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Manufacturing Molecules Through Metabolic Engineering
Science, 2010Metabolic engineering has the potential to produce from simple, readily available, inexpensive starting materials a large number of chemicals that are currently derived from nonrenewable resources or limited natural resources. Microbial production of natural products has been achieved by transferring product-specific enzymes or entire metabolic ...
Jay D Keasling
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Transporter Engineering for Microbial Manufacturing
Biotechnology Journal, 2020AbstractMicrobes play an important role in biotransformation and biosynthesis of biofuels, natural products, and polymers. Therefore, microbial manufacturing has been widely used in medicine, industry, and agriculture. However, common strategies including enzyme engineering, pathway optimization, and host engineering are generally inadequate to obtain ...
Ying Zhu, Chen Zhou, Ying Wang, Chun Li
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Advanced manufacturing engineering
Journal of Materials Processing Technology, 2005Abstract In this paper reported are some of the activities of the Laboratory of Manufacturing Technology of the NTUA in manufacturing engineering, focusing onto some recent trends and developments in advanced manufacturing of advanced materials, mainly emphasizing my long-standing Greek–Ukrainian–Russian–Hungarian scientific cooperation, also with ...
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Antibody engineering to improve manufacturability
Protein Expression and Purification, 2018Expression variation among antibodies produced by stably transfected Chinese Hamster Ovary (CHO) cells is well established. While developing CHO-K1 cell lines, we encountered a human monoclonal antibody, mAb B-c, with severe manufacturability issues, including very poor expression and high levels of heavy chain (HC) dimer and high molecular weight ...
Sujeewa D, Wijesuriya +8 more
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Manufacturing Excellent Engineers
2018Higher Education Institutions (HEIs) have been criticised by employers, government and graduates themselves, for not adequately developing required work skills. An example of practice that does develop student skills is a short industrial placement (SIP) where students are expected to solve a real problem in a company, in two weeks, working with one ...
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Human Factors Engineering in Manufacturing
Human Factors: The Journal of the Human Factors and Ergonomics Society, 1969This paper briefly reviews the first participation of human factors engineering in the identification and solution of manufacturing problems at Lockheed Missiles and Space Company. Electronics manufacturing management recognized the need for human factors engineering when new programs, more stringent quality requirements, and hiring of unskilled ...
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Manufacturing Engineering Methods
1986Manufacturing Engineering is that branch of professional engineering that requires the education and experience necessary to understand and apply engineering procedures to the manufacturing processes and production methods of industrial products. It requires the ability to plan manufacturing; to research and to develop tools, processes, machines, and ...
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Physiological limitations and opportunities in microbial metabolic engineering
Nature Reviews Microbiology, 2021José Montaño López, Jose L Avalos
exaly