Results 191 to 200 of about 61,569 (245)

Preterm Birth Increases Susceptibility to Hyperglycemia‐Induced Kidney Injury With Sex‐Specific Differences in Structural and Molecular Responses

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 3, May 2026.
Preterm mice were delivered at 19 dpc and rendered diabetic with STZ at 6 weeks; kidneys were analysed at 18 weeks. PT‐D females showed increased atubular glomeruli, reduced proximal tubule fraction, higher albuminuria and BUN, and dysregulated fibrotic, vascular, mitochondrial, and Notch pathways.
Rachel K. Dailey, Aleksandra Cwiek, Logan C. Hamil, Sage Timberline, Ayyappa Kumar Sista Kameshwar, Masako Suzuki, Jaya Isaac, Kimberly deRonde, Mark Conaway, Kevin M. Bennett, Edwin J. Baldelomar, Matthew R. Hoch, Kimberly J. Reidy, Jennifer R. Charlton   +13 more
wiley   +1 more source

Prognostic potential of circulatory miR-19a-3p, miR-19b-3p, and miR-329-3p for future hypertension diagnosis. [PDF]

J Hypertens
Kostiniuk D, Blankenstein A, Rajić S, Ciantar J, Mononen N, Lyytikäinen LP, Seppälä I, Mishra PP, Juonala M, Waldenberger M, Elovainio M, Oksala N, Kähönen M, Hutri N, Raitakari O, Kleber ME, März W, Lehtimäki T, Marttila S, Raitoharju E.   +19 more
europepmc   +1 more source

Conditioned Pain Modulation Inter‐Site Variability Study: Effect Sizes and Test–Retest Reliability of Two Models

European Journal of Pain, Volume 30, Issue 5, May 2026.
ABSTRACT Background Conditioned pain modulation (CPM) is a set of psychophysical paradigms that is increasingly used clinically to evaluate descending pain modulation pathways. Impairment is common in chronic pain, suggesting CPM may serve as a mechanistic indicator. However, the lack of protocol standardization and reference data prevents clinical use
Yi‐Wun Lin, Hannah Schmidt, Niko Möller‐Grell, Walter Magerl, Li‐Ling Hope Pan, Shuu‐Jiun Wang, Li‐Wei Chou, Rolf‐Detlef Treede   +7 more
wiley   +1 more source

Quantitative PCCT imaging in differentiating adrenal adenomas from metastases: diagnostic performance and its clinical applications. [PDF]

Abdom Radiol (NY)
Haag F, Emmrich SS, Hertel A, Rink J, Vellala A, Komlen S, Nörenberg D, Schoenberg SO, Froelich MF.   +8 more
europepmc   +1 more source

Fucoxanthin Ameliorates MASLD by Directly Targeting GRP78 to Restore ER Homeostasis and Activate AMPK Signaling

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Proposed model of fucoxanthin in ameliorating MASLD via the GRP78‐AMPK axis. In MASLD, excessive lipid accumulation (FFA, TG, DNL) leads to ER stress activation (upregulation of CHOP, ATF6, IRE1) and GRP78 dysfunction, promoting hepatic lipid droplet (LD) formation. Fucoxanthin directly binds to GRP78, which in turn activates AMPK signaling.
Lin Zhang, Ruifen Zhang, Yu Wu, Binbin Chen, Chao Wang, Cheng Wang, Zhengshun Wen, Jingui Zhang, Haibin Tong, Liang Hong   +9 more
wiley   +1 more source

A pipeline of machine learning-driven multi-modal data fusion methods for prognostic risk analysis in bevacizumab-treated metastatic colorectal cancer. [PDF]

Sci Rep
Thomas V, Nyamundanda G, Lärkeryd A, Hari PS, Miller IS, Venken T, Smeets D, Boeckx B, Betge J, Ebert MPA, Gaiser T, Murphy V, Kay E, Verheul HM, O'Farrell AC, Cremolini C, Marmorino F, Gallagher WM, Barat A, Klinger R, Fender B, Ylstra B, van Grieken N, McNamara DA, Hennessy BT, Das S, Moran B, O'Connor DP, Dienstmann R, Lambrechts D, Prehn JHM, Sadanandam A, Byrne AT.   +32 more
europepmc   +1 more source

Diagnostic Value of Neutrophil‐to‐Lymphocyte Ratio and Mean Platelet Volume as Predictors of Liver Fibrosis Severity in MASLD: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Introduction Metabolic dysfunction‐associated steatotic liver disease (MASLD) has become a leading cause of chronic liver disease worldwide, yet simple and reliable non‐invasive markers for fibrosis assessment remain limited. Accessible blood‐based indicators could aid early detection of significant fibrosis.
Ghannei Olfa, Olfa Lataoui, Sefrihi Fatima Ezzahra, Ben Amor Soumaya, Trimech Mayada   +4 more
wiley   +1 more source

The Influence of Reaming Velocity During Preparation of the Femoral Canal-An In Vitro Analysis of Two Straight Femoral Revision Stems with a Fluted Tapered Design. [PDF]

Bioengineering (Basel)
Bischel OE, Seeger JB, Jung MK, Dörfler S, Höppchen AJ, Jahnke A, Jakubowitz E.   +6 more
europepmc   +1 more source

Expanding Access to Early Diabetes Detection: A Pharmacy‐Based Screening Pilot in Rural New South Wales

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Type 2 diabetes mellitus remains a major public health challenge in Australia. This cross‐sectional pilot feasibility study evaluated the feasibility of pharmacy‐led diabetes screening in rural New South Wales and examined diabetes knowledge, AUSDRISK, and follow‐up behavior after referral.
Osuagwu Levi Uchechukwu, Ross Wilson, Kingsley Agho, David Simmons, Krista Reed, Eme Eseme John, Siddarth Sethi, Peter Simmons   +7 more
wiley   +1 more source

Stereotactic body radiotherapy for spine and non-spine bone metastases in prostate carcinoma - a multicenter cohort analysis. [PDF]

J Bone Oncol
Nägler F, Seiler I, Schäfer S, Meents J, Lohaus F, Grün A, Wittenstein O, Klischies K, Remmele J, Rühle A, Eckl M, Blanck O, Boda-Heggemann J, Giordano FA, Moustakis C, Nicolay NH, Kästner L.   +16 more
europepmc   +1 more source