Results 141 to 150 of about 416,662 (279)

ALTER Mannheim

, 2023
Anna Blaich, Felix Grädler, Henning Mohr, Hannes Seibold   +3 more
openaire   +1 more source

Tributyltin Protumorigenic Effects Targeting Prostate Cancer Cell Metabolism, Proliferation, Migration, and Invasion

Environmental Toxicology, EarlyView.
ABSTRACT Prostate cancer (PCa) is an endocrine‐related cancer highly dependent on androgenic signaling. Beyond hormone dependence, extrinsic factors play a significant role in the risk of developing PCa, which raises concern about the influence of environmental compounds such as endocrine‐disrupting chemicals (EDCs). Tributyltin (TBT) is an EDC used in
Mariana Feijó, Luís P. Brás, Catarina M. D. Serra, Lara R. S. Fonseca, Sara Correia, Bruno J. Pereira, Ana P. Duarte, Henrique J. Cardoso, Cátia V. Vaz, Sílvia Socorro   +9 more
wiley   +1 more source

Monocytes acquire a tumor-associated IL1B program upon encountering patient-derived colon cancer organoids. [PDF]

Oncoimmunology
Balzasch BM, von Kries A, Hüll S, Shaltiel IA, Boonekamp KE, Ast V, Burgermeister E, Betge J, Ebert M, Boutros M, Helming L, Umansky V, Cerwenka A.   +12 more
europepmc   +1 more source

Variation on Toxic and Inflammatory Potential of Coal Smoke of Different Sources From a Region With High Lung Cancer Risk

Environmental Toxicology, EarlyView.
ABSTRACT Excess lung cancer risk in Xuanwei and Fuyuan, China, has been attributed to household air pollution from use of a locally sourced smoky (bituminous) coal. However, the carcinogenic mechanisms remain unclear. Given the important role of inflammation in lung cancer development, this study compared the proinflammatory potentials of the ...
Yongliang Zhang, Wei Hu, Nathanial Rothman, Dingyu Liu, Jihua Li, Jun Xu, Bofu Ning, Roel Vermeulen, Qing Lan, Flemming R. Cassee, George S. Downward   +10 more
wiley   +1 more source

Hemodynamic effects of red blood cell transfusion in patients with hemato-oncologic diseases. [PDF]

Front Med (Lausanne)
Yazdani B, Schneider N, Abba M, Schulz M, Schumacher G, Yuecel G, Hofheinz RD, Duerschmied D, Kayser S, Hohneck A.   +9 more
europepmc   +1 more source

Chrysin Mitigates Acetamiprid‐Induced Testicular Injury in Mice via Suppression of Endoplasmic Reticulum Stress and Inflammation

Environmental Toxicology, EarlyView.
ABSTRACT Acetamiprid (ACP) is a neonicotinoid pesticide that is extensively utilized for the management of insect populations, but its toxic effects on the male reproductive system have become a source of concern. Chrysin (CHR) is a natural flavone found in many plants and bee products, including honey and propolis.
Selim Demir, Nihal Turkmen Alemdar, Esin Yulug, Ali Kulaber, Elif Ayazoglu Demir, Nadire Sevdenur Erdogan, Ahmet Mentese, Yuksel Aliyazicioglu   +7 more
wiley   +1 more source

Decreased Tissue Sodium Concentration in Suspected Prostate Cancer Detected by Internal-Reference ²³Na MRI: A Prospective Exploratory Study. [PDF]

Diagnostics (Basel)
Adlung A, Westhoff N, Hausmann D, Schoenberg SO, Nörenberg D, Zöllner FG, Tollens F.   +6 more
europepmc   +1 more source

Prenatal Environmental Hypoxia Enhances Adult Hypoxia Tolerance in Brandt's Voles (Lasiopodomys brandtii): Behavioral and Transcriptomic Insights

Integrative Zoology, EarlyView.
Prenatal hypoxia enhances adult hypoxia tolerance in Brandt's voles, preserving cognitive and memory functions. Transcriptomic analysis reveals adaptive changes in energy metabolism, oxygen transport, and neuroprotective mechanisms, highlighting developmental plasticity.
Mengyang Li, Congcong Qiao, Xiujuan Li, Maolin Huang, Zhenlong Wang, Luye Shi   +5 more
wiley   +1 more source

Somatic gene mutations in the motor cortex of patients with sporadic amyotrophic lateral sclerosis. [PDF]

Brain
González-Velasco Ó, Parlato R, Yilmaz R, Decker L, Menge S, Freischmidt A, Yang X, Tulasi N, Brenner D, Andersen PM, Forsberg KME, Schlachetzki JCM, Brors B, Voith von Voithenberg L, Weishaupt JH.   +14 more
europepmc   +1 more source

Blubber Thickening Driven by UCP1 Inactivation: Insights from a Cetacean‐Like Transgenic Mouse Model

Integrative Zoology, EarlyView.
UCP1 inactivation of cetaceans in mice drives BAT whitening and iWAT hyperplasia, promoting fat accumulation for aquatic adaptation. Abstract Cetaceans possess thick blubber, a specialized adipose tissue essential for thermal insulation, a streamlined body form, energy storage, and buoyancy. However, the mechanisms that underpin this adaptation are not
Qian Zhang, Yuehua Wang, Hang Zhang, Guiping Xu, Shixia Xu, Guang Yang   +5 more
wiley   +1 more source