Development and Application of a Functional Human Esophageal Mucosa Explant Platform to Eosinophilic Esophagitis. [PDF]
There is an increasing prevalence of esophageal diseases but intact human tissue platforms to study esophageal function, disease mechanisms, and the interactions between cell types in situ are lacking.
Aceves, Seema S +12 more
core +3 more sources
Anorectal Manometry in Pediatric Colorectal Surgical Care
Background: Pediatric colorectal specialists care for patients with a variety of defecation disorders. Anorectal (AR) manometry testing is a valuable tool in the diagnosis and management of these children.
Justin C. Wheeler +2 more
doaj +1 more source
Laryngopharyngeal reflux diagnostics: review article
Laryngopharyngeal reflux (LPR) is an actual, modern problem for the practice of an ENT doctor, because majority of complaints lead the patient, first of all, to an otorhinolaryngologist.
I. B. Angotoeva +4 more
doaj +1 more source
Stuck in the Middle! A Case of Repeated Foreign Body Impaction in Oesophagus [PDF]
Oesophageal foreign body impaction is usually seen in children as well as in adults with varying aetiologies. It is an emergency situation requiring proper evaluation and prompt treatment because of the possible complications like oesophageal ...
P Kiranmayi, Y Radha Krishna
doaj +1 more source
Quantitative assessment of multichannel intraluminal impedance pH and its clinical implications
We sought to quantify the characteristics of acid reflux episodes in patients with extraesophageal GERD symptoms (EES), hiatal hernia (HH), and erosive esophagitis (EroE) using multichannel intraluminal impedance pH (MII‐pH) and investigate the ...
Eden Koo +4 more
doaj +1 more source
This review introduces the updated Chicago Classification ver. 4.0 for esophageal motility disorders using metrics from high-resolution manometry (HRM). The Chicago Classification ver. 4.0 was developed by 52 diverse international experts using validated
Tae Hee Lee
doaj +1 more source
Aging-associated changes in microRNA expression profile of internal anal sphincter smooth muscle: Role of microRNA-133a. [PDF]
A comprehensive genomic and proteomic, computational, and physiological approach was employed to examine the (previously unexplored) role of microRNAs (miRNAs) as regulators of internal anal sphincter (IAS) smooth muscle contractile phenotype and basal ...
Addya, Sankar +6 more
core +3 more sources
Effects of Laryngeal Restriction on Pharyngeal Peristalsis and Biomechanics: Clinical Implications [PDF]
To date, rehabilitative exercises aimed at strengthening the pharyngeal muscles have not been developed due to the inability to successfully overload and fatigue these muscles during their contraction, a necessary requirement for strength training.
Balasubramanian, Gokulakrishnan +5 more
core +2 more sources
Rapid and Accurate Pressure Sensing Device for Direct Measurement of Intraocular Pressure. [PDF]
PurposeIntraocular pressure (IOP) is the primary modifiable risk factor for glaucoma. Current devices measure IOP via the dynamic response of the healthy cornea and do not provide the accurate IOP measurements for patients with altered corneal ...
Camp, Andrew +4 more
core
Case‐Based Immunology: B Cells and Systemic Sclerosis Interstitial Lung Disease
Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc), with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to US Food and Drug Administration–approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of ILDs of other systemic autoimmune
Nina Goldman +2 more
wiley +1 more source

