Results 101 to 110 of about 42,816 (232)

A randomized phase 2 trial of socrodeucitinib in moderate‐to‐severe plaque psoriasis

Journal of the European Academy of Dermatology and Venereology, EarlyView.
In moderate‐to‐severe plaque psoriasis, socrodeucitinib (6 mg/12 mg) significantly outperformed placebo at week 12: PASI 75 response rates 28.6%/72.1% vs. 7.5%. Meanwhile, socrodeucitinib illustrated a favourable safety and tolerability profile, warranting further study.
Ling Han, Songmei Geng, Yangfeng Ding, Shifa Zhang, Xiaohua Wang, Fengming Hu, Jianguo Li, Chao Ci, Yayu Hu, Rixin Chen, Jianping Zhang, Xiaoyong Zhou, Aijun Chen, Chunlei Zhang, Tiechi Lei, Yanyan Feng, Yu Wang, Zudong Meng, Yan Zhou, Mingkai Ji, Wei Liu, Yunting Wu, Qianying Chen, Siyi Wang, Jinhua Xu   +24 more
wiley   +1 more source

Investigation of Theoretical Exams in Medical Faculties in Terms of Differential Item Functioning: Sample of Mersin University Medical Faculty

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2014
Purpose: Current study investigated whether the measurement tools utilized during medical faculty preclinical period to form the basis of pass-fail decisions taken for students included Differential Item Functioning for foreign and Turkish students ...
Huseyin Selvi, Ibrahim Bashan, Gonul Aslan   +2 more
doaj  

Endoscopic Sphincterotomy Prior to Biliary Stenting for Malignant Biliary Obstruction: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aims ERCP‐guided biliary stenting is the usual palliative treatment for patients with unresectable malignant biliary obstruction (MBO). Previous studies suggested that ES prior to biliary stenting may not reduce the post‐ERCP pancreatitis (PEP) risk and may increase bleeding risk.
Sofia Coelho Meine, Gabriel de Oliveira Amaral, Mateus Rech Tedesco, João Pedro Schmitt, Gabrielle Knackfuss D'Aiuto, Gilmara Coelho Meine   +5 more
wiley   +1 more source

Use of Dual Orexin Receptor Antagonists for Insomnia and the Risk of Falls and Fractures: A Systematic Review and Meta‐Analysis

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Falls are the leading cause of injury in older adults. Sedative‐hypnotic use is a known risk factor, but their use for insomnia continues to be common. Dual orexin receptor antagonists (DORAs) are a new, potentially safer class of medications for insomnia.
Arianna Paolone, Shehraz Riar, Shajjan Vejayavarnan, Alexandra Papaioannou, George Ioannidis, Justin Lee   +5 more
wiley   +1 more source

GLP‐1 receptor agonists and serious adverse events: Evidence, uncertainty and clinical implications

Journal of Internal Medicine, EarlyView.
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists provide benefits in weight reduction, glycaemic control in Type 2 diabetes, and cardiovascular and renal outcomes. Their widespread use has given rise to concerns regarding rare but potentially serious adverse events.
Peter Ueda
wiley   +1 more source

Assessment fairness at the nexus of validity: Linking fairness threats to score meaning

Medical Education, EarlyView.
Abstract Introduction Nearly a century after Kelley's seminal work Interpretation of educational measurements, we revisit the concept of validity to argue that fairness is not a downstream equity add‐on but a core requirement throughout the assessment lifecycle.
Christina St‐Onge, Mélanie Marceau, Bruno D. Zumbo   +2 more
wiley   +1 more source

Differential item functioning analysis in large scale assessments: a case study for DIF in SABER 11

Large-scale Assessments in Education
Background Absence of differential item functioning (DIF) is an important piece of evidence to support inferences based on group comparisons of test results.
John Alexander Calderón, Nelson Andrés Rodríguez, Víctor H. Cervantes   +2 more
doaj   +1 more source

Assessing the Effectiveness of Workers' Selection Exams: The Case of the Bank of Italy

Oxford Bulletin of Economics and Statistics, EarlyView.
ABSTRACT High‐stakes exams can be used to rank and select candidates for job openings, and the ability of those selected hinges on the design of the exam. I propose a method to model candidates' performance to assess how effective the exam is at selecting high‐ability candidates.
Santiago Pereda‐Fernández
wiley   +1 more source

Medida del funcionamiento diferencial del ítem en el marco de la teoría de respuesta al ítem

Interdisciplinaria, 2007
En el estudio del funcionamiento diferencial del ítem (DIF - differential item functioning) la medición de su tamaño proporciona información relevante.
María Ester Aguerri, María Silvia Galibert, Gabriela Susana Lozzia, Facundo Juan Pablo Abal, Horacio Félix Attorresi   +4 more
doaj  

Cryoballoon Versus Radiofrequency Ablation for Persistent Atrial Fibrillation: Meta‐Analysis of Randomized Trials

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Introduction Pulmonary vein isolation (PVI) alone achieves modest arrhythmia freedom in persistent atrial fibrillation (PeAF). Cryoballoon ablation (CBA) offers a single‐shot alternative to radiofrequency ablation (RFA) that streamlines procedural workflow.
Harroop Bola, Aksaan Arif, Joshua J. Hon, Gayathri Giritharan, Prachur Khandelwal, Rodrick Avakian, Amar Rai, Kiran Haresh Kumar Patel, Fu Siong Ng   +8 more
wiley   +1 more source