Results 131 to 140 of about 25,372 (246)

Engagement of a Neighboring Lys Residue by a Salicylaldehyde‐Modified Glycomimetic Ligand Enables Potent and Selective Binding to DC‐SIGN Over L‐SIGN

ChemistryEurope, Volume 4, Issue 5, May 2026.
Mannose derivatives connected to the aminophilic salicylaldehyde tag show high binding affinity for C‐type lectin DC‐SIGN, favored by an imine bond with a protein's Lys residue in the ligand binding site. This reversible‐covalent binding interaction enables ligand selectivity for DC‐SIGN over the closely related L‐SIGN.
Sara Pollastri, Clara Delaunay, Giulia Antonini, Carine Froment, Michel Thépaut, Davide Pasquali, Sarah Mazzotta, Laura Belvisi, Julien Marcoux, Franck Fieschi, Alberto Dal Corso, Anna Bernardi   +11 more
wiley   +1 more source

Fungal Polysaccharides as Next‐Generation Bioactive: Advances in Structure–Activity Mapping, Mode of Action, and Biotechnological Horizons

Food Frontiers, Volume 7, Issue 3, May 2026.
ABSTRACT Fungal polysaccharides (FPs) represent a diverse class of bioactive macromolecules widely studied for their nutritional, therapeutic, and biotechnological value. This review synthesizes recent advances (2020–2025) in the structural characterization, biological functions, and translational potential of FPs.
Muhammad Aaqil, Feng Zhang, Jingchuan Zheng, Muhammad Kamil, Yuwei Guo, Cunchao Zhao, Yang Tian   +6 more
wiley   +1 more source

Controlling sap-sucking insect pests with recombinant endophytes expressing plant lectin [PDF]

, 2010
We developed a novel pest management strategy, which uses endophytes to express anti-pest plant lectins. Fungal endophyte of Chaetomium globosum YY-11 with anti-fungi activities was isolated from rape seedlings, and bacterial endophytes of SJ-10 ...
Gaofu Qi, Nan Lan, Xianfang Zhang, Xinrong Ma, Xiuyun Zhao   +4 more
core   +1 more source

Association Between Polymorphisms rs11003125 and rs7096206 of the MBL2 Gene and the Stages of Hepatitis B Progression in Burkina Faso: A Comparative Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Objectives Hepatitis B virus (HBV) infection remains a major global health burden, with disease progression influenced by host genetic and immune factors, including variants in the mannose‐binding lectin 2 (MBL2) gene. This study aimed to evaluate the association between MBL2 polymorphisms and clinical outcomes of HBV infection ...
Minane Nafissa Triande, Lassina Traore, Sidnooma Véronique Zongo, Teega‐Wendé Clarisse Ouedraogo, Mousso Savadogo, Sanata Nadine Kiemde, Tegwindé Rébéca Compaore, Augustin Tozoula Bambara, Roger Arsène Sombie, Patoinewendé Denise Ilboudo, Albert Théophane Yonli, Bolni Marius Nagalo, Florencia Wendkuuni Djigma, Jacques Simpore   +13 more
wiley   +1 more source

Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy

Journal of Biomedical Materials Research Part A, Volume 114, Issue 5, May 2026.
Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy. Created in BioRender. Jain, E. (2026) https://BioRender.com/x4f9o8g. ABSTRACT Osteoarthritis (OA) is a highly prevalent, disabling, and painful disease of the joints, characterized by progressive cartilage degeneration, synovial fibrosis, and pain.
Era Jain, Paul Nana Kwame Sagoe
wiley   +1 more source

Proteomic and Super‐Resolution Analyses of Murine Brown Adipocyte‐Derived Extracellular Vesicles

Journal of Extracellular Biology, Volume 5, Issue 5, May 2026.
Graphical Abstract ABSTRACT Thermogenic brown adipocytes (BAs) are not only an energy sink but also regulate systemic metabolic health through secreted factors and extracellular vesicles (EVs). Here, we investigate the baseline profiles BA‐EVs and how cold‐induced thermogenesis alters the proteome of BA‐EVs.
Menchus Quan, Yi‐Kai Liu, Maryam Mahmoodi, Muhammad Asif, Madeline Kay, Yongjie Yang, Fang Huang, Weiguo Andy Tao, Shihuan Kuang   +8 more
wiley   +1 more source

Protein glycosylation in lung cancer from a mass spectrometry perspective

Mass Spectrometry Reviews, Volume 45, Issue 3, Page 455-475, May/June 2026.
ABSTRACT Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi, Simon Sugár, Lilla Turiák   +2 more
wiley   +1 more source

A Comparative Study of the Anticancer Potential of Chitin-Binding Lectins From Solanum tuberosum and Solanum annuum

Journal of Food Quality
Lectins are glycan-binding proteins that have been extensively studied for their diverse biological functions, including potential therapeutic applications.
Mst. Sadnima Zaman, Alima Khanam, Md. Rezoan Hossain, Syed Rashel Kabir, A. K. M. Asaduzzaman, Imtiaj Hasan   +5 more
doaj   +1 more source

Glanders: Past, Present and Future of a Neglected Zoonosis as a Threat in Veterinary and Human Health

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This review displays a comprehensive overview of glanders, including aetiology, epidemiology, pathogenesis, diagnosis, control strategies and ongoing eradication programs. It has also reviewed differential diagnosis and treatment both in animals and humans as well as organism's antimicrobial properties.
Yahya Kanani, Ahmad Oryan, Abdollah Derakhshandeh   +2 more
wiley   +1 more source

Beyond the Barrier: Epithelial Cells as Immune Sentinels in the Female Genital Tract

American Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.
ABSTRACT Epithelial cells (ECs) of the female genital tract (FGT) serve as an essential barrier and the first line of defense against sexually transmitted pathogens. Beyond providing a physical barrier, these cells actively contribute to immune responses through pathogen recognition, cytokine release, and modulation of adaptive immune responses ...
Lauren Jirik, Shreya Joshi, Aisha Nazli, Charu Kaushic   +3 more
wiley   +1 more source