Results 111 to 120 of about 816,445 (307)
Study on Dynamic Load Sharing Performance of Planetary Gears with Flexible Pins for Vertical Mills
Jixie chuandong, 2022 Taking the planetary gear with flexible pins for vertical mills as the research object, a finite element model of flexible pins is established. The dynamics model of planetary gear system with flexible pins is established by considering the effects of ...
Lin Xu, Gao Longfei, Feng Xue
doaj
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Transmission accuracy analysis of parallel compound movable teeth mechanism
Jixie chuandongObjectiveIn the field of parallel compound active tooth transmission, there is relatively little research on the impact of manufacturing errors of key components on transmission accuracy and the compensation relationship between errors.
DU Xuesong +4 more
doaj
Jixie chuandong, 2010 Adopted high-order power function and short modification as the profile modification mode of spur gears used in astronomical telescopes,it can meet the necessity of the contact ratio and improve the static transmission error,and avoid stress ...
冯锦平, 马文礼
doaj
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Misspecified heteroskedasticity in the panel probit model: A small sample comparison of GMM and SML estimators [PDF]
This paper compares generalized method of moments (GMM) and simulated maximum likelihood (SML) approaches to the estimation of the panel probit model. Both techniques circumvent multiple integration of joint density functions without the need to restrict
Joachim Inkmann
core
Human error probabilities computation for manufacturing system simulation using CREAM [PDF]
, 2012 International ...
Caux, Christophe +3 more
core +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source