Results 71 to 80 of about 4,456 (216)
Scabies mite peritrophins are potential targets of human host innate immunity. [PDF]
PLoS Neglected Tropical Diseases, 2011 BACKGROUND: Pruritic scabies lesions caused by Sarcoptes scabiei burrowing in the stratum corneum of human skin facilitate opportunistic bacterial infections.
Angela Mika +4 more
doaj +1 more source
Análise das variantes polimórficas do éxon 1 do gene que codifica lectina de ligação a manose (MBL2) em pacientes com artrite reumatóide [PDF]
, 2011 Rheumatoid arthritis is an autoimmune disease that operates through joint inflammation becomes chronic over the years and may develop a deformity and destruction of these joints due to erosion of cartilage and bone.
Martiny, Fernanda Letícia
core
Innate immunity and neuroinflammation [PDF]
, 2013 Copyright © 2013 Abhishek Shastri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Bonifati, DM, Kishore, U, Shastri, A
core +3 more sources
Functional Polarization of Liver Macrophages by Glyco Gold Nanoparticles
Advanced Science, Volume 12, Issue 16, April 24, 2025.Macrophages play a critical role in several pathophysiological diseases by being involved in the activation of adaptive and innate immune responses. The repolarization of macrophages using gold nanoparticles functionalized with glycans for a more selective targeting toward a restorative phenotype leads to an amelioration of the events.
Jennifer Fernandez Alarcon +25 more
wiley +1 more source
Frontiers in Immunology, 2021 Thousands of leprosy patients not only suffer from physical deformities, but also either have or have had hepatitis B virus (HBV) coinfection. Polymorphisms of the complement system modulate susceptibility to leprosy, but genetic susceptibility to past ...
Angelica Beate Winter Boldt +15 more
doaj +1 more source
Cholesterol Crystals Activate the Lectin Complement Pathway via Ficolin-2 and Mannose-Binding Lectin: Implications for the Progression of Atherosclerosis. [PDF]
, 2016 Cholesterol crystals (CC) play an essential role in the formation of atherosclerotic plaques. CC activate the classical and the alternative complement pathways, but the role of the lectin pathway is unknown.
Genster, Ninette +4 more
core +1 more source
The chaperone and potential mannan‐binding lectin (MBL) co‐receptor calreticulin interacts with MBL through the binding site for MBL‐associated serine proteases [PDF]
The FEBS Journal, 2008 The chaperone calreticulin has been suggested to function as a C1q and collectin receptor. The interaction of calreticulin with mannan‐binding lectin (MBL) was investigated by solid‐phase binding assays. Calreticulin showed saturable and time‐dependent binding to recombinant MBL, provided that MBL was immobilized on a solid surface or bound to mannan ...
Pagh, Rasmus +9 more
openaire +4 more sources
Advanced Science, Volume 12, Issue 10, March 13, 2025.Immune thrombocytopenia (ITP) is an autoimmune disorder marked by reduced platelet levels and heightened susceptibility to bleeding resulting from augmented autologous platelet destruction and diminished thrombopoiesis. It is found that the lectin pathway of the complement system, resistin, MIF, and AA metabolism may serve as promising targets for ...
Jin Li +21 more
wiley +1 more source
PLoS ONE, 2012 Mannan-binding lectin (MBL), a lectin homologous to C1q, greatly facilitates C3/C4-mediated opsonophagocytosis of Candida albicans (C. albicans) by human neutrophils, and has the capacity to bind to CR1 (CD35) expressed on circulating neutrophils.
Dongsheng Li +10 more
doaj +1 more source
BMC Immunology, 2011 Background Mannan-binding lectin (MBL) is a pattern-recognition molecule present in serum, which is involved in the innate immune defense by activating complement and promoting opsonophagocytosis. Dendritic cells (DCs) are professional antigen presenting
Zhang Liyun +5 more
doaj +1 more source