Results 11 to 20 of about 87,443 (234)

A Novel High-Mannose Specific Lectin from the Green Alga Halimeda renschii Exhibits a Potent Anti-Influenza Virus Activity through High-Affinity Binding to the Viral Hemagglutinin

Marine Drugs, 2017
We have isolated a novel lectin, named HRL40 from the green alga Halimeda renschii. In hemagglutination-inhibition test and oligosaccharide-binding experiment with 29 pyridylaminated oligosaccharides, HRL40 exhibited a strict binding specificity for high-
Jinmin Mu, Makoto Hirayama, Yuichiro Sato, Kinjiro Morimoto, Kanji Hori   +4 more
doaj   +2 more sources

Mannose-binding lectin deficiency and acute exacerbations of chronic obstructive pulmonary disease

International Journal of COPD, 2012
Richard K Albert,1 John Connett,2 Jeffrey L Curtis,3,4 Fernando J Martinez,3 MeiLan K Han,3 Stephen C Lazarus,5 Prescott G Woodruff51Medicine Service, Denver Health and Department of Medicine, University of Colorado Denver, Denver, CO, 2Division of ...
Woodruff PG, Lazarus SC, Han MK, Martinez FJ, Curtis JL, Connett J, Albert RK   +6 more
doaj   +2 more sources

Mannose-binding lectin deficiency

Radiopaedia.org, 2014
Mannose-binding lectin plays an important role in the body's immune response by attaching to foreign invaders such as bacteria, viruses, or yeast and turning on (activating) the complement system.
Daniel Bell, Y. Weerakkody
semanticscholar   +2 more sources

Steroid‐Refractory Cryptogenic Organising Pneumonia (COP) in a Patient With Mannose‐Binding Lectin (MBL) Deficiency [PDF]

Respirology Case Reports
We report a 67‐year‐old man with a relapse characterised by fever, respiratory failure and bilateral infiltrates following completion of a short‐term empirical methylprednisolone regimen for a similar episode.
Ilias E. Dimeas, Sotirios I. Sinis, Paraskevi Kirgou, Cormac McCarthy, Zoe Daniil   +4 more
doaj   +2 more sources

Mannose binding lectin defects and autoimmune diseases [PDF]

Records of Pharmaceutical & Biomedical Sciences, 2022
Complement system has a very important role in our defense against different pathogens and harmful immune complexes. The lectin pathway of complement system is activated by mannose binding lectin leading to complement cascade ending with the removal of ...
Marwa Azab, Hany Hashem, Emad Eldin Ibrahim, Hoda Abdallah, Ali Abdelrahman, Mohammed Behairy   +5 more
doaj   +1 more source

Mannose-binding lectin and complement mediate follicular localization and enhanced immunogenicity of diverse protein nanoparticle immunogens

Cell Reports, 2022
SUMMARY Nanoparticle (NP) vaccine formulations promote immune responses through multiple mechanisms. We recently reported that mannose-binding lectin (MBL) triggers trafficking of glycosylated HIV Env-immunogen NPs to lymph node follicles.
Benjamin J. Read, Lori Won, J. C. Kraft, Isaac Sappington, Aereas Aung, Shengwei Wu, Julia Bals, Chengbo Chen, Kelly K. Lee, D. Lingwood, N. King, D. Irvine   +11 more
semanticscholar   +1 more source

Characterization of a mannose-binding lectin from channel catfish (Ictalurus punctatus)

Research in Veterinary Science, 2012
Liqiao Chen, Eric Peatman, Zhanjiang Liu   +2 more
exaly   +2 more sources

The ‘involution’ of mannose-binding lectin [PDF]

Human Molecular Genetics, 2005
Mannose-binding lectin (MBL) acts as a serum opsonin in innate immune defense and induces complement activation by the lectin pathway. In humans, low levels of functional serum MBL are caused by the dominant action of three single nucleotide substitutions in exon 1 that disrupt the glycine-rich backbone structure of the protein.
Jeanette, Seyfarth, Peter, Garred, Hans O, Madsen   +2 more
openaire   +2 more sources

Man-Specific Lectins from Plants, Fungi, Algae and Cyanobacteria, as Potential Blockers for SARS-CoV, MERS-CoV and SARS-CoV-2 (COVID-19) Coronaviruses: Biomedical Perspectives

Cells, 2021
Betacoronaviruses, responsible for the “Severe Acute Respiratory Syndrome” (SARS) and the “Middle East Respiratory Syndrome” (MERS), use the spikes protruding from the virion envelope to attach and subsequently infect the host cells.
Annick Barre, Els J. M. Van Damme, Mathias Simplicien, Sophie Le Poder, Bernard Klonjkowski, Hervé Benoist, David Peyrade, Pierre Rougé   +7 more
doaj   +1 more source

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

Hepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog, Reika Fujiwara, Stephanie Q. Pan, Khairat B. El‐Baradie, Hye Yeon Choi, Sonal Sinha, Qihong Yang, Kinji Asahina, Yibu Chen, Meng Li, Matthew Salomon, Stanley W.‐K. Ng, Hidekazu Tsukamoto   +12 more
wiley   +1 more source