Results 51 to 60 of about 45,975 (280)
Chemical Geodynamics Insights From a Machine Learning Approach
The radiogenic isotope heterogeneity of oceanic basalts is often assessed using 2D isotope ratio diagrams. But because the underlying data are at least six dimensional (87Sr/86Sr, 143Nd/144Nd, 176Hf/177Hf, and 208,207,206Pb/204Pb), it is important to ...
A. Stracke +4 more
doaj +1 more source
Does depleted mantle form an intrinsic part of the Iceland plume? [PDF]
Icelandic basalt ranges in composition from voluminous tholeiite, erupted in the rift zones, to small-volume, mildly alkaline basalt erupted off-axis.
Andrew D. Saunders +37 more
core +1 more source
This table of contents illustrates that the mechanism for mitigating Sr segregation depends strongly on the chemistry of the coating layer. HfO2 electrostatically stabilizes the surface by lowering the surface oxygen vacancies, which serve as the driving force for Sr migration. On the other hand, Al2O3 and Fe2O3 react with segregated Sr to form Sr‐Al‐O
Jongsu Seo +8 more
wiley +1 more source
Single Cell RNA Transcriptomics of Mantle Cell Lymphoma Reveals the Presence of Treatment-Resistant Subclones at the Time of Diagnosis. [PDF]
ABSTRACT Mantle cell lymphoma (MCL) is a B‐cell malignancy with a chronically relapsing clinical course and pronounced genetic heterogeneity. To investigate the clonal dynamics underlying early disease relapse, we performed single‐cell RNA sequencing of paired tumor samples collected at diagnosis and at first relapse. Inference of copy number variants (
Manakov D +14 more
europepmc +2 more sources
An analysis of nearfield normal mode amplitude anomalies of the Landers Earthquake [PDF]
The 1992 Landers earthquake (M_w=7.3) occurred in the middle of the TERRAscope network. Long-period Rayleigh waves recorded at the TERRAscope stations (Δ≤3°) after traveling around the Earth show large amplitude anomalies, one order of magnitude larger ...
Anderson, Don L. +2 more
core +1 more source
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey +6 more
wiley +1 more source
In this study, the orange‐muscle giant abalone (Haliotis gigantea) is used as a model to identify a non‐coding SNP that disrupts the interaction between ITGA8 pre‐mRNA and the splicing factor ILF2, leading to altered ITGA8 splicing. These splicing changes promote carotenoid accumulation in abalone muscle through the regulation of tissue remodeling ...
Xiaohui Wei +17 more
wiley +1 more source
The pyrolite model, which can reproduce the upper-mantle seismic velocity and density profiles, was suggested to have significantly lower velocities and density than seismic models in the lower mantle transition zone (MTZ).
Yajie Zhao +5 more
doaj +1 more source
Dissecting Pirtobrutinib Resistance in Mantle Cell Lymphoma Through Single‐Cell Multi‐Omics
ABSTRACT Pirtobrutinib (PBN), a non‐covalent BTK inhibitor, has been approved by the FDA for relapsed/refractory mantle cell lymphoma (MCL); however, resistance to PBN has been observed. To dissect the molecular dynamics driving PBN resistance, we performed integrative single‐cell multi‐omic profiling (scRNA‐seq, scATAC‐seq, and scDNA‐seq) on ...
Fangfang Yan +10 more
wiley +1 more source
Sr-Nd isotope geochemistry of the early Precambrian sub-alkaline mafic igneous rocks from the southern Bastar craton, Central India [PDF]
Sr–Nd isotope data are reported for the early Precambrian sub-alkaline mafic igneous rocks of the southern Bastar craton, central India. These mafic rocks are mostly dykes but there are a few volcanic exposures.
BL Weaver +39 more
core +1 more source

