Results 21 to 30 of about 171,463 (293)
Ideologinė ir sociologinė dvasinių darinių interpretacija
Publikacijoje nagrinėjamas idėjos ir ideologijos santykis, sociologinės interpretacijos problema, išskiriami jos tipai. Teigiama, kad sociologinis požiūris į dvasinius turinius yra ypatingas idėjų išorinio nagrinėjimo būdas.
Karl Mannheim
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Mannheim szerint (Mannheim 1969) egy korcsoport akkor tekinthető generációnak, ha valamely közös immanens tulajdonság, nemzedéki tudat, közösségi jegy jellemzi őket, s ehhez három feltétel szükséges: a közös tapasztalat (élmény); a tényleges egymásra ...
Ádám Nagy, Attila Kölcsey
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Mannheim Offsets of Ruled Surfaces [PDF]
In a recent works Liu and Wang (2008; 2007) study the Mannheim partner curves in the three dimensional space. In this paper, we extend the theory of the Mannheim curves to ruled surfaces and define two ruled surfaces which are offset in the sense of Mannheim.
Orbay, Keziban +2 more
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β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Time of Protest: Multi-temporality as an Attribute of the Relations of Power and Resistance
The article examines how the perception of historical time influences the dynamics of power relations and resistance. It draws on the concept of multitemporality, which posits that different 'temporal regimes' — different experiences of time and ...
A. P. Golubeva
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Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr +5 more
wiley +1 more source
Mannheim Curves in Nonflat 3-Dimensional Space Forms
We consider the Mannheim curves in nonflat 3-dimensional space forms (Riemannian or Lorentzian) and we give the concept of Mannheim curves. In addition, we investigate the properties of nonnull Mannheim curves and their partner curves.
Wenjing Zhao, Donghe Pei, Xinyu Cao
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Sternbedeckungen in Mannheim beobachtet [PDF]
n ...
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