Results 101 to 110 of about 41,213 (233)
ABSTRACT Aims Young adults (aged ≤ 40 years) are underrepresented in clinical trials that investigate interventions for those living with Type 2 diabetes (T2D). This study evaluated the efficacy of semaglutide treatment in young adults with T2D by examining the effects on HbA1c and body weight (BW) during the SUSTAIN and PIONEER programmes compared to ...
Francesco Zaccardi +8 more
wiley +1 more source
OBJETIVO: Determinar la prevalencia de fluorosis dental en la población infantil de la ciudad de San Luis Potosí, y su asociación con la concentración de flúor en agua de consumo y de orina.
Juan Pablo Loyola-Rodríguez +3 more
doaj
ABSTRACT Background The association between adverse childhood experiences (ACEs) and metabolic syndrome (MetS) across life course and its components (abdominal obesity, elevated blood pressure, dyslipidemia, and hyperglycemia) is poorly understood. Methods Three databases were screened for studies published January 2000–February 2024 that examined the ...
Joohan Kim +4 more
wiley +1 more source
Abstract Background Bovine tuberculosis (TB) threatens cattle farming in England. Supplementing tuberculin skin testing with the interferon‐gamma blood test during TB incident (breakdown) management can enhance diagnostic sensitivity. We aimed to identify herds at greater risk of recurrence depending on their recent TB history to inform targeted ...
Daisy Duncan +5 more
wiley +1 more source
Objective To evaluate the long‐term effects of anifrolumab on hematologic and serologic parameters over four years. Methods This analysis included 536 patients with moderate‐to‐severe systemic lupus erythematosus (SLE) who received intravenous anifrolumab 300 mg (n = 358) or placebo (n = 178) in the 52‐week, phase 3 TULIP‐1/2 trials (NCT02446912 and ...
Edward M. Vital +9 more
wiley +1 more source
Objective The multinational, phase 3, double‐blind, placebo‐controlled TULIP‐SC trial evaluated the efficacy and safety of subcutaneous anifrolumab in adults who have moderate to severe systemic lupus erythematosus (SLE) activity, despite receiving standard therapy. Methods Adults with SLE received subcutaneous anifrolumab 120 mg or placebo once weekly
Susan Manzi +12 more
wiley +1 more source
Differential item functioning analysis in large scale assessments: a case study for DIF in SABER 11
Background Absence of differential item functioning (DIF) is an important piece of evidence to support inferences based on group comparisons of test results.
John Alexander Calderón +2 more
doaj +1 more source
Baxdrostat: Effective blood pressure reduction with preserved cortisol levels. ABSTRACT Background Baxdrostat is a selective aldosterone synthase (CYP11B2) inhibitor for treatment‐resistant and uncontrolled hypertension, evaluated in phase 2/3 RCTs.
Rahul Falodia +6 more
wiley +1 more source
Medida del funcionamiento diferencial del ítem en el marco de la teoría de respuesta al ítem
En el estudio del funcionamiento diferencial del ítem (DIF - differential item functioning) la medición de su tamaño proporciona información relevante.
María Ester Aguerri +4 more
doaj
Abstract Background Prostate cancer (PC) arising in patients with low testosterone is often more aggressive and less responsive to androgen deprivation therapy (ADT). This study evaluated whether baseline testosterone group (low vs. normal) modifies the mortality benefit of adding docetaxel to radiation therapy (RT) and ADT in nonmetastatic high‐risk ...
Johnathan Zeng +7 more
wiley +1 more source

