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Probing enzymatic properties of N-glycosyltransferase isoforms from Mannheimia haemolytica

Carbohydrate Research, 2023
N-Glycosyltransferase (NGT) is an inverting glycosyltransferase for an unusual pathway of N-linked protein glycosylation and glycosylates polypeptides in the consensus sequon (N-(X≠P)-T/S) with hexose monosaccharides. Here, we expressed and characterized a novel N-glycosyltransferase from Mannheimia haemolytica (named MhNGT).
Zhaoxi, Liu   +3 more
openaire   +2 more sources

Phenotypic antibiotic resistance prediction using antibiotic resistance genes and machine learning models in Mannheimia haemolytica.

Veterinary Microbiology
Mannheimia haemolytica is one of the most common causative agents of bovine respiratory disease (BRD); however, antibiotic resistance in this species is increasing, making treatment more difficult.
Carmen L. Wickware   +3 more
semanticscholar   +1 more source

Antibiogram use on dairy cattle for bovine respiratory disease: Multidrug resistance in Pasteurella multocida and Mannheimia haemolytica in California dairies.

Journal of Dairy Science
Multidrug-resistant (MDR) bovine respiratory pathogens can significantly decrease treatment success and have an effect on dairy farm productivity. Although antibiograms have emerged as a tool to support empirical decision making for disease treatment ...
Hugo F Monteiro   +9 more
semanticscholar   +1 more source

Experimental infection of Peste des Petit Ruminant virus and Mannheimia haemolytica A2 in goats: immunolocalisation of Mannheimia haemolytica antigens

Veterinary Research Communications, 2010
Nigerian strain of Peste des Petit Ruminant (PPR) virus and Mannheimia haemolytica (MH) biotype A serotype 2, was used successfully to reproduce a concurrent disease in West African Dwarf goats. The development of the various pathological features were studied at regular intervals following infection. The acute inflammatory reaction which had developed
Obukowho Emikpe, Benjamin   +3 more
openaire   +3 more sources

Mannheimia haemolytica and respiratory complex diseases in calves

Practica Veterinara.ro, 2023
Mannheimia haemolytica, formerly known as Pasteurella haemolytica, is a bacterium belonging to the family Pasteurellaceae. It is commonly found in the respiratory tracts of cattle and other ruminant animals, and is a significant pathogen in the cattle industry.
Mario-Darius Codreanu   +3 more
openaire   +1 more source

Mannheimia haemolytica OmpH binds fibrinogen and fibronectin and participates in biofilm formation.

Microbial Pathogenesis, 2022
Mannheimia haemolytica is the causal agent of the shipping fever in bovines and produces high economic losses worldwide. This bacterium possesses different virulence attributes to achieve a successful infection.
Cecilia Figueroa-Valenzuela   +5 more
semanticscholar   +1 more source

A multiplex polymerase chain reaction assay for the identification of Mannheimia haemolytica, Mannheimia glucosida and Mannheimia ruminalis

Veterinary Microbiology, 2008
The objective of this study was to design a multiplex PCR assay to identify Mannheimia haemolytica, Mannheimia glucosida and Mannheimia ruminalis. The multiplex PCR included primer sets HP, amplifying a DNA region from an unknown hypothetical protein, Lkt and Lkt2, amplifying different regions of the leukotoxinD gene, and 16S to amplify universal ...
Trevor W, Alexander   +7 more
openaire   +2 more sources

Mannheimia haemolytica leukotoxin

2010
Mannheimia haemolytica is the primary bacterial pathogen of bovine pneumonic pasteurellosis, an economically important disease of cattle worldwide. Leukotoxin (Lkt) produced by M. haemolytica is the major virulence factor of this organism. The cytolytic activity of Lkt is specific for ruminant leukocytes.
openaire   +2 more sources

Molecular genetic analysis of virulence in Mannheimia pasteurella haemolytica

Frontiers in Bioscience, 2001
Mannheimia haemolytica (previously known as Pasteurella haemolytica) is a weakly hemolytic, gram-negative coccobacillus that is an opportunistic pathogen of cattle, sheep and other ruminants. In stressed, immunocompromised animals, the organism causes a fibrinous, necrotic pneumonia, commonly called "shipping fever".
openaire   +2 more sources

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