Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
SOME IMPORTANT FACTORS AFFECTING EVOLUTION OF ACTIVITY BASED COSTING (ABC) SYSTEM IN EGYPTIAN MANUFACTURING FIRMS [PDF]
The present investigation aims to determine the factors affecting evolution of Activity Based Costing (ABC) system in Egyptian case. The study used the survey method to describe and analyze these factors in some Egyptian firms.
Karim MAMDOUH ABBAS
doaj
Export Behavior and Firm Productivity in German Manufacturing: A Firm-Level Analysis [PDF]
This paper examines the causal relationship between productivity and exporting in German manufacturing. We find a causal link from high productivity to presence in foreign markets, as postulated by a recent literature on international trade with heterogeneous firms. We apply a matching technique in order to analyze whether the presence in international
Arnold, Jens Matthias, Hussinger, Katrin
openaire +7 more sources
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Smart manufacturing provides a practical pathway for enhancing economic performance while reducing environmental impact. This study empirically examines the unintended co-benefits of China’s Low-Carbon City Pilot (LCCP) Policy in promoting smart ...
Jiaomei Tang, Wen Gao, Yayun Ren
doaj +1 more source
Exposure of manufacturing firms to future sea level rise in Ho Chi Minh City, Vietnam
Ho Chi Minh City (HCMC) is facing notably high levels in current and future flooding. Simultaneously, the ongoing process of rapid industrialization is characterized by the strong emergence of manufacturing firms within the urban area.
Roxana Leitold, Javier Revilla Diez
doaj +1 more source
The Relationship between Sustainability and Resilience in Supply Chains: An Empirical Study on the Egyptian Manufacturing Firms [PDF]
In the face of increasing environmental concerns, market volatility, and global disruptions, the imperative for sustainable and resilient supply chains has never been more pronounced. This study aims to explore the relationship between the implementation
Mohamed Abdrabou +3 more
doaj +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Effect of Break- Even Analysis on Decision Making of Selected Listed Manufacturing Firms in Nigeria
The study investigated effect of break-even analysis on decision making of listed manufacturing firms in Nigeria, between 2012 and 2021. Specifically, the study investigated the effect of selling price, production cost and sale volume on profit after ...
Akinleye G.T., Adebusoye Olaniyi
doaj
A study of technology adoption in manufacturing firms
PurposeThe purpose of this paper is to study the effect of technology adoption on operational competitiveness by taking an example from international manufacturing companies.Design/methodology/approachThis paper develops a conceptual model to generate strategic flexibility and benefit for a manufacturing firm by managing manufacturing strategy and ...
Kristianto, Yohanes +3 more
openaire +2 more sources

