Results 11 to 20 of about 43,575 (199)
The ‘involution’ of mannose-binding lectin [PDF]
Human Molecular Genetics, 2005 Mannose-binding lectin (MBL) acts as a serum opsonin in innate immune defense and induces complement activation by the lectin pathway. In humans, low levels of functional serum MBL are caused by the dominant action of three single nucleotide substitutions in exon 1 that disrupt the glycine-rich backbone structure of the protein.
Jeanette, Seyfarth +2 more
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Activity of mannose‐binding lectin in centenarians [PDF]
Aging Cell, 2012 SummaryWe analyzed MBL2 gene variants in two cohorts of centenarians, octo‐nonagenarians and nonagenarians, and in the general population, one from Sardinia Island (Italy), recruited in the frame of the AKea study, and another from Campania (southern Italy), to search for haplotypes related to longevity.
TOMAIUOLO, R +12 more
openaire +4 more sources
Mannose-Binding Lectin in HIV Infection [PDF]
Future Virology, 2008 Infection with HIV represents a significant global health problem, with high infection rates and high mortality worldwide. Treatment with antiretroviral therapy is inaccessible to many patients and efficacy is limited by development of resistance and side effects.
Sarah, Eisen +2 more
openaire +2 more sources
Mannose‐binding lectin and gastric cancer [PDF]
International Journal of Cancer, 2007 Daniel L. Worthley*, Peter G. Bardy, David L. Gordon and Charles G. Mullighan Department of Gastroenterology and Hepatology, Flinders Medical Centre, South Australia, Australia Division of Hematology, Royal Adelaide Hospital and Institute of Medical and Veterinary Science, South Australia, Australia Department of Hematology–Oncology, The Queen ...
Worthley, D. +3 more
openaire +3 more sources
Haematologica, 2010 Background Life-threatening infections are a major cause of death after allogeneic stem cell transplantation. Complement Mannose-binding lectin is a key component of innate immunity.
Michael Osthoff +6 more
doaj +1 more source
COVID-19 Recurrence Without Seroconversion in a Patient With Mannose-Binding Lectin Deficiency
Allergy & Rhinology, 2021 Introduction The SARS-CoV-2 virus has infected more than 63,000,000 people worldwide after emerging from Wuhan, China in December 2019. This outbreak was declared a Public Health Emergency in January 2020, and a pandemic in March. While rare, reinfection
Breanne Hayes DO +2 more
doaj +1 more source
Cell-surface protein YwfG of Lactococcus lactis binds to α-1,2-linked mannose
PLoS ONE, 2023 Lactococcus lactis strains are used as starter cultures in the production of fermented dairy and vegetable foods, but the species also occurs in other niches such as plant material. Lactococcus lactis subsp. lactis G50 (G50) is a plant-derived strain and
Wataru Tsuchiya +7 more
doaj +2 more sources
Mannose binding lectin is required for alphavirus-induced arthritis/myositis. [PDF]
PLoS Pathogens, 2012 Mosquito-borne alphaviruses such as chikungunya virus and Ross River virus (RRV) are emerging pathogens capable of causing large-scale epidemics of virus-induced arthritis and myositis.
Bronwyn M Gunn +10 more
doaj +1 more source
Mannose-Binding Lectin and Susceptibility to Schistosomiasis [PDF]
The Journal of Infectious Diseases, 2013 Human ficolin 2 (encoded by FCN2) and mannose-binding lectin (encoded by MBL2) bind to specific pathogen-associated molecular patterns, activate the complement lectin cascade in a similar manner, and are associated with several infectious diseases. Our recently published study established certain FCN2 promoter variants and ficolin-2 serum levels as ...
Justin S, Antony +9 more
openaire +3 more sources
Revista da Sociedade Brasileira de Medicina Tropical, 2015 INTRODUCTION : We hypothesized higher mannose-binding lectin level and classic factors (i.e., age, sex, alcohol consumption, exposure, and specific treatment) are associated with the severity of periportal fibrosis in schistosomiasis.
Paula Carolina Valença Silva +5 more
doaj +1 more source