Results 61 to 70 of about 4,456 (216)
Journal of Inflammation Research, 2022 Fanping Wang,1,2 Yonghui Yang,1,3 Zhixin Li,1,2 Yan Wang,1,4 Zhenchao Zhang,2,5 Wei Zhang,2,5 Yonghui Mu,2,5 Jingwen Yang,1,2 Lili Yu,2,5 Mingyong Wang1,2 1Henan Key Laboratory of Immunology and Targeted Drugs, School of Laboratory Medicine, Xinxiang ...
Wang F +9 more
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Cellular and Molecular Gastroenterology and Hepatology, 2022 Background & Aims: Liver fibrosis represents a hallmark of most chronic liver diseases (CLD) triggered by recurrent liver injury and subsequent myofibroblast transdifferentiations of resident hepatic stellate cells (HSCs). Mannan-binding lectin (MBL)
Jialiang Luo +10 more
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OncoImmunology, 2019 Mannan binding lectin (MBL), initially known to activate the complement lectin pathway and defend against infection, was recently shown to be potentially involved in the development of several types of cancer; however, its exact role in cancers ...
Junru Li +11 more
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MASP-1 and MASP-2 Do Not Activate Pro-Factor D in Resting Human Blood, whereas MASP-3 Is a Potential Activator: Kinetic Analysis Involving Specific MASP-1 and MASP-2 Inhibitors. [PDF]
, 2016 It had been thought that complement factor D (FD) is activated at the site of synthesis, and only FD lacking a propeptide is present in blood. The serum of mannose-binding lectin-associated serine protease (MASP)-1/3(-/-) mice contains pro-FD and has ...
Andrea Kocsis +10 more
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Chimerolectins: Classification, structural architecture, and functional perspectives
Protein Science, Volume 34, Issue 9, September 2025.Abstract Lectins are proteins or glycoproteins capable of binding specifically and reversibly to carbohydrates, a property that, in itself, gives them great functional versatility in organisms from all kingdoms of nature. A subclass of these proteins, called chimerolectins, is composed of proteins that have at least one lectin domain associated with ...
Vanir Reis Pinto‐Junior +2 more
wiley +1 more source
Inherited deficiency of the initiator molecules of the lectin-complement pathway [PDF]
, 2010 Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn Skoða/Opna(view/open)The complement system is an important immune system. Its activation results in membranolytic elimination of microbes and opsonization.
Björn Rúnar Lúðvíksson +1 more
core
Lysyl hydroxylase 3 modifies lysine residues to facilitate oligomerization of mannan-binding lectin.
PLoS ONE, 2014 Lysyl hydroxylase 3 (LH3) is a multifunctional protein with lysyl hydroxylase, galactosyltransferase and glucosyltransferase activities. The LH3 has been shown to modify the lysine residues both in collagens and also in some collagenous proteins. In this
Maija Risteli +5 more
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Scientific Reports, 2021 Candida albicans mannan consists of a large repertoire of oligomannosides with different types of mannose linkages and chain lengths, which act as individual epitopes with more or less overlapping antibody specificities. Although anti-C.
Boualem Sendid +13 more
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Multiple Infectious Complications in a Severely Injured Patient with Single Nucleotide Polymorphisms in Important Innate Immune Response Genes [PDF]
, 2015 Trauma is a major public health problem worldwide. Infectious complications, sepsis, and multiple organ dysfunction syndrome (MODS) remain important causes for morbidity and mortality in patients who survive the initial trauma.
Bronkhorst, M.W.G.A. (Maarten) +2 more
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Acta Physiologica, Volume 241, Issue 8, August 2025.ABSTRACT Aim Podocytes, highly specialized epithelial cells located in the glomerulus of the kidney, are essential to the filtration barrier that ensures separation of blood and urine. These cells exhibit a unique architecture, characterized by an intricate network of foot processes interconnected by slit diaphragms, which serve as a critical selective
Desiree Loreth +2 more
wiley +1 more source