Results 101 to 110 of about 63,187 (317)

Diacetylene‐Functionalized Glycan Mimetics for Receptor‐Mediated Cluster Imprinting in Model Membranes

Macromolecular Rapid Communications, EarlyView.
Diacetylene‐containing glycan mimetics cluster upon selective lectin binding in GUVs. Subsequent irradiation leads to the formation of fluorescent polymer clusters, while non‐clustered glycan mimetics remain unaffected in the membrane. ABSTRACT The glycocalyx, a dense layer of glycoproteins and glycolipids on eukaryotic cells, is essential for cellular
Luca‐Cesare Blawitzki, Lina Charlotte Assenmacher, Nicholas Jäck, Stephan Schmidt, Cornelia Monzel, Laura Hartmann   +5 more
wiley   +1 more source

Lectins from the Edible Mushroom Agaricus bisporus and Their Therapeutic Potentials

Molecules, 2020
The mushroom Agaricus bisporus secretes biologically active compounds and proteins with benefits for human health. Most reported proteins from A. bisporus are tyrosinases and lectins. Lectins are of therapeutic or pharmaceutical interest.
Wangsa Tirta Ismaya, Raymond Rubianto Tjandrawinata, Heni Rachmawati   +2 more
doaj   +1 more source

Lectins and Tetrahymena – A review [PDF]

, 2016
The unicellular ciliate Tetrahymena is a complete organism, one of the most highly developed protozoans, which has specialized organelles performing each of the functions characteristic to the cells of higher ranked animals.
Csaba, György
core   +1 more source

Protein glycosylation in lung cancer from a mass spectrometry perspective

Mass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi, Simon Sugár, Lilla Turiák   +2 more
wiley   +1 more source

Molecular recognition of surface-immobilized carbohydrates by a synthetic lectin

Beilstein Journal of Organic Chemistry, 2014
The molecular recognition of carbohydrates and proteins mediates a wide range of physiological processes and the development of synthetic carbohydrate receptors (“synthetic lectins”) constitutes a key advance in biomedical technology.
Melanie Rauschenberg, Eva-Corrina Fritz, Christian Schulz, Tobias Kaufmann, Bart Jan Ravoo   +4 more
doaj   +1 more source

Structural basis for disparate sugar-binding specificities in the homologous cargo receptors ERGIC-53 and VIP36. [PDF]

PLoS ONE, 2014
ERGIC-53 and VIP36 are categorized as leguminous type (L-type) lectins, and they function as cargo receptors for trafficking certain N-linked glycoproteins in the secretory pathway in animal cells. They share structural similarities in their carbohydrate
Tadashi Satoh, Kousuke Suzuki, Takumi Yamaguchi, Koichi Kato   +3 more
doaj   +1 more source

Evolution and Immune Function of Fish Lectins [PDF]

, 2016
Lectins are sugar-binding proteins widely distributed among animals, plants, and microbial taxon, involved in diverse biological processes. In both invertebrates and vertebrates, they play key roles in nonself recognition and immune responses, such as ...
Ahmad, Ahmed, Ahmed, Arason, Argayosa, Ballarin, Bianchet, Bianchet, Brewer, Cammarata, Cammarata, Cammarata, Cammarata, Cammarata, Camus, Casadevall, Chen, Cooper, Earl, Eddie, Ewart, Fujita, Gabius, Garner, Gonzalez, Hernandez, Hirabayashi, Honda, Hosono, Houzelstein, Inagawa, Jackson, Jia, Jimbo, Kaltner, Kania, Kilpatrick, Kondo, Lam, Levroney, Liao, Liu, Lopez, Loris, Matsui, Mitra, Muramoto, Nakao, Nikolakopoulou, Nitta, Noguchi, Odom, Ogawa, Ottinger, Ourth, Ozeki, Pan, Parisi, Paulson, Qiu, Rabinovich, Russel, Salerno, Sato, Schwarz, Sharon, Sharon, Shiina, Shirai, Silva, Takahashi, Tasumi, Tateno, Tateno, Tateno, Teichberg, Terada, Thongda, Tsutsui, Tsutsui, Tsutsui, Turner, Vakonakis, Vasta, Vasta, Vasta, Vasta, Vasta, Vasta, Vasta, Vitved, Watanabe, Watkins, Yano, Zelensky, Zhang   +95 more
core   +1 more source

Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances

Mass Spectrometry Reviews, EarlyView.
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley   +1 more source

Horizontal gene transfer contributed to the evolution of extracellular surface structures [PDF]

, 2012
The single-cell layered ectoderm of the fresh water polyp Hydra fulfills the function of an epidermis by protecting the animals from the surrounding medium.
Altstätter, Johannes, Böttger, Angelika, David, Charles N., Deutzmann, Rainer, Doxey, Andrew C., Gabius, Hans-Joachim, Geissner, Andreas, Heim, Astrid, Hess, Michael W., McConkey, Brendan J., Münder, Sandra, Pauly, Barbara, Pfaller, Kristian, Salvenmoser, Willi   +13 more
core   +1 more source

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui, Elena N. Kitova, Ling Han, Lara K. Mahal, John S. Klassen   +4 more
wiley   +1 more source