Results 181 to 190 of about 2,634,020 (215)

Structuring medico-legal autopsy data for public health surveillance using the 11th Revision of the International Classification of Diseases: a retrospective cohort study. [PDF]

Eur J Public Health
Jia Y, Ungermann EM, Feld K, Yen K.
europepmc   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Quantitative systems pharmacology modeling of class I-III BRAF-mutant NSCLC enables subgroup treatment analysis and combination therapy design. [PDF]

iScience
Hu J, Rao Q, Li Z, Li G, Bi Z, Wen D, Zhao C, Zhou G.   +7 more
europepmc   +1 more source

Microbiome-dependent phytosterol sulfates production and tissue distribution in mice. [PDF]

iScience
Tomita K, Nakano T, Morozumi S, Okahashi N, Arita M.   +4 more
europepmc   +1 more source

Expression of concern for Euro Surveill. 2026;31(28).

Euro Surveill
Eurosurveillance editorial team.
europepmc   +1 more source