Results 1 to 10 of about 68,905 (229)

Distribution of glycan motifs at the surface of midgut cells in the cotton leafworm (Spodoptera littoralis) demonstrated by lectin binding [PDF]

, 2017
Glycans are involved in many biological phenomena, including signal transduction, cell adhesion, immune response or differentiation. Although a few papers have reported on the role of glycans in the development and proper functioning of the insect midgut,
Els J. M. Van Damme, Guy Smagghe, Kaat Cappelle, Kristof De Schutter, Tomasz Walski, Tomasz Walski   +5 more
core   +2 more sources

Biosynthesis and expression of zona pellucida glycoproteins in mammals [PDF]

, 2001
The zona pellucida (ZP) is an extracellular matrix surrounding the oocyte and the early embryo that exerts several important functions during fertilization and early embryonic development.
Kölle, S., Sinowatz, Fred, Töpfer-Petersen, E.   +2 more
core   +1 more source

Altered N-Linked Glycosylation in Follicular Lymphoma and Chronic Lymphocytic Leukemia: Involvement in Pathogenesis and Potential Therapeutic Targeting

Frontiers in Immunology, 2017
B-cell antigen receptor (BCR) expression is indispensable for survival of most B-cell malignancies. In follicular lymphoma (FL), N-linked glycosylation sites are introduced in the immunoglobulin (Ig) variable region genes.
Nurit Hollander, Joseph Haimovich
doaj   +1 more source

The Binding Affinity and Molecular Basis of the Structure-Binding Relationship between Urinary Tamm-Horsfall Glycoprotein and Tumor Necrosis Factor-α

Molecules, 2012
In a previous study we noted significant THP binding to TNF-α, but did not explore the molecular basis of the structure-binding relationship. In this study, we used lectin-binding ELISA to assess the carbohydrate compositions of THP, BSA, IgG, TNF-α, and
Chia-Li Yu, Chang-Youh Tsai, Tsai-Hung Wu, Sue-Cien Siao, Yu-Hsuan Chen, Ko-Jen Li, Cheng-Han Wu   +6 more
doaj   +1 more source

Carbohydrate specificity of sea urchin sperm bindin: a cell surface lectin mediating sperm-egg adhesion. [PDF]

, 1982
We have examined the carbohydrate specificity of bindin, a sperm protein responsible for the adhesion of sea urchin sperm to eggs, by investigating the interaction of a number of polysaccharides and glycoconjugates with isolated bindin.
Glabe, CG, Grabel, LB, Rosen, SD, Vacquier, VD   +3 more
core  

Endoplasmic Reticulum Export of GPI-Anchored Proteins [PDF]

, 2019
Protein export from the endoplasmic reticulum (ER) is an essential process in all eukaryotes driven by the cytosolic coat complex COPII, which forms vesicles at ER exit sites for transport of correctly assembled secretory cargo to the Golgi apparatus ...
López Martín, Sergio, Muñiz Guinea, Manuel, Rodríguez Gallardo, Sofía, Sabido Bozo, Susana   +3 more
core   +1 more source

Mannose Binding Lectin (MBL) and Its Clinical Significance

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2015
BACKGROUND AND OBJECTIVE: Mannose Binding Lectin (MBL) is a key molecule in innate immunity, this acute phase protein, synthesized in the liver, binds to various microorganisms and damaged cells and destroys them by opsonization of aggressive agents and ...
M Asgharzadeh, H Samadi Kafil, M Pourastadi   +2 more
doaj  

Proteomics analysis of serum protein profiling in pancreatic cancer patients by DIGE: up-regulation of mannose-binding lectin 2 and myosin light chain kinase 2

BMC Gastroenterology, 2010
Background Pancreatic cancer has significant morbidity and mortality worldwide. Good prognosis relies on an early diagnosis. The purpose of this study was to develop techniques for identifying cancer biomarkers in the serum of patients with pancreatic ...
Ni Xiaolin, Wu Wenchuan, Hu Jianwen, Hou Chenrui, Jin Dayong, Rong Yefei, Wang Dansong, Lou Wenhui   +7 more
doaj   +1 more source

Crystal Structure of the Cysteine-Rich Domain of Mannose Receptor Complexed with a Sulfated Carbohydrate Ligand [PDF]

, 2000
The macrophage and epithelial cell mannose receptor (MR) binds carbohydrates on foreign and host molecules. Two portions of MR recognize carbohydrates: tandemly arranged C-type lectin domains facilitate carbohydrate-dependent macrophage uptake of ...
Bjorkman, Pamela J., Chirino, Arthur J., Feizi, Ten, Leteux, Christine, Liu, Yang, Misulovin, Ziva, Nussenzweig, Michel C.   +6 more
core   +2 more sources

Impact of bacterial vaginosis, as assessed by nugent criteria and hormonal status on glycosidases and lectin binding in cervicovaginal lavage samples.

PLoS ONE, 2015
The objective of this study was to evaluate the impact of hormonal status and bacterial vaginosis (BV) on the glycosidases present and glycosylation changes as assessed by lectin binding to cervicovaginal lavage constituents. Frozen cervicovaginal lavage
Bernard J Moncla, Catherine A Chappell, Lara K Mahal, Brian M Debo, Leslie A Meyn, Sharon L Hillier   +5 more
doaj   +1 more source