Results 41 to 50 of about 295,568 (317)

Effective Improved NSGA-II Algorithm for Multi-Objective Integrated Process Planning and Scheduling

open access: yesMathematics, 2023
Integrated process planning and scheduling (IPPS) is important for modern manufacturing companies to achieve manufacturing efficiency and improve resource utilization.
Xiaoyu Wen   +6 more
doaj   +1 more source

(***Bestsellers***) Read Book [PDF] Industry 4.0: Managing The Digital Transformation (Springer Series in Advanced Manufacturing) Full PDF

open access: yes, 2020
Read Or Download Industry 4.0: Managing The Digital Transformation (Springer Series in Advanced Manufacturing) Full Books By by Alp Ustundag (Author), Emre Cevikcan (Author) Read Online => Read Industry 4.0: Managing The Digital Transformation (Springer
(***Bestsellers***) Read Book [PDF] Industry 4.0: Managing The Digital Transformation (Springer Series in Advanced Manufacturing) Full PDF
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Comprehensive Exploitation of Time- and Frequency-Domain Information for Bearing Fault Diagnosis on Imbalanced Datasets via Adaptive Wavelet-like Transform General Adversarial Network and Ensemble Learning

open access: yesSensors
The vibration signals of faulty bearings contain rich feature information in both the time and frequency domains. Effectively leveraging this information is crucial, especially when addressing imbalanced bearing fault datasets, as it can significantly ...
Huachao Jiao   +3 more
doaj   +1 more source

An Industry Gateway for Rapid Reconfiguration of Manufacturing Processes [PDF]

open access: yes, 2022
Manufacturing is typically the backbone of every economy and one of the oldest and most prominent economic sectors worldwide. Therefore, any positive or negative impact on this sector has significant consequences on the entire world economy.
Kiss, T., Arjun, R., Terstyanszky, G.
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Research on the Influence of the Coupling Coordination of the Logistics Industry and Manufacturing Industry on the Upgrading of the Manufacturing Industry

open access: yesIEEE Access, 2022
One of the objectives of coupling coordination between the logistics industry and manufacturing industry (hereinafter referred to as “two industries coordination”) is to improve the competitiveness of the manufacturing industry. Using the slacks-based method (SBM) and coupling coordination degree model, the coupling coordination ...
openaire   +2 more sources

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Experimental Study on the Reduction Effect of Pit Texture on Disassembly Damage for Interference Fit

open access: yesChinese Journal of Mechanical Engineering, 2023
After remanufacturing disassembly, several kinds of friction damages can be found on the mating surface of interference fit. These damages should be repaired and the cost is closely related to the severity of damages.
Dan Zhou   +4 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

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