Results 61 to 70 of about 16,401 (266)

Moderating Effect of Firm Size on Financial Uncertainty Indicators and Financial Performance of Manufacturing Firms in Kenya

Journal of Accounting and Finance in Emerging Economies, 2022
Purpose: To what extend does firm size moderates’ relationship between manufacturing firms’ financial performance and financial uncertainty indicators. This was necessitated below expectation performance of manufacturing firms in Kenya.
Jane Pila, Willy Muturi, Tobias Olweny
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

The Relationship between Sustainability and Resilience in Supply Chains: An Empirical Study on the Egyptian Manufacturing Firms [PDF]

المجلة العربية للإدارة
In the face of increasing environmental concerns, market volatility, and global disruptions, the imperative for sustainable and resilient supply chains has never been more pronounced. This study aims to explore the relationship between the implementation
Mohamed Abdrabou, Magdy Khalaf, Ali El Damaty, Mohamed A. Ragheb   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

MODERATING INFLUENCE OF MANAGERIAL OWNERSHIP ON DEBT FINANCING AND FINANCIAL PERFORMANCE OF MANUFACTURING FIRMS QUOTED ON NIGERIAN STOCK EXCHANGE

Gusau Journal of Accounting and Finance, 2022
The study considered the influence of managerial ownership and debt financing on financial performance of manufacturing firms listed on the Nigerian Stock Exchange.
Abdullahi D. Ibrahim, Ahmed Hassan Ahmed, Ramalan Murtala Muhammed, Zainab Abdulsalami, Aliyu Ahmed Tanko, Aliyu Ahmed Tanko   +5 more
doaj  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

The Export-Productivity Link in Brazilian Manufacturing Firms [PDF]

Economics, 2015
Abstract This paper explores the link between exports and total factor productivity (TFP) in Brazilian manufacturing firms over the period 2000–2008. The Brazilian experience is instructive as it is a case of an economy that expanded aggregate exports significantly, but with stagnant aggregate TFP growth.
Máñez, J.A., Cirera, X., Rochina, M.E., Lederman, D., Sanchis, J.A.   +4 more
openaire   +7 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Management of Production System among Manufacturing Firms in Iloilo

JPAIR, 2009
The purposes of the study were to describe the profile of the manufacturing firms, to ascertain the level of efficiency of the production system, and to describe the factors that influence the production efficiency of the manufacturing firms in the City ...
Victor Jaleco
doaj   +1 more source