Results 121 to 130 of about 41,323 (225)

Effect of Intraoperative Regional Anesthesia on Postoperative Outcomes in Pediatric Cardiac Surgery—A Systematic Review of Randomized Controlled Trials

open access: yesPediatric Anesthesia, Volume 36, Issue 8, Page 899-907, August 2026.
ABSTRACT Objective To conduct a meta‐analysis of postoperative outcomes following the use of regional anesthesia in pediatric cardiac surgery. Data Sources We searched PubMed (MEDLINE), Web of Science, CINAHL, CENTRAL, and Scopus in December 2024 (PROSPERO: CRD420025635423; registered January 2025).
Katariina Hiisivuori   +3 more
wiley   +1 more source

Authors' reply: Continuity corrections with Mantel-Haenszel estimators in Cochrane reviews. [PDF]

open access: yesRes Synth Methods
Tsujimoto Y   +5 more
europepmc   +1 more source

Physiological cardiotocography interpretation and neonatal morbidity: A historical pre–post cohort study in a tertiary perinatal center

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 8, Page 1578-1586, August 2026.
In this historical pre–post cohort study, the implementation of physiological cardiotocography (PCI) interpretation was associated with reduced neonatal morbidity, neonatal acidosis, and neonatal unit admission. Adjusted cesarean section rates did not increase, supporting PCI as a promising approach to intrapartum fetal surveillance.
Sophia Andres   +8 more
wiley   +1 more source

Anticoagulation Strategies in Adults Undergoing Extracorporeal Membrane Oxygenation: A Systematic Review and Meta‐Analysis

open access: yesArtificial Organs, Volume 50, Issue 8, Page 1103-1117, August 2026.
In this meta‐analysis of 2 775 adult ECMO patients from non‐randomized studies, direct thrombin inhibitors and low‐molecular‐weight heparins demonstrated a favorable efficacy and safety profile over unfractionated heparin. These findings suggest them to be effective alternatives to unfractionated heparin, underscoring the urgent need for randomized ...
Vincenz Scharner   +7 more
wiley   +1 more source

Bowel Habits and Functional Constipation in Healthy Children—A Longitudinal Birth‐Cohort Study

open access: yesActa Paediatrica, Volume 115, Issue 8, Page 1672-1680, August 2026.
ABSTRACT Aim Functional constipation is common during childhood. Parents' concerns about their child's bowel habits are often the reason for seeking healthcare. We aim to report data on normal bowel habits, prevalence of functional constipation, long‐term outcome, and a search for risk factors in children during the first 2.5 years of life.
C. Gatzinsky   +5 more
wiley   +1 more source

Dual pharmacological targeting of coactivator‐associated arginine methyltransferase 1 (CARM1) and salt inducible kinase (SIK) drives ketogenesis in both hepatocytes and mice

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 15, Page 4399-4415, August 2026.
Abstract Background and Purpose Ketone bodies are liver‐derived circulating energy metabolites that positively impact most hallmarks of ageing. Ketone bodies increase during calorie restriction and fasting, two of the more widely perceived methods to increase health span.
Tábata Bergonci   +15 more
wiley   +1 more source

Semaglutide Injection in Indian Patients With Type 2 Diabetes Mellitus: A Randomised, Phase III, Active‐Controlled Study

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7094-7103, August 2026.
ABSTRACT Aim To evaluate the efficacy, safety and immunogenicity of semaglutide injection (synthetic) (Test group) compared with the Reference semaglutide injection [Ozempic, (Reference group)] in Indian patients with Type 2 diabetes mellitus (T2DM).
Unnikrishnan Ambika Gopalakrishnan   +33 more
wiley   +1 more source

Acute non-alcoholic caffeinated beverage consumption as a trigger for cryptogenic ischemic stroke in the young: findings from the SECRETO study. [PDF]

open access: yesJ Neurol
Ferdinand P   +28 more
europepmc   +1 more source

Long‐term efficacy of abrocitinib in patients with moderate‐to‐severe atopic dermatitis to 2 years

open access: yesJournal of the European Academy of Dermatology and Venereology, Volume 40, Issue 8, Page 1372-1381, August 2026.
JADE EXTEND is an ongoing phase 3, long‐term extension study of previous abrocitinib trials. Patients were adults and adolescents ≥12 years with moderate‐to‐severe atopic dermatitis. Long‐term abrocitinib treatment resulted in clinically meaningful outcomes and improvements in patient‐reported outcomes up to Week 112 in patients with moderate‐to‐severe
Melinda J. Gooderham   +14 more
wiley   +1 more source

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