Results 91 to 100 of about 1,282,960 (310)
A project based approach to learning for first year engineering students [PDF]
, 2008 Support for transition from Leaving Certificate and entry to college for 1st year engineering students can be difficult to achieve. This new course offers an innovative project based approach to learning for 1st years with an introduction to design to ...
Corcoran, Brian, Whelan, John
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Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
International Journal of Extreme ManufacturingThe ultimate objective of manufacturing is to construct a universal tool system capable of systematically overcoming the spatiotemporal constraints facing humanity. In this context, Extreme Manufacturing (EM) has emerged.
Chaofan He, Huayong Yang, Yong He
doaj +1 more source
Special Issue of the Manufacturing Engineering Society 2021 (SIMES-2021). [PDF]
Materials (Basel), 2022 Rodríguez-Prieto Á, Trujillo FJ.
europepmc +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
International Journal of Industrial Engineering and Production Research, 2015 This research aims at presenting a consolidated model of data envelopment analysis (DEA) technique and value engineering to select the best manufacturing methods for gate valve covers and ranking the methods using TOPSIS.To do so, efficiency evaluation ...
mahdi karbasian +2 more
doaj
Quality management in construction projects [PDF]
, 2011 [Quality Management in Construction Projects by Abdul Razzak Rumane, CRC Press, Boca Raton, FL, 2011, 434 pp, ISBN 9781439838716] Issues of quality management, quality control and performance against specification have long been the focus of various ...
Coffey, Vaughan
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
The Analysis of design and manufacturing tasks using haptic and immersive VR - Some case studies [PDF]
, 2007 The use of virtual reality in interactive design and manufacture has been researched extensively but the practical application of this technology in industry is still very much in its infancy.
Corney, J.R. +4 more
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