Results 91 to 100 of about 128,014 (259)

Contour Cutting with Scissors – A Study on Manual Dexterity and Time Management

open access: yesBulletin of the Transilvania University of Braşov: Series VII: Social Sciences, Law
The article presents a study on the relationship between manual dexterity and time management, considering contour cutting with scissors as an indicator of manual dexterity.
Elena-Simona Indreica
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

In-demand skills: a shield against automation—evidence from online job vacancies

open access: yesJournal for Labour Market Research
This paper investigates how in-demand skills, advertised wages, and occupational exposure to automation co-evolve in Slovakia’s online labor market. Drawing on data covering nearly the full universe of online job vacancies posted in Slovakia in 2022, the
Tomáš Oleš
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Effectiveness of a manual dexterity training program to improve executive functioning in preschool children: an individual difference analysis

open access: yesFrontiers in Cognition
IntroductionThe present study employed the Jacobson-Truax reliable change index (RCI) to examine the effectiveness of a 4-week manual dexterity training program embedded in a socially enriched group setting to improve working memory performance ...
Christina Stuhr   +2 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Relationship between Job Fatigue and Fine Motor Skills in Cable Car Company’s Production Staff [PDF]

open access: yesMuhandisī-i bihdāsht-i ḥirfah/ī
Background and Objective: Job fatigue is considered one of the factors affecting the performance and productivity of workers in work environments. Therefore, the objective of the present study was to investigate the relationship between job fatigue and ...
Mohammad Reza Shahahbi Kaseb   +3 more
doaj  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

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