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Transporter Engineering for Microbial Manufacturing
Biotechnology Journal, 2020AbstractMicrobes play an important role in biotransformation and biosynthesis of biofuels, natural products, and polymers. Therefore, microbial manufacturing has been widely used in medicine, industry, and agriculture. However, common strategies including enzyme engineering, pathway optimization, and host engineering are generally inadequate to obtain ...
Ying Zhu, Chen Zhou, Ying Wang, Chun Li
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Manufacturing engineering and information
Proceedings of the 4th conference on Design automation - DAC '67, 1967This paper describes an operating computer-aided system (COMET), which processes Automated Wire List data into many forms required in manufacturing, assembly, installation and automated check out of electrical and electronic systems. The presentation presumes an operating Automated Wire List system and specifies some of the value benefits achieved at ...
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Engineering Holonic Manufacturing Systems
Computers in Industry, 2009Holonic Manufacturing Systems (HMS) was first proposed as a new manufacturing paradigm at the beginning of 1990 and has subsequently received a lot of attention in academic and industrial research. The application of holonic concepts to manufacturing was initially motivated by the inadequacy of existing manufacturing systems in the following two ...
Adriana Giret, Vicente J. Botti
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Globalizing manufacturing engineering education
2004 International Symposium on Technology and Society (IEEE Cat. No.04CH37548), 2004The discipline of manufacturing engineering in the U.S. was established in the 1960s, a period when U.S. corporations and products dominated the global economy. Any form of engineering education that ignores the reality of multinational corporations, global supply chains, and international markets looks increasingly outmoded and provincial. The need to
Karl D. Stephan, Vedaraman Sriraman
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A Methodology for Manufacturing Servitization Engineering
2015 International Conference on Service Science (ICSS), 2015This paper presents an engineering methodological approach to support manufacturing servitization in Virtual Manufacturing Environment (VME) and Ecosystem. This methodology was developed under a European Integrated Project MSEE (Manufacturing Service Ecosystem) and experimented in four companies under the frame of MSEE project.
David Chen 0001, Yves Ducq
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Antibody engineering to improve manufacturability
Protein Expression and Purification, 2018Expression variation among antibodies produced by stably transfected Chinese Hamster Ovary (CHO) cells is well established. While developing CHO-K1 cell lines, we encountered a human monoclonal antibody, mAb B-c, with severe manufacturability issues, including very poor expression and high levels of heavy chain (HC) dimer and high molecular weight ...
Sujeewa D, Wijesuriya +8 more
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Engineering of manufacturing systems within engineering networks
2010 IEEE 15th Conference on Emerging Technologies & Factory Automation (ETFA 2010), 2010Within the engineering of manufacturing systems an important change took place. The prior sequential and strongly disconnected engineering activities of the different stakeholders involved in this process became interlinked and strongly coupled leading to engineering networks.
Lorenz Hundt +2 more
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Human Factors Engineering in Manufacturing
Human Factors: The Journal of the Human Factors and Ergonomics Society, 1969This paper briefly reviews the first participation of human factors engineering in the identification and solution of manufacturing problems at Lockheed Missiles and Space Company. Electronics manufacturing management recognized the need for human factors engineering when new programs, more stringent quality requirements, and hiring of unskilled ...
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