Role of Mannose-binding Lectin and Association with Microbial Sensitization in a Cohort of Patients with Atopic Dermatitis. [PDF]
Atopic dermatitis is a relapsing inflammatory skin condition, in which bacteria, fungi and viruses may colonize the skin and aggravate the condition. Mannose-binding lectin is part of the innate immune system.
Belfrage E +6 more
europepmc +2 more sources
Mannose-binding lectin deficiency with eosinophilic meningoencephalitis due to
Introduction Eosinophilic meningitis, a potentially fatal disease caused by Angiostrongylus cantonensis, is considered an emerging infectious disease.
de Paula-Almeida Olga +6 more
doaj +3 more sources
Lectin-like bacteriocins from Pseudomonas spp. utilise D-rhamnose containing lipopolysaccharide as a cellular receptor. [PDF]
Lectin-like bacteriocins consist of tandem monocot mannose-binding domains and display a genus-specific killing activity. Here we show that pyocin L1, a novel member of this family from Pseudomonas aeruginosa, targets susceptible strains of this species ...
Laura C McCaughey +12 more
doaj +9 more sources
Influence of the presence of mannose-binding lectin polymorphisms on the occurrence of leishmaniasis: a systematic review and meta-analysis. [PDF]
Background Leishmaniasis is caused by an intracellular protozoan of the Leishmania genus. Mannose-binding lectin (MBL) is a serum complement protein and recognizes lipoprotein antigens in protozoa and the bacterial plasma membrane. Nucleotide variants in
Vital WS +5 more
europepmc +3 more sources
What contributes to an effective mannose recognition domain? [PDF]
In general, carbohydrate–lectin interactions are characterized by high specificity but also low affinity. The main reason for the low affinities are desolvation costs, due to the numerous hydroxy groups present on the ligand, together with the typically ...
Christoph P. Sager +4 more
doaj +4 more sources
Activity of Mannose-Binding Lectin on Bacterial-Infected Chickens-A Review. [PDF]
In recent years, diseases caused by pathogenic bacteria have profoundly impacted chicken production by causing economic loss in chicken products and by-product revenues. MBL (mannose-binding lectin) is part of the innate immune system (IIS), which is the
Idowu PA +6 more
europepmc +2 more sources
<i>Echinococcus multilocularis</i> Calreticulin Inhibits Lectin Pathway of Complement Activation by Directly Binding to Mannose-Binding Lectin. [PDF]
Alveolar Echinococcosis (AE) is a serious zoonotic disease caused by infection of Echinococcus multilocularis larvae. To survive within the host, E. multilocularis has developed a complex immune evasion mechanism including the inhibition of complement ...
Shao Y +8 more
europepmc +2 more sources
Steroid-Refractory Cryptogenic Organising Pneumonia (COP) in a Patient With Mannose-Binding Lectin (MBL) Deficiency. [PDF]
We report a 67‐year‐old man with a relapse characterised by fever, respiratory failure and bilateral infiltrates following completion of a short‐term empirical methylprednisolone regimen for a similar episode.
Dimeas IE +4 more
europepmc +2 more sources
Mannose-binding lectin may affect pregnancy outcome
Mannose-binding lectin (MBL) is a component of the innate immune system and acts as a complement activator through the lectin pathway. Genetic variations of MBL and low MBL levels cause several infection problems, which may also be related to ...
Şebnem Çalkavur +9 more
doaj +3 more sources
Betacoronaviruses, responsible for the “Severe Acute Respiratory Syndrome” (SARS) and the “Middle East Respiratory Syndrome” (MERS), use the spikes protruding from the virion envelope to attach and subsequently infect the host cells.
Annick Barre +7 more
doaj +1 more source

