Results 101 to 110 of about 88,229 (302)

Detección del DIF en ítems politómicos mediante el uso de los métodos Mantel-Haenszel [PDF]

, 2010
Los métodos Mantel-Haenszel (MH) constituyen uno de los procedimientos de referencia usados para la detección del funcionamiento diferencial de los ítems (DIF), tanto en ítems dicotómicos como politómicos.
Aguerri, María Ester, Fernández Alonso, Rubén, Fidalgo Aliste, Ángel Manuel, Pons Piulats, Francisco, Quintanilla Cobián, Laura   +4 more
core  

Efficacy and safety of CT‐868, a novel, fully biased, dual glucagon‐like peptide‐1/glucose‐dependent insulinotropic polypeptide receptor agonist, in type 2 diabetes: A double‐blind, randomized placebo controlled phase 2 trial

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims To assess the glycaemic efficacy and safety of CT‐868, a cAMP signal‐biased, dual glucagon‐like peptide‐1/glucose‐dependent insulinotropic polypeptide receptor agonist, in participants with type 2 diabetes (T2D). Materials and Methods This 26‐week (W), phase 2, randomized, double‐blind placebo‐controlled trial enrolled adults with T2D ...
Manu V. Chakravarthy, Michael A. Elliott, Luis Acosta, Gabriele E. Sonnenberg, Damian Bialonczyk, Jingtao Wu, Federico A. Argüelles‐Tello, Raymundo Garcia‐Reza, José Gerardo González‐González, Stig K. Hansen, Juan P. Frias   +10 more
wiley   +1 more source

Efficacy and safety of combining empagliflozin in people with type 2 diabetes mellitus uncontrolled with metformin and sitagliptin: A randomised, double‐blind, multicentre, therapeutic confirmatory phase 3 clinical trial

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aim This study evaluated the efficacy and safety of empagliflozin 10 and 25 mg compared to placebo as add‐on treatment for people with type 2 diabetes mellitus (T2DM) uncontrolled after ≥8 weeks of treatment with metformin and sitagliptin. Materials and Methods A randomised, double‐blind, multicentre, therapeutic confirmatory, phase 3 clinical
Seung‐Hwan Lee, Kyung Ah Han, Eun‐Gyoung Hong, Jun Goo Kang, Choon Hee Chung, Jong Chul Won, Eon Ju Jeon, Jung‐Hwan Cho, Ho Chan Cho, Sin Gon Kim, Eun Seok Kang, So Hun Kim, Hae Jin Kim, In‐Kyung Jeong, Sung Wan Chun, Young Min Cho   +15 more
wiley   +1 more source

Validity of measures of pain and symptoms in HIV/AIDS infected households in resources poor settings: results from the Dominican Republic and Cambodia

BMC Palliative Care, 2006
Background HIV/AIDS treatment programs are currently being mounted in many developing nations that include palliative care services. While measures of palliative care have been developed and validated for resource rich settings, very little work exists ...
Morineau Guy, Wolf R Cameron, Pappas Gregory, Harding Richard   +3 more
doaj   +1 more source

A randomized, double‐blind, placebo‐controlled, multicenter study to evaluate the efficacy and safety of adjunctive cenobamate in Asian patients with focal seizures

Epilepsia, EarlyView.
A randomized, double‐blind, placebo‐controlled, multicenter study to evaluate the efficacy and safety of adjunctive cenobamate in Asian patients with focal seizures. Abstract Objectives This randomized, double‐blind, placebo‐controlled study (NCT04557085), conducted in China, Japan, and the Republic of Korea, evaluated the efficacy and safety of ...
Sang Kun Lee, Peimin Yu, Eunyeong Choe, Louis Ferrari, Kyoung Heo, Seung Bong Hong, Zhen Hong, Koji Iida, Yong Heui Jeon, Jiwon Jung, Marc Kamin, Kensuke Kawai, Ji Hyun Kim, Myung Won Kim, Xiaorong Liu, Jungshin Park, William E. Rosenfeld, Takamichi Yamamoto, Dong Zhou, Suiqiang Zhu, Sunita N. Misra   +20 more
wiley   +1 more source

Informational Odds Ratio: A Useful Measure of Epidemiologic Association in Environment Exposure Studies

Environmental Health Insights, 2012
The informational odds ratio (IOR) measures the post-exposure odds divided by the pre-exposure odds (ie, information gained after knowing exposure status). A desirable property of an adjusted ratio estimate is collapsibility (ie, the combined crude ratio
Jimmy T. Efird, Suzanne Lea, Amanda Toland, Christopher J. Phillips   +3 more
doaj   +1 more source

Métodos para estimar razão de prevalência em estudos de corte transversal Métodos para estimar razón de prevalencia en estudios de cohorte transversal Methods for estimating prevalence ratios in cross-sectional studies

Revista de Saúde Pública, 2008
OBJETIVO: Comparar empiricamente as regressões de Cox, log-binomial, Poisson e logística para estimar razões de prevalência em estudos de corte transversal.
Leticia M S Coutinho, Marcia Scazufca, Paulo R Menezes   +2 more
doaj   +1 more source

Early response rates with adjunctive cenobamate in uncontrolled focal seizures: Prospective analysis of a randomized, double‐blind, placebo‐controlled study in a multinational Asian population

Epilepsia, EarlyView.
Graphical representation of article highlights, including early response rates with adjunctive cenobamate. Abstract Objective To examine early responses to cenobamate therapy using prospective data from a dose–response study in Asian patients with focal seizures (YKP3089C035, C035) that employed a titration regimen starting at 12.5 mg/day.
Kensuke Kawai, Eunyeong Choe, Louis Ferrari, Kyoung Heo, Seung Bong Hong, Huapin Huang, Koji Iida, Yong Heui Jeon, Jiwon Jung, Marc Kamin, Ji Hyun Kim, Myung Won Kim, Sang Kun Lee, Songqing Pan, Jungshin Park, Pranoti Pradhan, William E. Rosenfeld, Huiqin Xu, Takamichi Yamamoto, Sunita N. Misra   +19 more
wiley   +1 more source

The Impact of Nutritional Status on Oral Health Outcomes and Management in Older Adults: A Systematic Review and Meta‐Analysis

Gerodontology, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis evaluated the relationship between nutritional status and the oral health of older adults (aged 75 years or older). The PECO focus question was, ‘What is the occurrence, association and impact of nutritional state on the oral health outcomes and its management in older adults?’ Methods A ...
Kittipit Srisanoi, Ines Wnuk, Sabrina Maniewicz, Gerry McKenna, Frauke Müller, Claudio Leles, Piero Papi, Jayne Woodside, Murali Srinivasan   +8 more
wiley   +1 more source

Multi-center clinical trials: Randomization and ancillary statistics

, 2008
The purpose of this paper is to investigate and develop methods for analysis of multi-center randomized clinical trials which only rely on the randomization process as a basis of inference.
Zelen, Marvin, Zheng, Lu
core   +1 more source