Results 191 to 200 of about 8,837,414 (325)

The "Dagome iudex": the manuscript tradition of a Greek-Latin document. For a textual criticism approach [PDF]

Kyriakos Papoulidis
openalex   +1 more source

Supplemental material for the manuscript "Extreme genome scrambling in cryptic Oikopleura dioica species".

, 2023
Charles Plessy, Michael J. Mansfield
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Early Diagnostic Value of Contrast-Enhanced MRI in Distinguishing Toxoplasmic Encephalitis from CNS Lymphoma: A Case Report of AIDS with Seronegative Toxoplasmosis. [PDF]

J Int Assoc Provid AIDS Care
Katsuda R, Watanabe D, Nakahara Y, Mizumori Y, Kawamura T.   +4 more
europepmc   +1 more source

Supplementary Data 2/2 PhD manuscript BBD

, 2021
Bertille Burgunter‐Delamare
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Letter to the Editor regarding: "Pre- and post-analytical guidelines for the microscopic diagnosis of melanoma: recommendations from the Brazilian Society of Pathology" - Reply. [PDF]

An Bras Dermatol
Xavier-Júnior JCC, de Paula Alves Coelho KM, de Macedo MP, Lellis RF, de Freitas Pinheiro Junior N, Rocha RF, Comitê de Dermatopatologia da Sociedade Brasileira de Patologia.   +6 more
europepmc   +1 more source

Scientific criticism on manuscript text and works of Seyid Azim Shirvani

Gunel Guliyeva
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

A deep state-space analysis framework for cancer patient latent state estimation and classification from EHR time-series data. [PDF]

PLoS One
Okamoto Y, Nakamura A, Kojima R, Uchino E, Mineharu Y, Harada Y, Kamada M, Sakuragi M, Muto M, Yanagita M, Okuno Y.   +10 more
europepmc   +1 more source