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Hypermutation in mantle cell lymphoma does not indicate a clinical or biological subentity. [PDF]
, 2009 Contains fulltext :
80422.pdf (Publisher’s version ) (Open Access)Mantle cell lymphoma is a prime example of a well-defined entity based on morphology, phenotype, genetics and also clinical features.Hebeda, Konnie, Kluin, P.M., Krieken, J.H.J.M. van, Schraders, M., Schuuring, Ed, Hebeda, K.M., Groenen, P.J.T.A., Oeschger, S., Schuuring, Ed; id_orcid, Schuuring, E., van Krieken, Johan H. J. M., Oeschger, Sabine, Schraders, Margit, Groenen, Patricia J. T. A., Kluin, Philip M., Hansmann, M.L., Hansmann, Martin-Leo +16 morecore +1 more sourceComparison of intestinal histopathological changes following teclistamab, BCMA‐directed CAR T, CD19‐directed CAR T and rituximab therapies
Histopathology, EarlyView.This is a retrospective review of intestinal tract biopsies from patients treated with various cellular immunotherapies (BCMA and CD19‐directed CAR T, teclistamab and rituximab therapies). We found distinct but overlapping histologic patterns across treatment groups, with lamina propria plasma cell depletion, crypt apoptotic bodies and active ...Olivia J Leung, Esther Baranov, Isairis Peralta Valerio, Robin Collingwood, Natalie Respond, Don Siegel, Pooja Devi, Kristen M. Stashek +7 morewiley +1 more sourceA B-cell receptor-related gene signature predicts survival in mantle cell lymphoma: results from the Fondazione Italiana Linfomi MCL-0208 trial
Haematologica, 2018 Mantle cell lymphoma patients have variable clinical courses, ranging from indolent cases that do not require immediate treatment to aggressive, rapidly progressing diseases.Riccardo Bomben, Simone Ferrero, Tiziana D’Agaro, Michele Dal Bo, Alessandro Re, Andrea Evangelista, Angelo Michele Carella, Alberto Zamò, Umberto Vitolo, Paola Omedè, Chiara Rusconi, Luca Arcaini, Luigi Rigacci, Stefano Luminari, Andrea Piccin, Delong Liu, Adrian Wiestner, Gianluca Gaidano, Sergio Cortelazzo, Marco Ladetto, Valter Gattei +20 moredoaj +1 more sourceICSH Guidance on Bone Marrow Examination and Reporting
International Journal of Laboratory Hematology, EarlyView.ABSTRACT
Examination of the bone marrow (BM) remains fundamental to the diagnosis, classification, prognostication, and monitoring of hematolymphoid and other disorders affecting blood cell production. Since publication of the International Council for Standardization in Haematology (ICSH) guideline in 2008, advances in diagnostic technologies, disease Wendy N. Erber, Alexandar Tzankov, Olga Pozdnyakova, Hiromichi Matsushita, Gina Zini, Leonie Saft, on behalf of the International Council for Standardization in Haematology +6 morewiley +1 more sourceEmerging role of SOX11 in mantle cell lymphoma
, 2015 Venera Kuci,1,2,* Lena Nordström,1,2,* Mats Jerkeman,3 Sara Ek1,2 1Department of Immunotechnology, Lund University, Lund, Sweden; 2CREATE Health, Lund University, Lund, Sweden; 3Department of Oncology, Lund University, Lund, Sweden *These authors ...Jerkeman M, Ek S, Kuci V, Nordström Lcore Molecular diagnosis of malignant lymphoma : mantle cell lymphoma, anaplastic large cell lymphoma, and marginal zone B-cell lymphoma of malt [PDF]
, 2006 2006-01Malignant lymphoma is a heterogeneous category embracing three major types of lymphoid neoplasms: B cell neoplasms, T and NK cell neoplasms, and Hodgkin lymphoma.Nakamura, Shigeo, 長坂, 徹郎, 榊原, 綾子, Kawai, Kumi, 下山, 芳江, Nagasaka, Tetsuro, 川井, 久美, Sakakibaya, Ayako, Shimoyama, Yoshie +8 morecore +1 more sourceNodular lymphocyte predominant hodgkin lymphoma and T cell/histiocyte rich large B cell lymphoma : endpoints of a spectrum of one disease? [PDF]
