Diseases and Sciences, 2008
Mannan-binding lectin (MBL) is believed to be an important constituent of the innate immune system. It has been reported that the codon 54 G/A polymorphism of exon-1 affects the MBL2 gene and alters its activity.We investigated the association between polymorphism of the MBL2 gene and gastric cancer risk as well as Helicobacter pylori infection in a ...
Fang-Yu, Wang, Tomomitsu, Tahara, Tomiyasu, Arisawa, Tomoyuki, Shibata, Hiromi, Yamashita, Masakatsu, Nakamura, Daisuke, Yoshioka, Masaaki, Okubo, Naoko, Maruyama, Toshiaki, Kamano, Yoshio, Kamiya, Masahiko, Nakamura, Hiroshi, Fujita, Mitsuo, Nagasaka, Masami, Iwata, Kazuya, Takahama, Makoto, Watanabe, Hiroshi, Nakano, Ichiro, Hirata   +18 more
openaire   +3 more sources

Mannan-Binding Lectin Levels and Activity Are Not Altered in Atopic Dermatitis Patients with a History of Eczema Herpeticum

Dermatology Research and Practice, 2011
Background. Eczema herpeticum (EH) is a potentially serious, systemic complication in subjects with atopic dermatitis (AD) caused by herpes simplex virus (HSV).
Kemp W. Bundy, Laura Y. McGirt, Lora G. Bankova, Andreas Wollenberg, Lisa A. Beck, Anna De Benedetto   +5 more
doaj   +1 more source

EIF4A3‐Induced Circular RNA circSnd1 Promotes Muscle Atrophy and Muscle Ageing by Stabilizing EEF1A1

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Muscle atrophy is a common complication of ageing, and many chronic conditions, lacks defined therapeutic interventions. It is still mostly unknown how circular RNAs contribute to muscle atrophy. Methods circRNA sequencing and quantitative real‐time PCR were performed to detect the changed circRNAs in muscle atrophy models and aged ...
Jin Li, Bing Jin, Yuwei Yan, Yuying Chen, Xiaohang Yin, Xinyi Ren, Qian Li, Jingying Chen, Siqi Wang, Tingting Yang, Yanan Zhang, Qiumeng Nie, Dongchao Lu, Ming Wu, Yan Yu, Lei Chen, Tarun Keswani, Guoping Li, Dragos Cretoiu, T. Scott Bowen, Junjie Xiao, Yongjun Zheng   +21 more
wiley   +1 more source

Simultaneous activation of complement and coagulation by MBL-associated serine protease 2.

PLoS ONE, 2007
The complement system is an important immune mechanism mediating both recognition and elimination of foreign bodies. The lectin pathway is one pathway of three by which the complement system is activated.
Anders Krarup, Russell Wallis, Julia S Presanis, Péter Gál, Robert B Sim   +4 more
doaj   +1 more source

Frequency and distribution of FCN2 and FCN3 functional variants among MBL2 genotypes. [PDF]

, 2016
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files.
Arnardottir, Margret, Bjarnadottir, Helga, Ludviksson, Bjorn Runar   +2 more
core   +1 more source

16th IHIW: Immunogenetics of Aging [PDF]

, 2013
Ageing is a process characterised by progressive loss of function in multiple different organ systems, such as the nervous, endocrine and immune systems.
Bogunia Kubik, K, CARUSO, Calogero, Constantinescu, I, Franceschi, C, Ivanova, M, Lange, A, Middleton, D., Mishra, M, Naumova, E, Oguz, F, Ozdilli, K, Pawelec, G   +11 more
core   +1 more source

Modular Nanosensing Platforms for Tuberculosis and Beyond: Engineering Biomaterials Toward Cross‐Pathogen Diagnostic Universality

MedComm – Biomaterials and Applications, Volume 4, Issue 4, December 2025.
Modular nanosensing platforms utilize nanomaterials and functionalized interfaces to amplify trace different pathogens (like tuberculosis) antigen capture, suppress matrix interference, and enable multiplex detection. Their portability and cost‐effectiveness support rapid screening in resource‐limited settings and real‐time monitoring, advancing high ...
Mei Li, Yuxin Luo, Wenqiang Li, Yiqing Wang, Yunze Tai, Zhiping Deng, Yao Luo   +6 more
wiley   +1 more source