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Influence of mannitol concentration on the physicochemical, mechanical and pharmaceutical properties of lyophilised mannitol

open access: yesInternational Journal of Pharmaceutics, 2016
Mannitol is a pharmaceutical excipient that is receiving increased popularity in solid dosage forms. The aim of this study was to provide comparative evaluation on the effect of mannitol concentration on the physicochemical, mechanical, and ...
Waseem Kaialy
exaly   +2 more sources
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A Comparative Study of Bolus Dose of Hypertonic Saline, Mannitol, and Mannitol Plus Glycerol Combination in Patients with Severe Traumatic Brain Injury.

World Neurosurgery, 2019
BACKGROUND This prospective randomized controlled study compared the efficacy of an equiosmolar and isovolumetric dose of 3% hypertonic saline, 20% mannitol, and 10% mannitol plus 10% glycerol combination in reducing the raised intracranial pressure (ICP)
Harshad Patil, Rakesh K. Gupta
semanticscholar   +1 more source

Impact of fast and conservative freeze‐drying on product quality of protein‐mannitol‐sucrose‐glycerol lyophilizates

European journal of pharmaceutics and biopharmaceutics, 2018
Graphical abstract Figure. No caption available. Purpose: Mannitol/sucrose formulations are employed to generate lyophilizates for biopharmaceuticals with an elegant cake appearance.
Jacqueline Horn   +2 more
semanticscholar   +1 more source

Mechanisms by which crystalline mannitol improves the reconstitution time of high concentration lyophilized protein formulations

European journal of pharmaceutics and biopharmaceutics, 2018
Graphical abstract Figure. No caption available. ABSTRACT Lyophilized high concentration protein formulations often have long and variable reconstitution times. The aim is to understand the role of crystalline mannitol in lowering the reconstitution time
Shreya S. Kulkarni   +3 more
semanticscholar   +1 more source

Characterization of mannitol granules and powder: A comparative study using two flowability testers

International journal of pharmaceutics, 2018
Graphical abstract Figure. No caption available. ABSTRACT In the manufacture of tablets, especially in direct tableting processes, the flowability of excipient powders and formulated powders is one of the most important characteristics.
Y. Takeuchi   +7 more
semanticscholar   +1 more source

Mannitol Production by Heterofermentative Lactic Acid Bacteria: a Review

Applied Biochemistry and Biotechnology, 2022
J. Martínez-Miranda   +2 more
semanticscholar   +1 more source

Mannitol

Reactions Weekly, 2007
S.J. Enna, David B. Bylund
  +5 more sources

Mannitol

Reactions weekly, 2020

semanticscholar   +1 more source

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