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Mannose‐binding lectin and vulvovaginal candidiasis

International Journal of Gynecology & Obstetrics, 2005
AbstractObjective: To investigate the effect of mannose‐binding lectin (MBL) gene polymorphism on the immune system and the significance of vaginal MBL concentration in the pathogenesis of vulvovaginal candidiasis (VVC) and recurrent VVC (rVVC). Patients and methods: Mannose‐binding lectin concentrations in CVL samples from 111 women were collected ...
Zhaohui Liu, Fei Liu, Qinping Liao
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Mannose‐binding lectin levels in children with asthma

Pediatric Allergy and Immunology, 2005
Mannose‐binding lectin (mbl), one of the important components of innate immunity, can activate the lectin pathway of the complement system. After binding mannose containing carbohydrate structures of foreign antigen, mbl initiates and regulates the inflammatory responses. Asthma is a complex inflammatory disease of the lung involving many components of
S. Halide Akbas   +4 more
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Mannose binding lectin gene polymorphisms and asthma

Clinical & Experimental Allergy, 2007
SummaryBackground Bronchial asthma is a chronic inflammatory disorder of the airways. Recently, it has been suggested that complement plays significant roles in asthma. Mannose‐binding lectin (MBL) is one of the key molecules in complement activation pathways that are associated with several infectious and immune disorders.Subjects and method
Xintao Wang   +5 more
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Mannose-Binding Lectins in Cerebrum Development

2003
The nervous system is so complex that it is not ordinarily considered as an interesting model for studying cellular mechanisms. However, its morphology (at least in some well-defined areas) provides essential information because cells are polarised: cell body, axons and dendrites can be easily identified in vivo, an essential property when studies are ...
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Anti-microbial activities of mannose-binding lectin

Biochemical Society Transactions, 2003
Mannose-binding lectin (MBL; also known as mannan-binding lectin) is involved in first-line defence by binding to bacteria, viruses, protozoa and helminths through a pattern-recognition mode of detection and then initiating a range of host responses. Currently, we have been unable to extrapolate from what we know of the biochemistry of MBL binding to ...
Malcolm W. Turner, D.L. Jack
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Mannose-binding lectin genetics: from A to Z

Biochemical Society Transactions, 2008
MBL (mannose-binding lectin) is primarily a liver-derived collagen-like serum protein. It binds sugar structures on micro-organisms and on dying host cells and is one of the four known mediators that initiate activation of the complement system via the lectin pathway.
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Ureaplasma urealyticum binds mannose-binding lectin

Experimental and Molecular Pathology, 2004
Mannose-binding C-type lectin (MBL) is an important component of innate immunity in mammals. Mannose-binding lectin (MBL), an acute phase protein, acts as an opsonin for phagocytosis and also activates the mannan-binding lectin complement pathway. It may play a particularly significant role during infancy before adequate specific protection can be ...
Dennis T Crouse   +3 more
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Mannose‐binding lectin gene polymorphisms in relation to periodontitis

Journal of Clinical Periodontology, 2008
AbstractAim: To investigate the correlation of six functional polymorphisms in the MBL gene with MBL plasma levels in relation to periodontitis.Material and Methods: A total of 92 periodontitis patients and 70 controls, all of Caucasian origin, were included.
Louropoulou, A.   +5 more
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The role of mannose-binding lectin in health and disease

Molecular Immunology, 2003
Mannose-binding lectin (MBL) is a pattern recognition molecule of the innate immune system. It belongs to the collectin family of proteins in which lectin (carbohydrate-recognition) domains are found in association with collagenous structures. In man, these proteins include serum MBL, lung surfactant protein A (SP-A) and lung surfactant protein D (SP-D)
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