Results 21 to 30 of about 257,611 (263)

System of Parametric Modelling and Assessing the Production Staff Utilisation as a Basis for Aggregate Production Planning

Applied Sciences, 2021
The requirement to achieve effective solutions in the shortest possible time in the manufacturing environment is essential, and it can be solved only by effective production planning methods.
Martin Krajčovič, Beáta Furmannová, Patrik Grznár, Radovan Furmann, Dariusz Plinta, Radovan Svitek, Ivan Antoniuk   +6 more
doaj   +1 more source

Graph-Based Modeling in Shop Scheduling Problems: Review and Extensions

Applied Sciences, 2021
Graphs are powerful tools to model manufacturing systems and scheduling problems. The complexity of these systems and their scheduling problems has been substantially increased by the ongoing technological development.
Jacqueline Otala, Alden Minard, Golshan Madraki, Seyedamirabbas Mousavian   +3 more
doaj   +1 more source

Rapid 3D printing of hierarchical nanoporous copper structures with self-disintegration capability

Nature Communications
Micro-architected nanoporous metals are widely used in electrochemical and catalytic systems, but conventional powder metallurgy cannot readily produce structurally complex, microscale variants.
Luyang Liu, Natalya K Crawford, Wenbo Wang, Stanislau Niauzorau, Yuxiang Zhu, Fabiano Carvalho de Castro Sene, Yao Wang, Siying Liu, Aishwarya Thotta Jayachandran, Bruno Azeredo, Xiangfan Chen   +10 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A Comprehensive Study on K-Fold Cross-Validation for Hyperparameter Tuning of Deep Neural Network

Journal of Engineering
Nested cross-validation is widely used for evaluating hyperparameter-tuning strategies, but its effectiveness depends strongly on the choice of fold numbers, particularly the outer and inner.
Siwaporn Kunnapapdeelert, Tossawat Chantanom, Nicharee Manakitrungrueng, Nguyen Trong Tri Duc, Jirachai Buddhakulsomsiri, Pornprom Ateetanan, Pham Duc Tai   +6 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Flexible manufacturing systems for mass customisation manufacturing

International Journal of Mass Customisation, 2006
This paper presents innovative approaches in realising and exercising mass customisation in theoretical and practical applications. Strategies of generalised production line platform and modularisation are explored to support dynamic reconfigurations of mass customisation.
Guixiu Qiao, Roberto F. Lu, Charles R. McLean   +2 more
openaire   +2 more sources

Development of Production Simulator for Buffer Size Decisions in Complex Production Systems Using Genetic Algorithm

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2007
Deciding on buffer size for production lines has gained more and more importance because of growing complexity of the production lines and production costs.
Jaber ABU QUDEIRI, Hidehiko YAMAMOTO, Rizauddin RAMLI, Khalid R. Al-MOMANI   +3 more
doaj   +1 more source

Melt-based, solvent-free additive manufacturing of biodegradable polymeric scaffolds with designer microstructures for tailored mechanical/biological properties and clinical applications

Virtual and Physical Prototyping, 2020
Biodegradable scaffolds are considered as the key component of tissue engineering which serve as temporary structural supports for tissue regeneration. The mechanical/biological properties of artificial synthetic polymeric scaffolds are highly dependent ...
Zijie Meng, Jiankang He, Jiaxin Li, Yanwen Su, Dichen Li   +4 more
doaj   +1 more source