A rare case of breast carcinoma co-existing with axillary mantle cell lymphoma
Background Mantle cell lymphoma (MCL) is a rare variety of non-Hodgkin's lymphoma which originates from CD5+ B-cell population in the mantle zones of lymphoid follicles. Coexistence of such tumours in the axillary lymph nodes with invasive breast cancers
Scally John +3 more
doaj +1 more source
A phase I study of carfilzomib in combination with ibrutinib for relapsed refractory mantle cell lymphoma [PDF]
Hun Ju Lee +5 more
openalex +1 more source
Telomere protein complexes and their role in lymphoid malignancies [PDF]
Telomeres are highly regulated and dynamic complexes that protect the genomic DNA and prevent the end of linear chromosomes from being misrecognized as a broken DNA.
Dos Santos, Patricia Carolina +2 more
core
Summary A high unmet need for novel, safe and effective therapies exists among older patients with non‐Hodgkin lymphoma (NHL). We report safety and efficacy of mosunetuzumab in a subgroup analysis of a phase I/II study, which examined the prognostic impact of age in 218 patients with relapsed/refractory (R/R) B‐cell NHL (B‐NHL; ≥65 years, n = 102; <65 ...
Swetha Kambhampati Thiruvengadam +11 more
wiley +1 more source
Coexistent Primary Lung Adenocarcinoma and Mantle Cell Lymphoma: A Case Report [PDF]
Masooma Aqeel +2 more
openalex +1 more source
Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas [PDF]
Integrative genomic and gene-expression analyses have identified amplified oncogenes in B-cell non-Hodgkin lymphoma (B-NHL), but the capability of such technologies to localize tumor suppressor genes within homozygous deletions remains unexplored.
Agirre-Ena, X. (Xabier) +20 more
core
Artificial intelligence for risk assessment and outcome prediction in malignant haematology
Machine learning models allow for dynamic and scalable risk stratification and outcome prediction. Different modalities of data such as electronic health records, patient genetics or laboratory results can be used as input. ML models autonomously select features weighing their prognostic value. Methods of model explainability in feature selection allow
Jan‐Niklas Eckardt +3 more
wiley +1 more source
Extreme Peripheral Blood Plasmacytosis Mimicking Plasma Cell Leukemia as a Presenting Feature of Angioimmunoblastic T-Cell Lymphoma (AITL). [PDF]
Angioimmunoblastic T-cell lymphoma (AITL) is one of four major subtypes of nodal peripheral T cell lymphoma, characterized by its cell of origin, the follicular helper T-cell (TFH).
Alpdogan, Onder +7 more
core +1 more source
The heat shock protein 90 inhibitor 17‐AAG induces cell cycle arrest and apoptosis in mantle cell lymphoma cell lines by depleting cyclin D1, Akt, Bid and activating caspase 9 [PDF]
Georgios Georgakis, Yang Li, Anas Younes
openalex +1 more source
Role of Frailty in Assessing Eligibility for CAR T‐Cell Therapy in Haematology
ABSTRACT Background and Objectives Frailty is a key consideration in determining whether a patient is robust enough for CAR T‐cell therapy; however, it should not represent a barrier to treatment. Our study aimed to describe the extent of research concerning frailty in haematology adult and paediatric patients being considered for CAR T‐cell therapy ...
Jennifer Clesham +4 more
wiley +1 more source

