Results 41 to 50 of about 295,568 (317)
Effective Improved NSGA-II Algorithm for Multi-Objective Integrated Process Planning and Scheduling
Integrated process planning and scheduling (IPPS) is important for modern manufacturing companies to achieve manufacturing efficiency and improve resource utilization.
Xiaoyu Wen +6 more
doaj +1 more source
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core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
The vibration signals of faulty bearings contain rich feature information in both the time and frequency domains. Effectively leveraging this information is crucial, especially when addressing imbalanced bearing fault datasets, as it can significantly ...
Huachao Jiao +3 more
doaj +1 more source
An Industry Gateway for Rapid Reconfiguration of Manufacturing Processes [PDF]
Manufacturing is typically the backbone of every economy and one of the oldest and most prominent economic sectors worldwide. Therefore, any positive or negative impact on this sector has significant consequences on the entire world economy.
Kiss, T., Arjun, R., Terstyanszky, G.
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
One of the objectives of coupling coordination between the logistics industry and manufacturing industry (hereinafter referred to as “two industries coordination”) is to improve the competitiveness of the manufacturing industry. Using the slacks-based method (SBM) and coupling coordination degree model, the coupling coordination ...
openaire +2 more sources
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Experimental Study on the Reduction Effect of Pit Texture on Disassembly Damage for Interference Fit
After remanufacturing disassembly, several kinds of friction damages can be found on the mating surface of interference fit. These damages should be repaired and the cost is closely related to the severity of damages.
Dan Zhou +4 more
doaj +1 more source
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source

