Results 121 to 130 of about 416,662 (279)

TET3‐Mediated m5C Modification of CCAT2 Accelerates Cardiac Microvascular Endothelial Cell Damage in Acute Coronary Syndrome

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Acute coronary syndrome (ACS) is a clinical syndrome involving myocardial ischemia. This study aimed to elucidate the mechanism of TET3 in ACS‐induced CMEC damage, thereby identifying a new target for ACS treatment. The expression of TET3 in ACS patients and healthy subjects was analyzed.
Jun‐Cheng Liu   +5 more
wiley   +1 more source

Forsythiaside A Alleviates Kidney Injury and Intestinal Epithelium Dysfunction in IgA Nephropathy by Inhibiting TLR4/NF‐κB Signaling

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT IgA nephropathy (IgAN), the most common form of glomerulonephritis, is a major and growing public health issue. It results from intestinal barrier dysfunction that leads to mesangial deposition of pathogenic galactose‐deficient IgA1 (Gd‐IgA1) and renal inflammation.
Meng‐Si Li, Kai Liu
wiley   +1 more source

Sex differences of in-hospital outcome and long-term mortality in patients with Takotsubo cardiomyopathy

open access: yesTherapeutics and Clinical Risk Management, 2017
KJ Weidner,1,* I El-Battrawy,1,2,* M Behnes,1 K Schramm,1 C Fastner,1,2 J Kuschyk,1 U Hoffmann,1,2 U Ansari,1 M Borggrefe,1,2 I Akin1,2 1First Department of Medicine, University Medical Centre Mannheim, Faculty of Medicine Mannheim, University of ...
Weidner KJ   +9 more
doaj  

PRDM1 Knockdown Promotes Ferroptosis and Sunitinib Sensitivity by Modulating the PI3K/Akt Signaling Through Inhibition of ESM1 Transcription in Renal Cell Carcinoma

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Renal cell carcinoma (RCC) is a commonly occurring and considerable burden on public health. Although chemotherapy benefits patients with advanced RCC, sunitinib resistance leads to a poor prognosis. Ferroptosis is also involved in sunitinib resistance in RCC.
Yi‐Shuai Zhang   +5 more
wiley   +1 more source

Age at the time of surgery does not compromise the outcome of deepening trochleoplasty: Results from under and over 30 years old

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This study aimed to evaluate whether age at the time of surgery influences patient‐reported outcome measures (PROMs) in patients undergoing tailored surgical treatment for lateral patellar dislocation (LPD), including deepening trochleoplasty (TP). Methods This retrospective cohort study used a prospectively maintained database.
Danko Dan Milinkovic   +4 more
wiley   +1 more source

Diagnostic value of the patellar tendon–lateral trochlear ridge distance and the patellar tendon–trochlear groove angle in differentiating lateral patellar instability from malalignment‐induced patellofemoral pain

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To compare the patellar tendon–lateral trochlear ridge (PT‐LTR) distance and patellar tendon–trochlear groove angle (PT‐TGA) between patients with lateral patellar instability (LPI) and those with malalignment‐induced patellofemoral pain (PFP), and to evaluate their differential diagnostic validity.
Razvan Pacala   +5 more
wiley   +1 more source

CNDP1 (CTG)<sub>5</sub> allele and cardiovascular events in high-risk patients: LURIC study results. [PDF]

open access: yesSci Rep
Hettler SA   +7 more
europepmc   +1 more source

Hallux Valgus and Associated Foot Pathology in Ancient Egyptian Mummies: A Qualitative and Quantitative Computed Tomography Study

open access: yesInternational Journal of Osteoarchaeology, EarlyView.
ABSTRACT The aim of this study was to gain information on the prevalence and manifestation of hallux valgus and associated foot pathology in ancient Egyptian mummies. Additionally, we investigated possible indicators of postmortem deformation of the feet during mummification. For this study, 34 mummies that had undergone whole body computed tomography (
Stephanie Panzer   +7 more
wiley   +1 more source

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