Results 81 to 90 of about 23,301 (196)
Adhesion molecule profiles of B-cell non-Hodgkin's lymphomas in the leukemic phase
We evaluated the expression of 10 adhesion molecules on peripheral blood tumor cells of 17 patients with chronic lymphocytic leukemia, 17 with mantle-cell lymphoma, and 13 with nodal or splenic marginal B-cell lymphoma, all in the leukemic phase and ...
D.M. Matos +4 more
doaj
A rare case of breast carcinoma co-existing with axillary mantle cell lymphoma
Background Mantle cell lymphoma (MCL) is a rare variety of non-Hodgkin's lymphoma which originates from CD5+ B-cell population in the mantle zones of lymphoid follicles. Coexistence of such tumours in the axillary lymph nodes with invasive breast cancers
Scally John +3 more
doaj +1 more source
[Cytogenetics of mantle cell lymphoma].
To determine the type and rate of secondary chromosomal aberrations and role in pathogenesis of mantle cell lymphoma (MCL).Standard cytogenetic examination (SCE) and fluorescent in situ hybridization (FISH) with tests for 11q22/ATM, 13q14, 17p13/p53, 9p21/p16 and chromosome 12 centromere were made in 28 patients.Secondary chromosomal aberrations were ...
T N Obukhova +7 more
openaire +2 more sources
MYC in Oncogenesis and Therapeutic Implications
The MYC oncogene family (c‐MYC, N‐MYC, L‐MYC) functions as a central transcriptional hub orchestrating cancer progression through multiple interconnected pathways. This graphical abstract illustrates MYC's role as a multidimensional regulator positioned at the nexus of tumor microenvironment remodeling, metabolic reprogramming, and therapeutic ...
Na Zhang +5 more
wiley +1 more source
Synergy of NVP-BEZ235 and enzastaurin in mantle cell lymphoma
Mantle cell lymphoma (MCL) is a neoplasm classified as a B-cell malignancy, that accounts for approximately 3 to 8% of Non-Hodgkin’s lymphoma (NHL) cases diagnosed annually. MCL is difficult to treat and seldom considered cured.
Monica Civallero, Maria Cosenza
doaj +1 more source
Antibody–Drug Conjugates and Peptide–Drug Conjugates: Current Understandings and Future Perspectives
The graphic summarizes the design principles, intracellular trafficking, clinical progress, challenges, and future directions of antibody–drug conjugates (ADCs) and peptide–drug conjugates (PDCs). ADCs consist of a tumor‐targeting antibody, a chemical linker, and a potent payload, whereas PDCs use peptide ligands to deliver cytotoxic, radionuclide, or ...
Ruxi Zheng +9 more
wiley +1 more source
Abstract A 5‐year‐old, male neutered, Bengal‐cross cat presented with progressive neurological signs (ataxia and torticollis). Initial haematology, serum biochemistry and electrolytes (including calcium) were unremarkable; however, ammonia was markedly elevated.
Kerry E. Rolph, Tim Scase, Owen Davies
wiley +1 more source
What Is Your Diagnosis? Blood Smear From a Mixed‐Breed Dog
Veterinary Clinical Pathology, EarlyView.
Laura S. Peres +5 more
wiley +1 more source
A schematic summary of the population pharmacokinetic model of rituximab in treatment‐naïve Chinese DLBCL patients during induction therapy, along with key clinical implications. ABSTRACT This study aimed to establish and validate a population pharmacokinetic model for rituximab during induction therapy in treatment‐naive patients with diffuse large B ...
Wan‐Yi Zhou +5 more
wiley +1 more source
ABSTRACT The tumour microenvironment (TME) of relapsed/refractory (R/R) diffuse large B‐cell lymphoma (DLBCL) patients is associated with resistance of DLBCL cells to CD19 CAR‐T cells. How to improve TME in DLBCL and improve the efficacy of CAR‐T cell therapy remains to be further explored.
Yao Qi +6 more
wiley +1 more source

