During filarial nematode infection with Litomosoides sigmodontis, PD‐L2 down‐regulates Th2 cell expression of GATA‐3 and Th2 cytokines and enables parasite survival. Concurrently, B cells suppress protective immunity through a mechanism that does not involve PD‐L2.
Johanna A. Knipper +3 more
wiley +1 more source
Molecular Epidemiology of Mansonella Species in Gabon [PDF]
Abstract Mansonella perstans, a filarial nematode, infects large populations in Africa and Latin America. Recently, a potential new species, Mansonella sp “DEUX,” was reported. Carriage of endosymbiotic Wolbachia opens treatment options for Mansonella infections.
Thaisa Lucas Sandri +13 more
openaire +2 more sources
Neglected Tropical Diseases and Female Infertility: Possible Pathophysiological Mechanisms
Battling female infertility has posed a global challenge, where neglected tropical diseases (NTDs) are nonetheless a notable contributing factor. NTDs affect a variety of diseases, often of a chronic nature, which are often cited as some of the most lethal diseases operating against the most economically disadvantaged populations across the globe.
Moses Agbomhere Hamed +8 more
wiley +1 more source
En face view ofMansonella (Mansonella) akitensis(Uni, 1983) by scanning electron microscopy [PDF]
The en face view of the head of M. (M.) akitensis was examined by scanning electron microscopy (SEM). The cephalic extremity with major axis dorsoventral confirmed the taxonomical position of the species.
openaire +2 more sources
Detection of Filariid Infections in Mexican Primate Populations Through qPCR
Using a combination of noninvasive sampling and molecular diagnostic techniques, we detected filariae infections in wild spider monkeys and black howler monkeys across southern Mexico by screen for filariid DNA in host feces through qPCR protocols, with an overall prevalence of 26% positive cases.
Brenda Solórzano‐García +3 more
wiley +1 more source
Complete Mitochondrial Genome Sequence of Mansonella perstans
The 13,647-bp complete mitochondrial genome of Mansonella perstans was sequenced and is syntenic to the mitochondrial genome of Mansonella ozzardi . Phylogenetic analysis of the mitochondrial genome is consistent with the known phylogeny of ONC5 group filarial nematodes.
Matthew Chung +14 more
openaire +2 more sources
Our research explores to use and optimization of molecular methods for the detection and identification of DNA from filarial nematodes in Galapagos sea lion whole blood samples. We developed an accessible workflow for the genus and species‐level identifications of filarial nematodes present in wildlife DNA samples, and used this assay to test 28 ...
Isabella G. Livingston +10 more
wiley +1 more source
Associations Between Helminth Infections, Plasmodium falciparum Parasite Carriage and Antibody Responses to Sexual and Asexual Stage Malarial Antigens. [PDF]
Infections with helminths and Plasmodium spp. overlap in their geographical distribution. It has been postulated that helminth infections may influence malarial transmission by altering Plasmodium falciparum gametocytogenesis.
Adegnika, Ayola Akim +9 more
core +9 more sources
The effect of anthelmintic treatment during pregnancy on HIV plasma viral load: results from a randomized, double-blind, placebo-controlled trial in Uganda. [PDF]
BACKGROUND: To investigate the effect of helminth infections and their treatment during pregnancy on HIV load, we conducted a 2 × 2 factorial randomized controlled trial of albendazole versus placebo and praziquantel versus placebo in pregnant women in ...
Elliott, Alison M +8 more
core +1 more source
Another tool in the toolbox: Aphid‐specific Wolbachia protect against fungal pathogens
Wolbachia infected more than 80% of Pentalonia aphids sampled across the Hawaiian Islands and other locations. The aphid‐specific M‐supergroup strains of this symbiont protected against a specialist fungal pathogen, Pandora, but not the generalist pathogen Beauveria or the parasitoid Aphidius colemanii.
Clesson H. V. Higashi +6 more
wiley +1 more source

