Results 171 to 180 of about 1,654,996 (316)

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Jeffrey Manufacturing Company portable loader

open access: yes, 1916
This photograph depicts a portable loader owned by the Hamilton Moulding Sand Company, Hamilton, Ohio, and made by the Jeffrey Manufacturing Company of Columbus, Ohio.
Fred A. Behmer for the Jeffrey Manufacturing Company (Photographer)
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Manufacturing cost analysis and exploratory economic evaluation of natural killer cell immunotherapy for paediatric solid tumors. [PDF]

open access: yesClin Transl Immunology
Wahid ST   +6 more
europepmc   +1 more source

Jeffrey Manufacturing Company portable pulverizer

open access: yes, 1913
This photograph depicts a type D portable pulverizer, the first of its type, made by the Jeffrey Manufacturing Company of Columbus, Ohio. This kind of pulverizer was used to crush limestone into fine powder which farmers spread on fields to enrich soil ...
Fred A. Behmer for the Jeffrey Manufacturing Company (Photographer)
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

The carbon footprint of Chimeric Antigen Receptor-T cell manufacturing processes. [PDF]

open access: yesInt J Pharm X
van der Bijl WE   +6 more
europepmc   +1 more source

Jeffrey Manufacturing Company portable rubber belt conveyor

open access: yes, 1920
This is a photograph of a portable rubber belt conveyor made by the Jeffrey Manufacturing Company of Columbus, Ohio, owned by the Modern Foundry Company, of Cincinnati, Ohio.
Fred A. Behmer for the Jeffrey Manufacturing Company (Photographer)
core  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

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