Results 1 to 10 of about 14,403 (89)

Genetic Testing Unveils a Novel Thrombospondin‐1 Domain Containing Protein 1 Gene Variant as the Cause of Chronic Edema in a 79‐Year‐Old Woman

Clinical Genetics, EarlyView.
A 79‐year‐old woman with lifelong peripheral edema and an affected sister was found to harbor a novel homozygous THSD1 splice‐site variant. Reduced THSD1 expression in dermal endothelial cells supported the possibility that this variant contributes to chronic hereditary edema.
Eiko Amo, Takafumi Toyohara, Naoya Saijo, Satoko Sato, Jun Takayama, Yoshiko Suto, Yuji Noguchi, Sosuke Kinomura, Yusuke Ishizuka, Shun Watanabe, Koichi Kikuchi, Rui Makino, Mai Yoshida, Yuji Oe, Tasuku Nagasawa, Koji Okamoto, Takehiro Suzuki, Mariko Miyazaki, Shinya Kawaguchi, Takashi Suzuki, Takaaki Abe, Shigeo Kure, Atsuo Kikuchi, Tetsuhiro Tanaka   +23 more
wiley   +1 more source

The Role of Innate Lymphoid Cells in Autoimmune, Allergic and Infectious Diseases: A Systematic Review

Immunology, EarlyView.
This systematic review establishes disease‐specific dysregulations of human innate lymphoid cells (ILCs), demonstrating that an ILC1/ILC3 imbalance compromises mucosal barriers in inflammatory bowel disease, while activated ILC2s drive allergic airway inflammation.
Luan F. Lückmann, Henrique R. Dal‐Pizzol, Louise M. Lückmann, Davi E. Salini, Bruna C. Hasckel, Mikaeli Minati, Bruno Kluwe‐Schiavon, Tatiana Barichello   +7 more
wiley   +1 more source

Addressing Behavioural Determinants of Cutaneous Leishmaniasis Through Community Dialogue in Kalu District, Ethiopia: A Mixed‐Methods Study

Tropical Medicine &International Health, EarlyView.
ABSTRACT Background Cutaneous leishmaniasis (CL) is a major public health challenge in Ethiopia, with 20–30,000 new cases annually. Limited awareness and misconceptions contribute to delayed care seeking, stigma, prolonged healing, and reduced uptake of preventive measures in CL‐endemic communities.
Takele Gezahegn Demie, Tara Mtuy, Jennifer Palmer, Eshetu Girma, Yohannes Hailemichael, Teklu Cherkose, Telahun Kasa Tefera, Mohammedjud Hassen Ahmed, Catherine Pitt, Michael Marks, Stephen L. Walker, Endalamaw Gadisa, Mirgissa Kaba, SHARP collaboration   +13 more
wiley   +1 more source

Differential Effect of Ivermectin on Intestinal Helminths in Multimmate Mouse (Mastomys natalensis)

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Mastomys natalensis harbours gastrointestinal helminths of public health and food‐safety importance. This study identified five helminth taxa and assessed faecal egg counts after a single ivermectin dose. Egg counts declined substantially in treated rodents but changed little in controls over eight weeks.
Claus Thomas, Venance Msoffe, Gilbert Mwamengele, Stella Kessy, Emmanuel Hape, Godfrey Katusi, Christopher Sabuni, Isaac Makundi, Herwig Leirs, Robert Machang'u   +9 more
wiley   +1 more source

Eosinophilia in the Tropics: Should Empirical Anthelmintic Treatment Be Considered Standard Practice? A Prospective Cohort Study

Tropical Medicine &International Health, Volume 31, Issue 10, Page 1433-1442, October 2026.
ABSTRACT Background Eosinophilia is a common clinical finding with diverse etiologies. Helminthiasis is a major aetiology in tropical regions, but data from haematology consultation services at tertiary centres in endemic settings are limited. Objectives To determine the prevalence of helminthiasis among patients with eosinophilia at a tropical ...
Smith Kungwankiattichai, Patsharaporn T. Sarasombath, Pattaraporn Tunsing, Weerapat Owattanapanich   +3 more
wiley   +1 more source

Host, vector, and parasite dynamics: exploring intrinsic and extrinsic factors shaping tick‐borne filarial nematode transmission

Biological Reviews, Volume 101, Issue 4, Page 1779-1792, August 2026.
ABSTRACT Tick‐borne filarial nematodes are a complex and understudied group of parasites that rely on ticks for transmission in vertebrates. This review examines how intrinsic and extrinsic factors may influence the successful transmission of filarial nematodes in tick vectors, drawing insights from extensively studied haematophagous dipteran vector ...
Oluwaseun D. Ajileye, Gabriel L. Hamer, Sarah A. Hamer, Guilherme G. Verocai, Jessica E. Light   +4 more
wiley   +1 more source

Diversity and Distribution Patterns of Insects in Nigeria: A GBIF‐Based Appraisal

Ecology and Evolution, Volume 16, Issue 8, August 2026.
Insect diversity in Nigeria is high, with 5880 species. Diversity differs between biomes. Current diversity represents ~21 of the estimated ‘true’ diversity. ABSTRACT Insects provide essential ecosystem services and are key indicators of ecosystem health.
Emelie Obi, Mikaelison da Silva Lima, Kelechi Amadi, Maduamaka C. Abajue   +3 more
wiley   +1 more source

Mechanistic‐Statistical Inference of Mosquito Dynamics From Mark‐Release‐Recapture Data

Population Ecology, Volume 68, Issue 3, July 2026.
Mark‐release‐recapture data contain valuable information on mosquito dispersal and survival, but this information is only indirectly observed through trap counts. We combine a mechanistic diffusion model with a statistical observation model to infer movement, mortality, and trap efficiency jointly.
Nga Nguyen, Olivier Bonnefon, René Gato, Luis Almeida, Lionel Roques   +4 more
wiley   +1 more source

Pink Polypoid Papulo‐Vesicles on Labia Majora

JEADV Clinical Practice, EarlyView.
Maria Chiara Mercuri, Michela Tabanelli, Silvia Zago, Diego Abbenante   +3 more
wiley   +1 more source

Safety and immunogenicity of an adjuvanted human onchocerciasis vaccine candidate, OvMANE1: preclinical evaluation in a mice model

Clinical &Translational Immunology, Volume 15, Issue 7, 2026.
OvMANE1 formulated with Freund's adjuvant was safe and elicited strong humoral and cellular immune responses, including significant IgG and leukocyte activation. These findings highlight OvMANE1 as a promising multi‐epitope vaccine candidate for advancing onchocerciasis prevention.
Derrick Neba Nebangwa, Mary Teke Efeti, Sonia M. E. Momnougui, Cabirou Mounchili Shintouo, Robert Adamu Shey, Rene Bilingwe Ayiseh, Fidele Ntie‐Kang, Stephen Mbigha Ghogomu   +7 more
wiley   +1 more source