Results 51 to 60 of about 334,021 (288)

SPRED2 Negatively Regulates CD8+ T Cell‐Mediated Antitumor Immunity in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Sprouty‑related EVH1 domain containing 2 (SPRED2) restrains Ras/Raf/ERK signaling in CD8+ T cells. Host SPRED2 deficiency enhances T‐cell survival, cytotoxicity, and memory‐like phenotypes, reducing primary tumor growth and endpoint lung metastatic burden in breast cancer models.
Miao Tian   +8 more
wiley   +1 more source

A ROS‐Responsive and Mucoadhesive Thermosensitive Hydrogel Encapsulated with Mizoribine for Synergistic Dry Eye Therapy

open access: yesAdvanced Science, EarlyView.
The ROS‐responsive in situ thermosensitive MZR@SPPP hydrogel system enables dual‐stage drug loading and sustained ocular delivery. Upon administration, it gelates at ocular surface temperature, enhancing ocular adhesion. By scavenging free radicals, restoring NRF2‐mediated antioxidant defense and mitochondrial homeostasis, and suppressing inflammatory ...
Danyi Qin   +13 more
wiley   +1 more source

Mannheim, Germany 1961

open access: yes, 1961
Cover title: Mannheim, Amtlicher Stadtplan.; Inset: Ubersichtskarte Mannheim und Umgebung i. M., 1:300,000.; Accompanied by: Stadt Mannheim Strassenverzeichnis zum Amtlichen Stadtplan.

core  

Spatially Informed Feature Selection and Machine Learning in Matrix‐Assisted Laser Desorption/Ionization Imaging for Cohort‐Scale Molecular Tissue Phenomics in Glioblastoma

open access: yesAdvanced Intelligent Discovery, EarlyView.
Matrix‐assisted laser desorption/ionization imaging‐based identification of reliable small molecule markers across heterogeneous glioblastoma cohorts is challenging with intensity‐only methods. We present spatially informed feature selection (SIFS), a spatially informed framework that prioritizes molecules consistently colocalizing with histopathology.
Shad A. Mohammed   +15 more
wiley   +1 more source

Mannheim, Germany 1949

open access: yes, 1949
North oriented to the upper left. Accompanied by index: "Mannheimer Strassenverzeichnis mit Angabe des Stadtteils und der Planlage im Haupt u. Beiplan der Stadt Mannheim Ausgabe 1949." "Jan.
Mannheim (Germany). Städt-Vermessungsamt
core  

Behaviorally Adaptive and Inclusive Advanced Driver‐Assistance Systems

open access: yesAdvanced Intelligent Systems, EarlyView.
Advanced driver‐assistance systems (ADASs) are mapped as evolving human‐centered, adaptive technologies linking sensing, driver monitoring, AR/HUD interfaces, patents, regulation, and inclusive design. The review identifies gaps in real‐world evidence, diverse‐driver validation, gaze metrics, and governance, outlining a roadmap for safer, behaviorally ...
Jana Skirnewskaja   +2 more
wiley   +1 more source

Mannheim B-Curves in the Euclidean 3-Space E^3

open access: yesKuwait Journal of Science, 2017
In this study we have defined Mannheim curves according to a Bishop frame and called Mannheim B-curves in the Euclidean 3-space E^3. Then the relations have been found between the Bishop and Frenet vectors of these curves and some conditions have been ...
Melek Masal, Ayse Z. Azak
doaj  

Preoperative Sagittal Tibial Tubercle‐Trochlear Groove Distance Predicts Postoperative Outcome in Patients Undergoing Combined Trochleoplasty and Medial Patellofemoral Ligament Reconstruction

open access: yesArthroscopy, EarlyView.
Purpose To evaluate the association between the preoperative sagittal tibial tubercle‐trochlear groove (sTTTG) distance and postoperative patient‐reported outcomes after combined patellofemoral ligament reconstruction and deepening trochleoplasty in patients with recurrent lateral patellar instability and high‐grade trochlear dysplasia.
Sebastian Schmidt   +5 more
wiley   +1 more source

Modelling the Incremental Value of Personality Facets: The Domains‐Incremental Facets‐Acquiescence Bifactor Model

open access: yesEuropean Journal of Personality, EarlyView., 2020
Abstract Personality can be described at different levels of abstraction. Whereas the Big Five domains are the dominant level of analysis, several researchers have called for more fine‐grained approaches, such as facet‐level analysis. Personality facets allow more comprehensive descriptions, more accurate predictions of outcomes, and a better ...
Daniel Danner   +4 more
wiley   +1 more source

Heftsche Kunstmühle A.G. Mannheim

open access: yes
HEFTSCHE KUNSTMÜHLE A.G. MANNHEIM Heftsche Kunstmühle A.G. Mannheim ( -
Heftsche Kunstmühle A.G. Mannheim
core   +3 more sources

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