Results 111 to 120 of about 334,021 (288)

Rapid and Efficient Affinity Isolation of Engineered Extracellular Vesicles Encapsulating Functional Proteins via Internal Twin‐Strep Tetraspanin Tagging

Small, EarlyView.
Structure‐guided internal twin‐Strep tagging of the tetraspanins CD63 or CD9 enables rapid and efficient antibody‐free affinity isolation of engineered extracellular vesicles (EVs) using Strep technology while allowing luminal protein loading. The approach removes over 96% of contaminants, separates tagged EVs from coexisting viral particles, and ...
Minh‐Tu Pham, Jona Benjamin Krohn, Janis Meyer, Christian Ritter, Martin Schneider, Dominic Helm, Dario Frey, Kleopatra Rapti, Uta Haselmann‐Weiss, Elif Toprak, Viet Loan Dao Thi, Florian Leuschner, Dirk Grimm, Karl Rohr, Ralf Bartenschlager   +14 more
wiley   +1 more source

Is There a ‘Cancel Culture’, and if so, for Whom? Rank‐Based Differences in Restrictions on Academic Freedom

The British Journal of Sociology, EarlyView.
ABSTRACT This article investigates the relationship between academic career ranks and restrictions on academic freedom. Drawing on a representative survey of 9083 full‐time academics at German higher education institutions, we examine how academics across different career ranks assess their freedom in teaching and research.
Julian Hamann, Gregor Fabian, Christiane Thompson, Paula‐Irene Villa   +3 more
wiley   +1 more source

Blubber Thickening Driven by UCP1 Inactivation: Insights from a Cetacean‐Like Transgenic Mouse Model

Integrative Zoology, EarlyView.
UCP1 inactivation of cetaceans in mice drives BAT whitening and iWAT hyperplasia, promoting fat accumulation for aquatic adaptation. Abstract Cetaceans possess thick blubber, a specialized adipose tissue essential for thermal insulation, a streamlined body form, energy storage, and buoyancy. However, the mechanisms that underpin this adaptation are not
Qian Zhang, Yuehua Wang, Hang Zhang, Guiping Xu, Shixia Xu, Guang Yang   +5 more
wiley   +1 more source

Sodium Diclofenac‐Loaded Drug Delivery Microspheres: Impact on Calcium Hydroxide Paste Properties and Biological Response

Australian Endodontic Journal, EarlyView.
ABSTRACT This study evaluated whether the incorporation of sodium diclofenac‐loaded microspheres into a calcium hydroxide paste enhances antibiofilm activity while maintaining physicochemical properties and biocompatibility. Calcium hydroxide paste, calcium hydroxide combined with sodium diclofenac, and calcium hydroxide containing sodium diclofenac ...
João Vitor Oliveira de Amorim, Murilo Priori Alcalde, Leonardo Cabau, Rodrigo Ricci Vivan, Paulo Henrique Weckwerth, Marco Antonio Hungaro Duarte, Guilherme Ferreira da Silva   +6 more
wiley   +1 more source

Selective Absence of Co‐Inhibitory Receptor‐Expressing CD4+ T Cells in Lungs of Obese House Dust Mite‐Allergic C57BL/6 Mice

Allergy, EarlyView.
Obesity altered the inflammatory phenotype of HDM‐induced allergic airway inflammation in C57BL/6 mice, indicated by changed BAL cell composition. Single‐cell CITE‐Seq identified the lack of a CD4+ T‐cell subcluster characterized by co‐inhibitory receptor expression in obese HDM‐exposed C57BL/6 mice.
Sarah Miethe, Daniel P. Potaczek, Kim Pauck, Andrea Berlin, Bilal Alashkar Alhamwe, Stefanie Hagner, Andrea Nist, Elke Pogge von Strandmann, Thorsten Stiewe, Paul Klemm, Hartmann Raifer, Clemens Thölken, Holger Garn   +12 more
wiley   +1 more source

Sex differences of in-hospital outcome and long-term mortality in patients with Takotsubo cardiomyopathy

Therapeutics and Clinical Risk Management, 2017
KJ Weidner,1,* I El-Battrawy,1,2,* M Behnes,1 K Schramm,1 C Fastner,1,2 J Kuschyk,1 U Hoffmann,1,2 U Ansari,1 M Borggrefe,1,2 I Akin1,2 1First Department of Medicine, University Medical Centre Mannheim, Faculty of Medicine Mannheim, University of ...
Weidner KJ, El-Battrawy I, Behnes M, Schramm K, Fastner C, Kuschyk J, Hoffmann U, Ansari U, Borggrefe M, Akin I   +9 more
doaj  

Menstrual Cycle and Progesterone-to-Estradiol Ratio Associated With Loss of Control and Craving in Alcohol Use Disorder: A Sex-Segregating Longitudinal Study. [PDF]

Addict Biol
Hoffmann S, Reinhard I, Mühle C, Bach P, Wenger L, Reichert D, Boroumand-Jazi R, Nayman S, Kuehner C, Reichl M, Koopmann A, Beck A, Zech HG, Kornhuber J, Müller CP, Sinha R, Sommer WH, Spanagel R, Banaschewski T, Deserno L, Ebner-Priemer UW, Meyer-Lindenberg A, Rapp MA, Witt SH, Smolka MN, Heinz A, Tost H, Kiefer F, Reichert M, Lenz B, ReCoDe‐Consortium.   +30 more
europepmc   +1 more source

Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy

Andrology, EarlyView.
ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby, Sylvianne Hennebicq, Jacqueline Saias, Florence Brugnon, Isabelle Berthaut, Myriam Daudin, Louis Bujan, Ludovic Dumont, Christine Rondanino, Aurélie Feraille, Nathalie Rives   +10 more
wiley   +1 more source

Galop-Creme Pilo Adolf Krebs Mannheim

GALOP-CREME PILO ADOLF KREBS MANNHEIM Galop-Creme Pilo Adolf Krebs Mannheim ( -
Adolf Krebs Mannheim
core   +1 more source

Correlation of apparent diffusion coefficient, FAP expression in IHC and [⁶⁸Ga]Ga‑FAPI‑46 uptake using integrated PET/MRI in high-grade soft tissue sarcoma: initial exploratory results. [PDF]

EJNMMI Res
Hettler M, Menge F, Ludwig J, Nörenberg D, Schönberg SO, Hinterberger A, Wängler B, Wängler C, Rudolf H, Davarci G, Cieslik P, Cotarelo CL, Harbrücker M, Reißfelder C, Jakob J, Kunz WG, Grawe F.   +16 more
europepmc   +1 more source