Results 51 to 60 of about 173,926 (294)

From Sample to Mixed Reality: A Translational 3D MALDI Imaging Platform for Advanced 3D Spatial Omics Analysis of 3D Cell Culture Disease Models

open access: yesAdvanced Science, EarlyView.
A comprehensive technology platform enables high‐fidelity, volumetric MALDI imaging of 3D cell cultures by integrating custom embedding molds, a semi‐automated computational framework for 3D reconstruction, voxel‐instead of pixel‐based biomarker discovery, and immersive mixed reality data exploration.
Stefania Alexandra Iakab   +16 more
wiley   +1 more source

Mannheim B-Curves in the Euclidean 3-Space E^3

open access: yesKuwait Journal of Science, 2017
In this study we have defined Mannheim curves according to a Bishop frame and called Mannheim B-curves in the Euclidean 3-space E^3. Then the relations have been found between the Bishop and Frenet vectors of these curves and some conditions have been ...
Melek Masal, Ayse Z. Azak
doaj  

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

open access: yesAdvanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang   +15 more
wiley   +1 more source

Pan2‐Pan3 Complex‐Mediated Deadenylation Enforces mRNA Quality Control for Infection of the Rice Blast Fungus

open access: yesAdvanced Science, EarlyView.
Discovery that deadenylation, rather than transcription, acts as the rate‐limiting step for developmental timing in a plant pathogen. Evidence that P‐body integrity and mRNA decay are mechanistically coupled to rapid cellular differentiation under environmental stress. Identification of Pan2‐Pan3 as a pathogen‐specific “meta‐virulence factor” absent in
Ziwei Lv   +6 more
wiley   +1 more source

Genetic Control of Tissue Remodeling by a Non‐Coding SNP in ITGA8 Explains Carotenoid‐Based Color Polymorphism in Marine Mollusks

open access: yesAdvanced Science, EarlyView.
In this study, the orange‐muscle giant abalone (Haliotis gigantea) is used as a model to identify a non‐coding SNP that disrupts the interaction between ITGA8 pre‐mRNA and the splicing factor ILF2, leading to altered ITGA8 splicing. These splicing changes promote carotenoid accumulation in abalone muscle through the regulation of tissue remodeling ...
Xiaohui Wei   +17 more
wiley   +1 more source

La historicidad de imágenes oníricas quechuas sudperuanas

open access: yesLetras, 2015
Las imágenes semióticas están enlazadas a sus modos de interpretación y siempre, de una forma específica, a una cultura. Para este estudio usamos la descripción de la interpretación de sueños quechuas sudperuanos presente en el Ritual formulario de Pérez
Bruce Mannheim
doaj  

Anomalous dimensions and the renormalizability of the four-fermion interaction

open access: yesPhysics Letters B, 2017
We show that when the dynamical dimension of the ψ¯ψ operator is reduced from three to two in a fermion electrodynamics with scaling, a g(ψ¯ψ)2+g(ψ¯iγ5ψ)2 four-fermion interaction which is dressed by this electrodynamics becomes renormalizable.
Philip D. Mannheim
doaj   +1 more source

Bistable Dual‐Responsive Azobenzene‐co‐PNIPAM Soft Microactuators via Two‐Photon Direct Laser Writing

open access: yesAdvanced Intelligent Systems, EarlyView.
This work shows the successful integration of intrinsic bistability into thermoresponsive soft microactuators, fabricated by two‐photon polymerization utilizing the (E)–(Z)‐isomerization of azobenzenes. The bistable behavior accounts for a reversible volume change of Azo_pNIPAM microactuators initiated by light irradiation, at constant ambient ...
Chantal Barwig   +13 more
wiley   +1 more source

Modelling the Incremental Value of Personality Facets: The Domains‐Incremental Facets‐Acquiescence Bifactor Model

open access: yesEuropean Journal of Personality, EarlyView., 2020
Abstract Personality can be described at different levels of abstraction. Whereas the Big Five domains are the dominant level of analysis, several researchers have called for more fine‐grained approaches, such as facet‐level analysis. Personality facets allow more comprehensive descriptions, more accurate predictions of outcomes, and a better ...
Daniel Danner   +4 more
wiley   +1 more source

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