Adjunctive linaclotide improves bowel cleansing and patient experience in polyethylene glycol-based bowel preparation. [PDF]
Chen X, He X, Li P.
europepmc +1 more source
ABSTRACT Background Elderly patients with moderate‐to‐severe atopic dermatitis (AD) often exhibit more heterogeneous inflammatory profiles compared with younger adults. To evaluate the efficacy and safety of stapokibart, an anti‐interleukin‐4 receptor α subunit (IL‐4Rα) monoclonal antibody, in different age subgroups.
Yan Zhao +26 more
wiley +1 more source
Point-of-care testing reduces antibiotic prescribing for adults with community-acquired pneumonia: a systematic review and meta-analysis. [PDF]
Ji W +8 more
europepmc +1 more source
Apremilast in Japanese patients with palmoplantar pustulosis: A randomized, Phase 3 trial
In this Phase 3 trial of Japanese patients with moderate to severe PPP (NCT05174065), significantly more patients achieved PPPASI‐50 at Week 16 with apremilast versus placebo. Patient‐reported outcomes, including pruritus and pain/discomfort, also showed significantly greater decreases at Week 16 with apremilast versus placebo.
Tadashi Terui +15 more
wiley +1 more source
Ligation Versus Repair of Isolated Traumatic Peripheral Venous Injury: A Systematic Review and Meta-Analysis. [PDF]
Shahzad N +3 more
europepmc +1 more source
Bimekizumab efficacy and safety in Chinese patients with psoriasis in the BE SHINING Phase 3 study
In Chinese patients with moderate to severe plaque psoriasis, bimekizumab treatment was well tolerated and led to significantly higher clinical response rates versus placebo, including complete skin clearance. These findings were consistent with global studies and suggest that bimekizumab is an effective treatment option for Chinese people living with ...
Lin Cai +11 more
wiley +1 more source
Comparative Effectiveness of Cytisinicline and Varenicline for Smoking Cessation: A Matching-Adjusted Indirect Comparison (MAIC). [PDF]
Rubinstein M +3 more
europepmc +1 more source
ABSTRACT Aims Identify and describe patient engagement interventions used to improve medication management in older adults during transitions of care. Design A mixed‐methods systematic review. Methods A comprehensive search of all study designs was conducted.
Kelly Ottosen +8 more
wiley +1 more source
Double posteromedial portal arthroscopy vs. other arthroscopic techniques for Baker's cyst: a systematic review and meta-analysis. [PDF]
Li F, Fu X, Yu J, Chen J, Xu L, Xiao J.
europepmc +1 more source
ABSTRACT Background and Aims Primary sclerosing cholangitis (PSC) is an immune‐mediated cholestatic liver disease. Liver transplantation (LT) remains the only definitive treatment for patients with advanced disease. However, recurrence of PSC (rPSC) after LT is still a significant clinical challenge.
Isabelle Castro Vitor +10 more
wiley +1 more source

