Results 11 to 20 of about 182,850 (209)

Predicting survival from colorectal cancer histology slides using deep learning: A retrospective multicenter study [PDF]

, 2019
BACKGROUND: For virtually every patient with colorectal cancer (CRC), hematoxylin-eosin (HE)-stained tissue slides are available. These images contain quantitative information, which is not routinely used to objectively extract prognostic biomarkers.
Brenner, H., Chang-Claude, J., Charoentong, P., Ferber, D., Gaiser, T., Halama, N., Herpel, E., Hoffmeister, M., Jansen, L., Jäger, D., Kather, J. N., Krisam, J., Luedde, T., Marx, A., Reyes-Aldasoro, C. C., Valous, N. A., Weis, C. A., Zörnig, I.   +17 more
core   +2 more sources

Use of MMG signals for the control of powered orthotic devices: Development of a rectus femoris measurement protocol [PDF]

, 2009
Copyright © 2009 Rehabilitation Engineering and Assistive Technology Society (RESNA). This is an Author's Accepted Manuscript of an article published in Assistive Technology, 21(1), 1 - 12, 2009, copyright Taylor & Francis, available online at: http ...
Barry D. T., Childress D. S., Elwell C. E., Ferris D. P., Giacomin J., Kampas P. H., Kendall F. P., Mathworks, McConnell K. G., Orizio C., Rao S. S., Raparelli T., Raparelli T., Redford J. B., Reilly P., Ross S. M., Smith D. B., Yoshitake Y.   +17 more
core   +1 more source

The reliability and validity of a designed setup for the assessment of static back extensor force and endurance in older women with and without hyperkyphosis. [PDF]

, 2018
ObjectiveThe purpose of this study was to investigate the intra-rater reliability and validity of a designed load cell setup for the measurement of back extensor muscle force and endurance.ParticipantsThe study sample included 19 older women with ...
Akbarzadeh Baghban, Alireza, Katzman, Wendy, Khalkhali Zavieh, Minoo, King, Nicole, Manshadi, Farideh Dehghan, Rahimi, Abbas, Roghani, Taybeh, Talebian, Saeed   +7 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

An Evaluation of Functional Hand Bracing and EMG Patterns of the Affected Upper Extremity of the Adult Hemiparetic [PDF]

, 1963
This study project was designed to determine the effects of functional hand splinting on the hemiparetic affected upper extremity of adult subjects. Accordingly, a battery of tests, performed with and without bracing, was used to evaluate the function of
Hastings, Alicia Elizabeth
core   +2 more sources

Analysis of Published Criteria for Clinically Inactive Disease in a Large Juvenile Dermatomyositis Cohort Shows That Skin Disease Is Underestimated [PDF]

, 2015
The Pediatric Rheumatology International Trials Organisation (PRINTO) recently published criteria for classification of patients with juvenile dermatomyositis (DM) as having clinically inactive disease.
Almeida, B, Arnold, K, Campanilho-Marques, R, Juvenile Dermatomyositis Research Group, ., Nistala, K, Pilkington, CA, Wedderburn, LR   +6 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

On the reliability and validity of manual muscle testing: a literature review [PDF]

Chiropractic & Osteopathy, 2007
A body of basic science and clinical research has been generated on the manual muscle test (MMT) since its first peer-reviewed publication in 1915. The aim of this report is to provide an historical overview, literature review, description, synthesis and critique of the reliability and validity of MMT in the evaluation of the musculoskeletal and ...
Cuthbert, Scott C, Goodheart, George J
openaire   +2 more sources

Development and Testing of Reduced Versions of the Manual Muscle Test-8 in Juvenile Dermatomyositis [PDF]

The Journal of Rheumatology, 2020
Objective.To develop and test shortened versions of the Manual Muscle Test-8 (MMT-8) in juvenile dermatomyositis (JDM).Methods.Construction of reduced tools was based on a retrospective analysis of individual scores of MMT-8 muscle groups in 3 multinational datasets.
Silvia Rosina, Giulia C. Varnier, Angela Pistorio, Clarissa Pilkington, Susan Maillard, Adele Civino, Elena Tsitsami, Claudia Bracaglia, Marija Jelusic, Adriana Cespedes-Cruz, Graciela Espada, Rolando Cimaz, Gerard Couillault, Rik Joos, Pierre Quartier, Anand P. Rao, Clara Malattia, Nicolino Ruperto, Alessandro Consolaro, Angelo Ravelli   +19 more
openaire   +5 more sources