Results 151 to 160 of about 10,238,486 (293)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Risk factors for malaria-related mortality among children under five at Mbale Regional Referral Hospital, Uganda, 2020-2024: A case-control study. [PDF]

PLOS Glob Public Health
Kwizera P, Migisha R, Mutesi C, Rukundo G, Kabwama SN, Kwesiga B, Bulage L, Ario AR.   +7 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Validating the 2-minute walk test MCID for subacute stroke patients: A Pakistani multicenter cohort analysis. [PDF]

PLoS One
Khan M, Muzamil HS, Osailan AM, Alhammad AA, Khan S, Mushtaq M, Moustafa EBS, Alsalem TNS, Muteesasira E.   +8 more
europepmc   +1 more source

Accepted manuscripts

Sestrinski glasnik/Nursing Journal, 2015
openaire   +5 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

David Reeve, "To remain myself; The history of Onghokham"

Wacana: Journal of the Humanities of Indonesia
Dick van der Meij
doaj   +1 more source

Unmet supportive care needs of head and neck cancer survivors: A scoping review. [PDF]

PLoS One
Huang Y, Chen L, Zeng M, Wu J, Lu Y, Zhang H, Li X, Quan H, Zeng G.   +8 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Biomolecules involved in the metabolism of Escherichia coli affected by photodynamics: A calorimetry study. [PDF]

PLoS One
Ortega-Zambrano D, Lona-Yepez C, Sierra-Valdez FJ, Mercado-Uribe H.   +3 more
europepmc   +1 more source