Results 11 to 20 of about 15,589 (264)

Man-Specific, GalNAc/T/Tn-Specific and Neu5Ac-Specific Seaweed Lectins as Glycan Probes for the SARS-CoV-2 (COVID-19) Coronavirus

Marine Drugs, 2020
Seaweed lectins, especially high-mannose-specific lectins from red algae, have been identified as potential antiviral agents that are capable of blocking the replication of various enveloped viruses like influenza virus, herpes virus, and HIV-1 in vitro.
Annick Barre, Els J.M. Van Damme, Mathias Simplicien, Hervé Benoist, Pierre Rougé   +4 more
doaj   +1 more source

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

Hepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog, Reika Fujiwara, Stephanie Q. Pan, Khairat B. El‐Baradie, Hye Yeon Choi, Sonal Sinha, Qihong Yang, Kinji Asahina, Yibu Chen, Meng Li, Matthew Salomon, Stanley W.‐K. Ng, Hidekazu Tsukamoto   +12 more
wiley   +1 more source

Novel Urinary Glycan Biomarkers Predict Cardiovascular Events in Patients With Type 2 Diabetes: A Multicenter Prospective Study With 5-Year Follow Up (U-CARE Study 2)

Frontiers in Cardiovascular Medicine, 2021
Background: Although various biomarkers predict cardiovascular event (CVE) in patients with diabetes, the relationship of urinary glycan profile with CVE in patients with diabetes remains unclear.Methods: Among 680 patients with type 2 diabetes, we ...
Koki Mise, Mariko Imamura, Satoshi Yamaguchi, Mayu Watanabe, Chigusa Higuchi, Akihiro Katayama, Satoshi Miyamoto, Haruhito A. Uchida, Atsuko Nakatsuka, Jun Eguchi, Kazuyuki Hida, Tatsuaki Nakato, Atsuhito Tone, Sanae Teshigawara, Takashi Matsuoka, Shinji Kamei, Kazutoshi Murakami, Ikki Shimizu, Katsuhiro Miyashita, Shinichiro Ando, Tomokazu Nunoue, Michihiro Yoshida, Masao Yamada, Kenichi Shikata, Jun Wada   +24 more
doaj   +1 more source

Mannose‐binding lectin and gastric cancer [PDF]

International Journal of Cancer, 2007
Daniel L. Worthley*, Peter G. Bardy, David L. Gordon and Charles G. Mullighan Department of Gastroenterology and Hepatology, Flinders Medical Centre, South Australia, Australia Division of Hematology, Royal Adelaide Hospital and Institute of Medical and Veterinary Science, South Australia, Australia Department of Hematology–Oncology, The Queen ...
Worthley, D., Bardy, P., Gordon, D., Mullighan, C.   +3 more
openaire   +3 more sources

The carbohydrate-binding specificity and molecular modelling of Canavalia maritima and Dioclea grandiflora lectins

Memorias do Instituto Oswaldo Cruz, 1996
The carbohydrate-binding specificity of lectins from the seeds of Canavalia maritima and Dioclea grandiflora was studied by hapten-inhibition of haemagglutination using various sugars and sugar derivatives as inhibitors, including N-acetylneuraminic acid
Márcio Viana Ramos, Renato de Azevedo Moreira, José Tadeu Abreu Oliveira, Benildo Sousa Cavada, Pierre Rougé   +4 more
doaj   +1 more source

The ‘involution’ of mannose-binding lectin [PDF]

Human Molecular Genetics, 2005
Mannose-binding lectin (MBL) acts as a serum opsonin in innate immune defense and induces complement activation by the lectin pathway. In humans, low levels of functional serum MBL are caused by the dominant action of three single nucleotide substitutions in exon 1 that disrupt the glycine-rich backbone structure of the protein.
Jeanette, Seyfarth, Peter, Garred, Hans O, Madsen   +2 more
openaire   +2 more sources

Effect of Leguminous Lectins on the Growth of Rhizobium tropici CIAT899

Molecules, 2013
Rhizobium tropici is a Gram-negative bacterium that induces nodules and fixed atmospheric nitrogen in symbiotic association with Phaseolus vulgaris (common bean) and some other leguminous species.
Mayron Alves de Vasconcelos, Cláudio Oliveira Cunha, Francisco Vassiliepe Sousa Arruda, Victor Alves Carneiro, Rafaela Mesquita Bastos, Fábio Martins Mercante, Kyria Santiago do Nascimento, Benildo Sousa Cavada, Ricardo Pires dos Santos, Edson Holanda Teixeira   +9 more
doaj   +1 more source

Interaction of Diocleinae Lectins with Glycoproteins Based in Surface Plasmon Resonance

Memorias do Instituto Oswaldo Cruz, 2002
Interaction of glucose/mannose-binding lectins in solution with immobilized glycoproteins was followed in real time using surface plasmon resonance technology.
Marcio V Ramos, Benildo S Cavada, Anne-Marie Mazard, Pierre Rougé   +3 more
doaj   +1 more source

Mannose-Specific Lectins from Marine Algae: Diverse Structural Scaffolds Associated to Common Virucidal and Anti-Cancer Properties

Marine Drugs, 2019
To date, a number of mannose-specific lectins have been isolated and characterized from seaweeds, especially from red algae. In fact, man-specific seaweed lectins consist of different structural scaffolds harboring a single or a few carbohydrate-binding ...
Annick Barre, Mathias Simplicien, Hervé Benoist, Els J.M. Van Damme, Pierre Rougé   +4 more
doaj   +1 more source

Isolation and partial characterisation of a novel lectin from Aegle marmelos fruit and its effect on adherence and invasion of Shigellae to HT29 cells. [PDF]

PLoS ONE, 2011
Lectins are a class of ubiquitous proteins/glycoproteins that are abundantly found in nature. Lectins have unique carbohydrate binding property and hence have been exploited as drugs against various infectious diseases.
Subramaniya Bharathi Raja, Malliga Raman Murali, Nirmal Kasinathan Kumar, Sivasitambaram Niranjali Devaraj   +3 more
doaj   +1 more source