Results 101 to 110 of about 41,213 (233)

Semaglutide Treatment in Young Adults Living With Type 2 Diabetes: A Post Hoc Analysis From the SUSTAIN and PIONEER Clinical Trials

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5787-5802, July 2026.
ABSTRACT Aims Young adults (aged ≤ 40 years) are underrepresented in clinical trials that investigate interventions for those living with Type 2 diabetes (T2D). This study evaluated the efficacy of semaglutide treatment in young adults with T2D by examining the effects on HbA1c and body weight (BW) during the SUSTAIN and PIONEER programmes compared to ...
Francesco Zaccardi   +8 more
wiley   +1 more source

Fluorosis en dentición temporal en un área con hidrofluorosis endémica Dental fluorosis in primary dentition in an endemic hydrofluorosis area

open access: yesSalud Pública de México, 2000
OBJETIVO: Determinar la prevalencia de fluorosis dental en la población infantil de la ciudad de San Luis Potosí, y su asociación con la concentración de flúor en agua de consumo y de orina.
Juan Pablo Loyola-Rodríguez   +3 more
doaj  

Association of Adverse Childhood Experiences and Metabolic Syndrome: A Systematic Review and Meta‐Analysis

open access: yesObesity Reviews, Volume 27, Issue 7, July 2026.
ABSTRACT Background The association between adverse childhood experiences (ACEs) and metabolic syndrome (MetS) across life course and its components (abdominal obesity, elevated blood pressure, dyslipidemia, and hyperglycemia) is poorly understood. Methods Three databases were screened for studies published January 2000–February 2024 that examined the ...
Joohan Kim   +4 more
wiley   +1 more source

Bovine tuberculosis history as a risk factor for recurrence in English cattle herds experiencing a breakdown

open access: yesVeterinary Record, Volume 198, Issue 12, Page e533-e542, 13–27 June 2026.
Abstract Background Bovine tuberculosis (TB) threatens cattle farming in England. Supplementing tuberculin skin testing with the interferon‐gamma blood test during TB incident (breakdown) management can enhance diagnostic sensitivity. We aimed to identify herds at greater risk of recurrence depending on their recent TB history to inform targeted ...
Daisy Duncan   +5 more
wiley   +1 more source

Long‐Term Anifrolumab Treatment Normalizes Hematologic Parameters and Several Serologic Markers in Patients With Systemic Lupus Erythematosus

open access: yesACR Open Rheumatology, Volume 8, Issue 6, June 2026.
Objective To evaluate the long‐term effects of anifrolumab on hematologic and serologic parameters over four years. Methods This analysis included 536 patients with moderate‐to‐severe systemic lupus erythematosus (SLE) who received intravenous anifrolumab 300 mg (n = 358) or placebo (n = 178) in the 52‐week, phase 3 TULIP‐1/2 trials (NCT02446912 and ...
Edward M. Vital   +9 more
wiley   +1 more source

Efficacy and Safety of Subcutaneous Anifrolumab in Systemic Lupus Erythematosus: A Randomized, Phase 3 Study

open access: yesArthritis &Rheumatology, Volume 78, Issue 6, Page 1258-1267, June 2026.
Objective The multinational, phase 3, double‐blind, placebo‐controlled TULIP‐SC trial evaluated the efficacy and safety of subcutaneous anifrolumab in adults who have moderate to severe systemic lupus erythematosus (SLE) activity, despite receiving standard therapy. Methods Adults with SLE received subcutaneous anifrolumab 120 mg or placebo once weekly
Susan Manzi   +12 more
wiley   +1 more source

Differential item functioning analysis in large scale assessments: a case study for DIF in SABER 11

open access: yesLarge-scale Assessments in Education
Background Absence of differential item functioning (DIF) is an important piece of evidence to support inferences based on group comparisons of test results.
John Alexander Calderón   +2 more
doaj   +1 more source

Efficacy and Safety of Baxdrostat for Hypertension: A Systematic Review and Meta‐Analysis of Three Phase 2/3 Randomized Controlled Trials

open access: yesClinical Cardiology, Volume 49, Issue 6, June 2026.
Baxdrostat: Effective blood pressure reduction with preserved cortisol levels. ABSTRACT Background Baxdrostat is a selective aldosterone synthase (CYP11B2) inhibitor for treatment‐resistant and uncontrolled hypertension, evaluated in phase 2/3 RCTs.
Rahul Falodia   +6 more
wiley   +1 more source

Medida del funcionamiento diferencial del ítem en el marco de la teoría de respuesta al ítem

open access: yesInterdisciplinaria, 2007
En el estudio del funcionamiento diferencial del ítem (DIF - differential item functioning) la medición de su tamaño proporciona información relevante.
María Ester Aguerri   +4 more
doaj  

Testosterone and docetaxel treatment effect on mortality risk in nonmetastatic high‐risk prostate cancer: A predictive biomarker analysis

open access: yesCancer, Volume 132, Issue 11, 1 June 2026.
Abstract Background Prostate cancer (PC) arising in patients with low testosterone is often more aggressive and less responsive to androgen deprivation therapy (ADT). This study evaluated whether baseline testosterone group (low vs. normal) modifies the mortality benefit of adding docetaxel to radiation therapy (RT) and ADT in nonmetastatic high‐risk ...
Johnathan Zeng   +7 more
wiley   +1 more source

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