Definitions, 2020 A recombinant protein similar or identical to human mannan-binding lectin (MBL) with opsonin activity. MBL, a soluble pattern recognition receptor (PRR) collectin in the C-type lectin superfamily, is a plasma protein that plays an important role in ...
semanticscholar +2 more sources
Role of Mannose-binding Lectin and Association with Microbial Sensitization in a Cohort of Patients with Atopic Dermatitis [PDF]
Acta Dermato-Venereologica, 2023 Atopic dermatitis is a relapsing inflammatory skin condition, in which bacteria, fungi and viruses may colonize the skin and aggravate the condition. Mannose-binding lectin is part of the innate immune system.
Emma Belfrage +6 more
doaj +2 more sources
The ambiguous role of mannose-binding lectin (MBL) in human immunity. [PDF]
Open Med (Wars), 2021 Mannose-binding lectin (MBL) and lectin complement pathway have become targets of increasing clinical interest. Many aspects of MBL have been recently explored, including the structural properties that allow it to distinguish self from non-self/altered ...
Kalia N, Singh J, Kaur M.
europepmc +2 more sources
Activity of mannose-binding lectin (MBL) in centenarians [PDF]
Aging Cell, 2012 We analyzed MBL2 gene variants in two cohorts of centenarians, octo‐nonagenarians and nonagenarians, and in the general population, one from Sardinia Island (Italy), recruited in the frame of the AKea study, and another from Campania (southern Italy), to
R. Tomaiuolo +12 more
semanticscholar +5 more sources
Influence of the presence of mannose-binding lectin polymorphisms on the occurrence of leishmaniasis: a systematic review and meta-analysis [PDF]
Anais Brasileiros de Dermatologia, 2022 Background Leishmaniasis is caused by an intracellular protozoan of the Leishmania genus. Mannose-binding lectin (MBL) is a serum complement protein and recognizes lipoprotein antigens in protozoa and the bacterial plasma membrane. Nucleotide variants in
Wonei de Seixas Vital +5 more
doaj +2 more sources
Biomolecules, 2020 Lectins have the ability to bind specific carbohydrates and they have potential applications as medical and pharmacological agents. The unique structure and usefulness of red algal lectin have been reported, but these lectins are limited to a few marine ...
Hyun-Ju Hwang +6 more
doaj +2 more sources
Mannose binding lectin is required for alphavirus-induced arthritis/myositis. [PDF]
PLoS Pathogens, 2012 Mosquito-borne alphaviruses such as chikungunya virus and Ross River virus (RRV) are emerging pathogens capable of causing large-scale epidemics of virus-induced arthritis and myositis.
Bronwyn M Gunn +10 more
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Mannose-Binding Lectin and Susceptibility to Schistosomiasis [PDF]
The Journal of Infectious Diseases, 2013 Background. Human ficolin 2 (encoded by FCN2) and mannose-binding lectin (encoded by MBL2) bind to specific pathogen-associated molecular patterns, activate the complement lectin cascade in a similar manner, and are associated with several infectious ...
J. Antony +9 more
semanticscholar +4 more sources
Activity of Mannose-Binding Lectin on Bacterial-Infected Chickens—A Review [PDF]
Animals, 2021 In recent years, diseases caused by pathogenic bacteria have profoundly impacted chicken production by causing economic loss in chicken products and by-product revenues. MBL (mannose-binding lectin) is part of the innate immune system (IIS), which is the
Peter A. Idowu +6 more
doaj +2 more sources
Echinococcus multilocularis Calreticulin Inhibits Lectin Pathway of Complement Activation by Directly Binding to Mannose-Binding Lectin [PDF]
PathogensAlveolar Echinococcosis (AE) is a serious zoonotic disease caused by infection of Echinococcus multilocularis larvae. To survive within the host, E. multilocularis has developed a complex immune evasion mechanism including the inhibition of complement ...
Yuxiao Shao +8 more
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