Results 51 to 60 of about 96,005 (268)
Advanced Science, EarlyView.In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen +15 more
wiley +1 more source
The role of elasticity in slab bending [PDF]
, 2014 International audiencePrevious studies showed that plate rheology exerts a dominant control on the shape and velocity of subducting plates. Here, we perform a systematic investigation of the role of elasticity in slab bending, using fully dynamic 2-D ...
Gabriele Morra +4 more
core +2 more sources
Advanced Science, EarlyView.ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley +1 more source
Constraining Mantle Viscosity Structure From a Statistical Analysis of Slab Stagnation Events
Geochemistry, Geophysics, Geosystems, 2020 The viscosity structure of Earth's mantle, even the 1‐D radial viscosity profile, remains not well constrained. The dynamics of the subducting slabs is strongly affected by, and can be used to constrain, the viscosity structure of the mantle.
Yongming Wang, Mingming Li
doaj +1 more source
Linking the evolution of terrestrial interiors and an early outgassed atmosphere to astrophysical observations [PDF]
, 2019 A terrestrial planet is molten during formation and may remain so if subject to intense insolation or tidal forces. Observations continue to favour the detection and characterisation of hot planets, potentially with large outgassed atmospheres. We aim to
Bower, Dan J. +5 more
core +3 more sources
Advanced Science, EarlyView.. ABSTRACT Colloidal quantum dots (CQDs) based on II–V semiconductors offer attractive optical absorption and carrier transport properties for infrared optoelectronics, yet their device‐relevant electronic behavior remains poorly understood. In particular, Cd3P2 CQDs have been constrained by limited control over nanocrystal growth and carrier polarity.
Ha‐Chi V. Tran +10 more
wiley +1 more source
Mantle plumes: Dynamic models and seismic images [PDF]
Geochemistry, Geophysics, Geosystems, 2007 Different theories on the origin of hot spots have been debated for a long time by many authors from different fields, and global‐scale seismic tomography is probably the most effective tool at our disposal to substantiate, modify, or abandon the mantle‐plume hypothesis.
Boschi L, Becker TW, Steinberger B
openaire +6 more sources
Self-gravity, self-consistency, and self-organization in geodynamics and geochemistry [PDF]
, 2005 The results of seismology and geochemistry for mantle structure are widely believed to be discordant, the former favoring whole-mantle convection and the latter favoring layered convection with a boundary near 650 km.
Anderson, Don L.
core
American Journal of Hematology, EarlyView.ABSTRACT Mantle cell lymphoma (MCL) is a B‐cell malignancy with a chronically relapsing clinical course and pronounced genetic heterogeneity. To investigate the clonal dynamics underlying early disease relapse, we performed single‐cell RNA sequencing of paired tumor samples collected at diagnosis and at first relapse. Inference of copy number variants (
Dmitry Manakov +14 more
wiley +1 more source
Mantle dynamics and volcanism emplacement in the Azores [PDF]
, 2012 The Azores plateau is a triangular shaped topographic feature encompassing the boundary zone where three major tectonic plates (EU, NU and NA) meet. The eastern side of the plateau is delimited by two major tectonic discontinuities: the Mid Atlantic ...
Adam, Claudia +4 more
core