, 2013 In contrast to the commonly indolent clinical behavior of nodular lymphocyte predominant Hodgkin lymphoma (NLPHL), T cell/histiocyte rich large B cell lymphoma (THRLBCL) is frequently diagnosed in advanced clinical stages and has a poor prognosis ...Benjamin Rengstl, Sebastian Newrzela, Randy Gascoyne, Xavier Sagaert (482298), Xavier Sagaert, Hartmann, Sylvia, Martin-Leo Hansmann, Claudia Döring, Küppers, Ralf, Chris de Wolf-Peeters, Fabio Facchetti, Ralf Küppers, Fabio Facchetti (376587), Sylvia Hartmann, Rengstl, Benjamin, Hansmann, Martin-Leo, Christian Steidl, Sagaert, Xavier, Martin-Leo Hansmann (260067), Tousseyn, Thomas, Christian Steidl (482300), Ralf Küppers (260072), Thomas Tousseyn (482297), Chris de Wolf-Peeters (482299), Steidl, Christian, Claudia Döring (474984), Ponzoni, Maurilio, Randy Gascoyne (482301), Jakobus, Christina, Wolf-Peeters, Chris de, Benjamin Rengstl (482295), Sebastian Newrzela (482296), Gascoyne, Randy, Maurilio Ponzoni (126480), Döring, Claudia, Thomas Tousseyn, Christina Jakobus (482294), Christina Jakobus, Facchetti, Fabio, Sylvia Hartmann (260069), Newrzela, Sebastian, Maurilio Ponzoni +41 morecore +2 more sourcesEltrombopag Added to Standard Immunosuppressive Treatment as Front‐Line Therapy for Severe Aplastic Anemia: Long‐Term Outcomes of the Phase‐3 Randomized Superiority EBMT‐SAAWP RACE Study
American Journal of Hematology, Volume 101, Issue 10, Page 2520-2532, October 2026.ABSTRACT
The RACE study (NCT02009747) compared horse antithymocyte globulin (hATG) plus cyclosporine A (CsA) ± eltrombopag as initial immunosuppressive treatment (IST) for severe aplastic anemia. Here we report the final 2‐year analysis of this prospective randomized phase III study.Antonio M. Risitano, Simona Iacobelli, Austin Kulasekararaj, Marleen van Os, Sofie R. Terwel, Joe Tuffnell, Brian Piepenbroek, Morag Griffin, Constantijn J. M. Halkes, Christian Recher, Fiorenza Barraco, Edouard Forcade, Juan Carlos Vallejo, Beatrice Drexler, Jean‐Baptiste Mear, Roochi Trikha, Shreyans Gandhi, Anna Maria Raiola, L. G. M. Daenen, Marco R. de Groot, Etienne Daguindau, Erfan Nur, Wilma Barcellini, Nigel H. Russell, Louis Terriou, Anna Paola Iori, Walter Barberi, Anna Sureda, Isabel Sánchez‐Ortega, Blanca Xicoy, Isidro Jarque, James Cavenagh, Flore Sicre de Fontbrune, Camilla Frieri, Talha Munir, Jennifer M. L. Tjon, Suzanne Tavitian, Aline Praire, Laurence Clement, Florence Rabian, Luana Marano, Anita Hill, Elena Palmisani, Petra Muus, Serena Marotta, Fabiana Cacace, Marica Laurino, Jakob R. Passweg, Gérard Socié, Ghulam J. Mufti, Carlo Dufour, Régis Peffault de Latour, Severe Aplastic Anaemia Working Party of the EBMT +52 morewiley +1 more sourceTNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma [PDF]
, 2009 Proliferation and survival of Hodgkin and Reed/Sternberg (HRS) cells, the malignant cells of classical Hodgkin lymphoma (cHL), are dependent on constitutive activation of nuclear factor {kappa}B (NF-{kappa}B).Inga Vater, Giefing, Maciej, Vater, Inga, Hartmann, Sylvia, Martin-Leo Hansmann, Martin-Subero, Jose Ignacio, Bohle, Verena, Küppers, Ralf, Jens Stanelle, Ralf Küppers, Sylvia Hartmann, Gunhild Mechtersheimer, Hansmann, Martin-Leo, Gesk, Stefan, Jose Ignacio Martin-Subero, Stanelle, Jens, Verena Bohle, Siebert, Reiner, Roland Schmitz, Klapper, Wolfram, Maciej Giefing, Wolfram Klapper, Mechtersheimer, Gunhild, Schmitz, Roland, Stefan Gesk, Reiner Siebert +25 morecore +1 more source