Results 81 to 90 of about 268,751 (268)

Validation, revision and extension of the Mantle Cell Lymphoma International Prognostic Index in a population-based setting

Haematologica, 2010
Background The aim of this study was to validate the Mantle Cell Lymphoma International Prognostic Index in a population-based cohort and to study the relevance of its revisions.Design and Methods We analyzed data from 178 unselected patients with stage ...
Saskia A.M. van de Schans, Maryska L.G. Janssen-Heijnen, Marten R. Nijziel, Ewout W. Steyerberg, Dick Johan van Spronsen   +4 more
doaj   +1 more source

The Evolution and Recent Advances in Diagnostic Criteria for Idiopathic Multicentric Castleman Disease

American Journal of Hematology, Volume 100, Issue 11, Page 2064-2073, November 2025.
Idiopathic Multicentric Castleman Disease. ABSTRACT Idiopathic multicentric Castleman disease (iMCD) is a rare cytokine‐driven disorder characterized by systemic inflammation, organ dysfunction, and altered lymph node microscopic architecture. Over the past decade, diagnostic criteria have evolved significantly, integrating clinical, histopathological,
FNU Alnoor, Nicholas C. Spies, Jyoti Kumar, Peyman Samghabadi, Oscar Silva, Matt X. Luo, Karen M. Chisholm, Jingjing Zhang, Alexandra Rangel, David Ng, Peng Li, Robert S. Ohgami   +11 more
wiley   +1 more source

A B-cell receptor-related gene signature predicts survival in mantle cell lymphoma: results from the Fondazione Italiana Linfomi MCL-0208 trial

Haematologica, 2018
Mantle cell lymphoma patients have variable clinical courses, ranging from indolent cases that do not require immediate treatment to aggressive, rapidly progressing diseases.
Riccardo Bomben, Simone Ferrero, Tiziana D’Agaro, Michele Dal Bo, Alessandro Re, Andrea Evangelista, Angelo Michele Carella, Alberto Zamò, Umberto Vitolo, Paola Omedè, Chiara Rusconi, Luca Arcaini, Luigi Rigacci, Stefano Luminari, Andrea Piccin, Delong Liu, Adrian Wiestner, Gianluca Gaidano, Sergio Cortelazzo, Marco Ladetto, Valter Gattei   +20 more
doaj   +1 more source

A phase 1 trial of SGN-CD70A in patients with CD70-positive diffuse large B cell lymphoma and mantle cell lymphoma

Investigational new drugs, 2018
SummaryPurpose This first-in-human study evaluated SGN-CD70A, an antibody-drug conjugate (ADC) directed against the integral plasma membrane protein CD70 and linked to a pyrrolobenzodiazepine (PBD) dimer, in patients with relapsed or refractory (R/R ...
T. Phillips, P. Barr, Steven I. Park, K. Kolibaba, P. Caimi, S. Chhabra, E. Kingsley, T. Boyd, Robert Chen, A. Carret, E. Gartner, Hong Li, Cindy Yu, David C. Smith   +13 more
semanticscholar   +1 more source

Diffuse Large B‐Cell Lymphoma of the Thyroid in a Patient With Hashimoto Thyroiditis: A Diagnostic Dilemma

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Primary thyroid lymphoma (PTL) is a rare malignancy, comprising 1%–5% of thyroid cancers and 2%–5% of extranodal lymphomas, with diffuse large B‐cell lymphoma (DLBCL) being the most common subtype. PTL often coexists with Hashimoto thyroiditis, leading to diagnostic delays.
Shravya Singh Karki, Shivam Pandey, Smriti Karki, Deepak Paudel, Chahana Pathak   +4 more
wiley   +1 more source

Spontaneous Splenic Rupture and Rituximab-Induced Acute Thrombocytopenia in a Patient with High-Risk Mantle Cell Lymphoma

Case Reports in Hematology, 2019
Mantle cell lymphoma is a relatively rare type of mature B-cell non-Hodgkin’s lymphoma with an incidence of approximately 8 cases per million persons per year.
Jared Williams, Shingi Chiruka
doaj   +1 more source

The Addition of the BTK Inhibitor Ibrutinib to Anti-CD19 Chimeric Antigen Receptor T Cells (CART19) Improves Responses against Mantle Cell Lymphoma

Clinical Cancer Research, 2016
Purpose: Responses to therapy with chimeric antigen receptor T cells recognizing CD19 (CART19, CTL019) may vary by histology. Mantle cell lymphoma (MCL) represents a B-cell malignancy that remains incurable despite novel therapies such as the BTK ...
M. Ruella, S. Kenderian, O. Shestova, J. Fraietta, Sohail Qayyum, Qian Zhang, M. Maus, Xiaobin Liu, S. Nunez-Cruz, M. Klichinsky, O. Kawalekar, M. Milone, S. Lacey, A. Mato, S. Schuster, M. Kalos, C. June, S. Gill, M. Wasik   +18 more
semanticscholar   +1 more source

Polatuzumab vedotin and CD79B: A study of efficacy in R‐CHOP‐resistant diffuse large B‐cell lymphoma

British Journal of Haematology, EarlyView.
Nicolas Munz, Alberto J. Arribas, Roberta Bordone Pittau, Federico Simonetta, Georg Stussi, Francesco Bertoni   +5 more
wiley   +1 more source

Routine Monitoring of CAR‐T‐Cells Expansion and Persistence in Patients With Aggressive Large B‐Cell Lymphoma by Flow Cytometry: A Single‐Center Experience

Hematological Oncology, Volume 43, Issue 6, November 2025.
ABSTRACT This retrospective, single‐center study evaluated routine flow cytometry (FC) monitoring of CAR‐T‐cells in 45 patients with aggressive large B‐cell lymphoma (LBCL). CAR‐T‐cells expansion was assessed from Day 0 to Month 12. Peak expansion occurred on Day 7 after axi‐cel (median 39.3% of total lymphocytes; 87 cells/mm3) and Day 10 for tisa‐cel (
Alexandra Zduniak, Jérémie Martinet, Emilie Lévêque, Stéphanie Becker, David Tonnelet, Elodie Dos Santos, Claire Leroy, Mustafa Alani, Jean Rouvet, Marine Brousseau, Camille Giverne, Alexis Cuffel, Serge Jacquot, Arnaud Roucheux, Alice Veuiller, Nicolas Lecornu, Misa Eugene Norbert, Olivier Boyer, Hervé Tilly, Fabrice Jardin, Jean‐Baptiste Latouche, Vincent Camus   +21 more
wiley   +1 more source

Machine Learning for Prediction of High‐Risk Hospitalizations in Lymphoma Patients: A Danish Population‐Based Study

European Journal of Haematology, Volume 115, Issue 5, Page 443-453, November 2025.
ABSTRACT Objective Infections are a leading cause of hospitalization in patients treated for lymphoma and can be life‐threatening. This study developed a machine learning (ML)‐based risk stratification method to classify infection‐related hospitalizations (IRH) into serious‐IRH (S‐IRH) and non‐serious‐IRH (NS‐IRH).
Alexander Djupnes Fuglkjaer, Deniz Kenan Kilic, Mathias Holmsgaard Eskesen, Mikkel Runason Simonsen, Laurids Østergaard Poulsen, Carsten Utoft Niemann, Paw Jensen, Kirstine Kobberøe Søgaard, Mikkel Werling, Frederik Christensen, Izabela Ewa Nielsen, Tarec Christoffer El‐Galaly   +11 more
wiley   +1 more source