Results 121 to 130 of about 42,816 (232)

LncRNA A1BGAS1 Serves as a Tumor Suppressor in Non‐Small Cell Lung Cancer by Modulating the Expression of miR‐3942‐5P

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.
This study verified the potential of A1BG‐AS1 to serve as a molecular biomarker for NSCLC prognosis. Mechanistically, A1BG‐AS1 exerts inhibitory effects on NSCLC cell proliferation, migration, and invasion and exerts a promoting effect on apoptosis via direct targeting and downregulation of miR‐3942‐5p.
Jiahui Du   +3 more
wiley   +1 more source

Authors' reply: Continuity corrections with Mantel-Haenszel estimators in Cochrane reviews. [PDF]

open access: yesRes Synth Methods
Tsujimoto Y   +5 more
europepmc   +1 more source

Switching From Originator to Biosimilar Infliximab in Pediatric Inflammatory Bowel Disease: A Systematic Review and Meta‐Analysis

open access: yesJCC Plus, Volume 1, Issue 6, November 2026.
In this meta‐analysis of eight studies (508 children with inflammatory bowel disease), switching from originator to biosimilar infliximab preserved clinical remission, drug exposure, and immunogenicity, with high treatment persistence and no signal of efficacy or safety loss. Biosimilar switching appears a safe, effective option in pediatric IBD.
Douglas Amaral da Silva Menegazzo Miotto   +4 more
wiley   +1 more source

Awake Blue Light vs. KTP Laser Treatment for Vocal Fold Lesions: A Randomized Controlled Trial

open access: yesThe Laryngoscope, Volume 136, Issue 11, Page 4914-4920, November 2026.
In this pilot randomized controlled clinical trial, the BL laser demonstrated clinical efficacy comparable to the KTP laser for office‐based treatment of benign vocal fold lesions. Both laser modalities were associated with significant improvements in patient‐perceived voice handicap, minimal post‐procedural pain, and favorable stroboscopic outcomes ...
R. Jun Lin   +4 more
wiley   +1 more source

Pre‐Extubation Low‐Dose Propofol in Pediatric Ear, Nose, and Throat Procedures: A Meta‐Analysis With Trial Sequential Analysis

open access: yesPediatric Anesthesia, Volume 36, Issue 11, Page 1375-1386, November 2026.
ABSTRACT Background Post‐extubation emergence agitation (EA) is common in pediatric ear, nose, and throat (ENT) procedures and may lead to serious complications. Aims To assess the efficacy of low‐dose propofol administered before extubation, compared with placebo, for preventing EA, using meta‐analysis with trial sequential analysis (TSA).
Rafaela Silva   +8 more
wiley   +1 more source

Evaluating the Impact of Outcome Delay on the Efficiency of Sample Size Re‐Estimation

open access: yesPharmaceutical Statistics, Volume 25, Issue 6, November/December 2026.
ABSTRACT Sample size re‐estimation (SSR) can be a powerful tool to ensure that a clinical trial meets its pre‐specified power requirements when uncertainty regarding a design parameter exists at the planning stage. However, long‐term primary endpoints can be harmful to the efficiency of this trial design.
Aritra Mukherjee   +2 more
wiley   +1 more source

Association Between Lateral Placenta and Adverse Maternal and Perinatal Outcomes: A Systematic Review and Meta‐Analysis

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 12, Page 2081-2091, November 2026.
ABSTRACT Background Adverse maternal and perinatal outcomes such as preeclampsia, small‐for‐gestational age (SGA) and preterm birth remain major global health concerns. Beyond known high‐risk placental features, emerging evidence suggests lateral placenta to be associated with impaired uteroplacental blood flow resulting in placenta dysfunction and ...
Joseph Arkorful   +6 more
wiley   +1 more source

Olanzapine for the Prevention and Treatment of ICU Delirium: Protocol for a Systematic Review With Meta‐Analysis

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 10, November 2026.
ABSTRACT Background Intensive care unit (ICU) delirium is a multifactorial acute brain dysfunction associated with prolonged hospitalization, increased morbidity and mortality, and higher healthcare costs. Despite these substantial negative impacts of delirium, the optimal prevention and treatment strategies are unclear.
Benedikte Liebetrau   +5 more
wiley   +1 more source

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