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Mantle Cell Lymphoma: An Update
Leukemia & Lymphoma, 1992Mantle cell lymphoma is a distinctive pathologic entity that incorporates the previous histopathologic categories of centrocytic lymphoma and lymphocytic lymphoma of intermediate differentiation. These lymphomas are characterized by common histologic and immunologic characteristics that suggest derivation from the follicular mantle zone.
Elaine S. Jaffe +3 more
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SOX11, a key oncogenic factor in mantle cell lymphoma
Current opinion in hematology, 2018Purpose of review SOX11 has emerged as a key transcription factor in the pathogenesis of mantle cell lymphoma (MCL) whereas it is not expressed in normal B cells or virtually in any other mature B-cell neoplasm. This review will examine the role of SOX11
R. Beekman, V. Amador, E. Campo
semanticscholar +1 more source
Clinical Lymphoma Myeloma and Leukemia, 2017
Mr HK is a 67-year-old Caucasian man with a past medical history of hypertension. He presented to his primary care physician’s office in June 2014 with 3 months’ history of fever, fatigue, and an enlarged cervical lymph node.
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Mr HK is a 67-year-old Caucasian man with a past medical history of hypertension. He presented to his primary care physician’s office in June 2014 with 3 months’ history of fever, fatigue, and an enlarged cervical lymph node.
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Lenalidomide for mantle cell lymphoma
Expert Review of Hematology, 2015Mantle cell lymphoma accounts for 6% of all non-Hodgkin lymphomas. It is a biologically and clinically heterogeneous disease and treatment may be difficult, since most patients present at an older age, being unable to undergo intensive chemotherapy. Lenalidomide is an approved medication for relapsed mantle cell lymphoma in patients who received at ...
Alan P Skarbnik, Andre Goy
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2019
Mantle cell lymphoma (MCL) of the ocular adnexa does not differ from systemic mantle cell lymphoma in its biological and clinical behaviour. As the name suggests, it arises from the mantle zone of the lymphoid follicles. It is a mature B-cell lymphoma, which is much less common than the other subtypes of B-cell lymphomas, and has an aggressive clinical
Bingcheng Wu +5 more
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Mantle cell lymphoma (MCL) of the ocular adnexa does not differ from systemic mantle cell lymphoma in its biological and clinical behaviour. As the name suggests, it arises from the mantle zone of the lymphoid follicles. It is a mature B-cell lymphoma, which is much less common than the other subtypes of B-cell lymphomas, and has an aggressive clinical
Bingcheng Wu +5 more
openaire +4 more sources
Histopathology of Mantle Cell Lymphoma
Seminars in Hematology, 2011Mantle cell lymphoma (MCL) is a relatively rare lymphoma, accounting for less than 10% only of all lymphomas. Its morphology is quite homogeneous, but it varies strikingly in about 10% of the cases, making the diagnosis of MCL challenging for histopathologists. The definition of the disease was greatly influenced by the discovery of the translocation t(
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Treatment of Mantle-Cell Lymphoma
New England Journal of Medicine, 2022Burhan, Ferhanoglu +2 more
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2015
Mantle cell lymphoma (MCL) is a well-defined lymphoid malignant disease characterized by a proliferation of mature B lymphocytes expressing CD5. This rare lymphoma regroups in fact a spectrum of morphological, phenotypic, and clinical pathologies with at least three diseases: the classical nodal MCL, the most common entity, the indolent leukemic ...
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Mantle cell lymphoma (MCL) is a well-defined lymphoid malignant disease characterized by a proliferation of mature B lymphocytes expressing CD5. This rare lymphoma regroups in fact a spectrum of morphological, phenotypic, and clinical pathologies with at least three diseases: the classical nodal MCL, the most common entity, the indolent leukemic ...
openaire +2 more sources