Results 261 to 270 of about 8,837,414 (325)

Effect of graphene addition on tensile, flexural, and hardness behavior of GFRP composites. [PDF]

PLoS One
Nagesh SN, Ramachandra CG, Aruna Kumara PC, Kanti PK, Prakash C, Kumar S, Syum GG, Bhat A.   +7 more
europepmc   +1 more source

manuscript 476421- LB27 LB 28 search engine result files (2)

, 2019
Lucía Borniego
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Between research and introduction to clinical routine-Experience with niraparib from the compassionate use program in Germany (NOGGO Register Analysis). [PDF]

Arch Gynecol Obstet
Grabowski JP, Welz J, Heublein S, Krajewska M, Boer JD, Kraus F, Arndt T, Moosmann N, Heinrich B, Engler T, Agabejli S, Ugur MC, Witteler R, Albrecht O, Müller-Huesmann H, Oskay-Özcelik G, Hettwer C, Kaiser S, Braicu E, Sehouli J.   +19 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Financial constraints and corporate bankruptcy risks in China: The buffer role of cash holdings. [PDF]

PLoS One
Luu QT, Nguyen HTT, Tran TND, Ho TT.
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Impact of COVID-19 on new pharmacotherapy for insomnia: A matched cohort study using the national insurance claims database in Japan. [PDF]

PLoS One
Miyamori D, Yoshida S, Omori W, Kashima S, Ito M.   +4 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Anatomically aware simulation of patient-specific glioblastoma xenografts. [PDF]

PLoS Comput Biol
Malik AA, Krona C, Kundu S, Gerlee P, Nelander S.   +4 more
europepmc   +1 more source